2PI0
| Crystal Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-B enhancer | 分子名称: | Interferon regulatory factor 3, PRDIII-I region of human interferon-B promoter strand 1, PRDIII-I region of human interferon-B promoter strand 2 | 著者 | Escalante, C.R, Nistal-Villan, E, Leyi, S, Garcia-Sastre, A, Aggarwal, A.K. | 登録日 | 2007-04-12 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structure of IRF-3 bound to the PRDIII-I regulatory element of the human interferon-beta enhancer. Mol.Cell, 26, 2007
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6V93
| Structure of DNA Polymerase Zeta/DNA/dNTP Ternary Complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA, ... | 著者 | Malik, R, Kopylov, M, Jain, R, Ubarrextena-Belandia, I, Aggarwal, A.K. | 登録日 | 2019-12-13 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
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6V8P
| Structure of DNA Polymerase Zeta (Apo) | 分子名称: | DNA polymerase delta small subunit, DNA polymerase delta subunit 3, DNA polymerase zeta catalytic subunit, ... | 著者 | Malik, R, Gomez-Llorente, Y, Ubarretxena-Belandia, I, Aggarwal, A.K. | 登録日 | 2019-12-11 | 公開日 | 2020-08-19 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat.Struct.Mol.Biol., 27, 2020
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1AU7
| PIT-1 MUTANT/DNA COMPLEX | 分子名称: | CONSENSUS DNA 25-MER, DNA (5'-D(*CP*TP*TP*CP*CP*TP*CP*AP*TP*GP*TP*AP*TP*AP*TP*AP*C P*AP*TP*GP*AP*GP* GP*A)-3'), PROTEIN PIT-1 | 著者 | Jacobson, E.M, Li, P, Leon-Del-Rio, A, Rosenfeld, M.G, Aggarwal, A.K. | 登録日 | 1997-09-12 | 公開日 | 1998-01-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes Dev., 11, 1997
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1B8I
| STRUCTURE OF THE HOMEOTIC UBX/EXD/DNA TERNARY COMPLEX | 分子名称: | DNA (5'-D(*AP*CP*GP*TP*GP*AP*TP*TP*TP*AP*TP*GP*GP*CP*G)-3'), DNA (5'-D(*GP*TP*CP*GP*CP*CP*AP*TP*AP*AP*AP*TP*CP*AP*C)-3'), PROTEIN (HOMEOBOX PROTEIN EXTRADENTICLE), ... | 著者 | Passner, J.M, Ryoo, H.-D, Shen, L, Mann, R.S, Aggarwal, A.K. | 登録日 | 1999-02-01 | 公開日 | 1999-04-12 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature, 397, 1999
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1D2I
| CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE BGLII COMPLEXED WITH DNA 16-MER | 分子名称: | DNA (5'-D(*TP*AP*TP*TP*AP*TP*AP*GP*AP*TP*CP*TP*AP*TP*AP*A)-3'), MAGNESIUM ION, PROTEIN (RESTRICTION ENDONUCLEASE BGLII) | 著者 | Lukacs, C.M, Kucera, R, Schildkraut, I, Aggarwal, A.K. | 登録日 | 1999-09-23 | 公開日 | 2000-02-21 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution. Nat.Struct.Biol., 7, 2000
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1DFM
| Crystal structure of restriction endonuclease BGLII complexed with DNA 16-mer | 分子名称: | CALCIUM ION, DNA (5'-D(*TP*AP*TP*TP*AP*TP*AP*GP*AP*TP*CP*TP*AP*TP*AP*A)-3'), ENDONUCLEASE BGLII | 著者 | Lukacs, C.M, Kucera, R, Schildkraut, I, Aggarwal, A.K. | 登録日 | 1999-12-06 | 公開日 | 2000-02-21 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Understanding the immutability of restriction enzymes: crystal structure of BglII and its DNA substrate at 1.5 A resolution. Nat.Struct.Biol., 7, 2000
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1ES8
| Crystal structure of free BglII | 分子名称: | ACETIC ACID, RESTRICTION ENDONUCLEASE BGLII | 著者 | Lukacs, C.M, Aggarwal, A.K. | 登録日 | 2000-04-07 | 公開日 | 2001-01-17 | 最終更新日 | 2012-05-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of free BglII reveals an unprecedented scissor-like motion for opening an endonuclease. Nat.Struct.Biol., 8, 2001
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2AQ4
| Ternary complex of the catalytic core of REV1 with DNA and dCTP. | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*C)-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2005-08-17 | 公開日 | 2005-10-04 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Rev1 employs a novel mechanism of DNA synthesis using a protein template. Science, 309, 2005
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2DPJ
| structure of hPoli with DNA and dTTP | 分子名称: | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-05-12 | 公開日 | 2006-07-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat.Struct.Mol.Biol., 13, 2006
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2FLP
| Binary complex of the catalytic core of human DNA polymerase iota with DNA (template G) | 分子名称: | DNA polymerase iota, DNA primer strand, DNA template strand | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-01-06 | 公開日 | 2006-12-05 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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2FLL
| Ternary complex of human DNA polymerase iota with DNA and dTTP | 分子名称: | DNA polymerase iota, DNA primer strand, DNA template strand, ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-01-06 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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2DPI
| Ternary complex of hPoli with DNA and dCTP | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(EDA)P*GP*GP*GP*TP*CP*CP*T)-3', ... | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-05-12 | 公開日 | 2006-07-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Hoogsteen base pair formation promotes synthesis opposite the 1,N(6)-ethenodeoxyadenosine lesion by human DNA polymerase iota. Nat.Struct.Mol.Biol., 13, 2006
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2FLN
| binary complex of catalytic core of human DNA polymerase iota with DNA (template A) | 分子名称: | DNA polymerase iota, DNA primer strand, DNA template strand | 著者 | Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2006-01-06 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An incoming nucleotide imposes an anti to syn conformational change on the templating purine in the human DNA polymerase-iota active site. Structure, 14, 2006
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3GQC
| Structure of human Rev1-DNA-dNTP ternary complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | 著者 | Swan, M.K, Aggarwal, A.K. | 登録日 | 2009-03-24 | 公開日 | 2009-05-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structure of the human Rev1-DNA-dNTP ternary complex. J.Mol.Biol., 390, 2009
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3H3D
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3H40
| Binary complex of human DNA polymerase iota with template U/T | 分子名称: | 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T)-3', DNA polymerase iota, ... | 著者 | Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2009-04-17 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Replication across template T/U by human DNA polymerase-iota. Structure, 17, 2009
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3IN5
| Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*C*CP*TP*AP*(8OG)P*GP*AP*GP*TP*CP*CP*TP*TP*CP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*G*GP*GP*GP*AP*AP*GP*GP*AP*CP*TP*(DOC))-3'), ... | 著者 | Silverstein, T.D, Vasquez-Del Carpio, R, Aggarwal, A.K. | 登録日 | 2009-08-11 | 公開日 | 2009-09-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of human DNA polymerase kappa inserting dATP opposite an 8-oxoG DNA lesion PLOS ONE, 4, 2009
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3IAY
| Ternary complex of DNA polymerase delta | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', 5'-D(*TP*AP*AP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*AP*T)-3', ... | 著者 | Swan, M.K, Aggarwal, A.K. | 登録日 | 2009-07-15 | 公開日 | 2009-09-22 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase delta Nat.Struct.Mol.Biol., 16, 2009
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3H4D
| Ternary complex of human DNA polymerase iota with template U/T and incoming dGTP | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC)), 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T), ... | 著者 | Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2009-04-18 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Replication across template T/U by human DNA polymerase-iota. Structure, 17, 2009
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3H4B
| Ternary complex of human DNA polymerase iota with template U/T and incoming dATP | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 5'-D(*AP*GP*GP*AP*CP*CP*(DOC))-3', 5'-D(*TP*(BRU)P*GP*GP*GP*TP*CP*CP*T)-3', ... | 著者 | Jain, R, Nair, D.T, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. | 登録日 | 2009-04-18 | 公開日 | 2009-07-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Replication across template T/U by human DNA polymerase-iota. Structure, 17, 2009
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6D0M
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6D0Z
| Polymerase Eta cytarabine (AraC) extension ternary complex | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*CP*AP*TP*TP*GP*CP*AP*GP*TP*GP*CP*T)-3'), DNA polymerase eta, ... | 著者 | Rechkoblit, O, Aggarwal, A.K. | 登録日 | 2018-04-11 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural basis for polymerase eta-promoted resistance to the anticancer nucleoside analog cytarabine. Sci Rep, 8, 2018
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5ULX
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5ULP
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