3K2I
 
 | | Human Acyl-coenzyme A thioesterase 4 | | 分子名称: | Acyl-coenzyme A thioesterase 4, CHLORIDE ION, NICKEL (II) ION | | 著者 | Siponen, M.I, Moche, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kraulis, P, Kotenyova, T, Kotzsch, A, Markova, N, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Wisniewska, M, Schuler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-09-30 | | 公開日 | 2009-10-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Human Acyl-coenzyme A thioesterase 4
To be Published
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2CFI
 | | The hydrolase domain of human 10-FTHFD in complex with 6- formyltetrahydropterin | | 分子名称: | 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, 6-FORMYLTETRAHYDROPTERIN, SULFATE ION | | 著者 | Kursula, P, Stenmark, P, Arrowsmith, C, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Ogg, D.J, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J. | | 登録日 | 2006-02-21 | | 公開日 | 2006-03-14 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structures of the Hydrolase Domain of Human 10-Formyltetrahydrofolate Dehydrogenase and its Complex with a Substrate Analogue.
Acta Crystallogr.,Sect.D, 62, 2006
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3KVH
 | | Crystal structure of human protein syndesmos (NUDT16-like protein) | | 分子名称: | CHLORIDE ION, GLYCEROL, Protein syndesmos | | 著者 | Tresaugues, L, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Kotzsch, A, Kraulis, P, Moche, M, Nielsen, T.K, Nyman, T, Persson, C, Roos, A.K, Schuler, H, Schutz, P, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-30 | | 公開日 | 2010-01-19 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of human protein syndesmos (NUDT16L1)
To be Published
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2F73
 | | Crystal structure of human fatty acid binding protein 1 (FABP1) | | 分子名称: | Fatty acid-binding protein, liver | | 著者 | Kursula, P, Thorsell, A.G, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, van den Berg, S, Weigelt, J, Hallberg, B.M, Structural Genomics Consortium (SGC) | | 登録日 | 2005-11-30 | | 公開日 | 2005-12-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of human FABP1
To be Published
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1KGP
 | | R2F from Corynebacterium Ammoniagenes in its Mn substituted form | | 分子名称: | MANGANESE (II) ION, Ribonucleotide reductase protein R2F | | 著者 | Hogbom, M, Huque, Y, Sjoberg, B.M, Nordlund, P. | | 登録日 | 2001-11-28 | | 公開日 | 2001-12-21 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes.
Biochemistry, 41, 2002
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1MMO
 | | CRYSTAL STRUCTURE OF A BACTERIAL NON-HAEM IRON HYDROXYLASE THAT CATALYSES THE BIOLOGICAL OXIDATION OF METHANE | | 分子名称: | ACETIC ACID, FE (III) ION, METHANE MONOOXYGENASE HYDROLASE (ALPHA CHAIN), ... | | 著者 | Rosenzweig, A.C, Frederick, C.A, Lippard, S.J, Nordlund, P. | | 登録日 | 1994-02-22 | | 公開日 | 1995-02-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane.
Nature, 366, 1993
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2FVZ
 | | Human Inositol Monophosphosphatase 2 | | 分子名称: | Inositol monophosphatase 2 | | 著者 | Ogg, D, Hallberg, B.M, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Kursula, P, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Van Den Berg, S, Weigelt, J, Thorsell, A.G, Structural Genomics Consortium (SGC) | | 登録日 | 2006-01-31 | | 公開日 | 2006-02-21 | | 最終更新日 | 2018-05-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of Human Inositol Monophosphatase 2
To be published
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2FIM
 | | Structure of the C-terminal domain of Human Tubby-like protein 1 | | 分子名称: | 3-(N,N-DIMETHYLOCTYLAMMONIO)PROPANESULFONATE, SULFATE ION, Tubby related protein 1 | | 著者 | Hallberg, B.M, Ogg, D, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Kursula, P, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Persson, C. | | 登録日 | 2005-12-29 | | 公開日 | 2006-02-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of the C-terminal domain of Human Tubby-like protein 1
To be published
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3LS8
 | | Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol | | 分子名称: | 3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phenol, CHLORIDE ION, GLYCEROL, ... | | 著者 | Tresaugues, L, Welin, M, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Kraulis, P, Moche, M, Nyman, T, Persson, C, Schuler, H, Schutz, P, Siponen, M.I, Thorsell, A.G, Van den Berg, S, Wahlberg, E, Weigelt, J, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2010-02-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal structure of human PIK3C3 in complex with 3-[4-(4-Morpholinyl)thieno[3,2-d]pyrimidin-2-yl]-phenol
To be Published
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1OQU
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2C6Q
 | | Crystal structure of human guanosine monophosphate reductase 2 GMPR2 in complex with IMP and NADPH | | 分子名称: | GMP REDUCTASE 2, INOSINIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Kursula, P, Stenmark, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Graslund, S, Hammarstrom, M, Hallberg, B.M, Kotenyova, T, Nilsson-Ehle, P, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A, Weigelt, J, Nordlund, P. | | 登録日 | 2005-11-11 | | 公開日 | 2005-11-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Cofactor Mobility Determines Reaction Outcome in the Impdh and Gmpr (Beta-Alpha)(8) Barrel Enzymes.
Nat.Chem.Biol., 7, 2011
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2CAR
 | | Crystal Structure Of Human Inosine Triphosphatase | | 分子名称: | INOSINE TRIPHOSPHATE PYROPHOSPHATASE | | 著者 | Stenmark, P, Kursula, P, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Hogbom, M, Holmberg Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Schuler, H, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Nordlund, P. | | 登録日 | 2005-12-22 | | 公開日 | 2006-01-04 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.09 Å) | | 主引用文献 | Crystal Structure of Human Inosine Triphosphatase. Substrate Binding and Implication of the Inosine Triphosphatase Deficiency Mutation P32T.
J.Biol.Chem., 282, 2007
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2CN1
 | | Crystal structure of Human Cytosolic 5'-Nucleotidase III (NT5C3) | | 分子名称: | CYTOSOLIC 5'-NUCLEOTIDASE III | | 著者 | Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P. | | 登録日 | 2006-05-17 | | 公開日 | 2006-06-12 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition.
J.Biol.Chem., 282, 2007
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4JA3
 | | Partially occluded inward open conformation of the xylose transporter XylE from E. coli | | 分子名称: | CADMIUM ION, D-xylose-proton symporter, LUTETIUM (III) ION | | 著者 | Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. | | 登録日 | 2013-02-18 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
Nat.Struct.Mol.Biol., 20, 2013
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2GK9
 | | Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma | | 分子名称: | phosphatidylinositol-4-phosphate 5-kinase, type II, gamma | | 著者 | Uppenberg, J, Hogbom, M, Ogg, D, Arrowsmith, C, Berglund, H, Collins, R, Ehn, M, Flodin, S, Flores, A, Graslund, S, Holmberg-Schiavone, L, Edwards, A, Hammarstrom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Hallberg, B.M, Structural Genomics Consortium (SGC) | | 登録日 | 2006-03-31 | | 公開日 | 2006-05-02 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of Human Phosphatidylinositol-4-phosphate 5-kinase, type II, gamma
To be Published
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4JA4
 | | Inward open conformation of the xylose transporter XylE from E. coli | | 分子名称: | CADMIUM ION, D-xylose-proton symporter | | 著者 | Quistgaard, E.M, Low, C, Moberg, P, Tresaugues, L, Nordlund, P. | | 登録日 | 2013-02-18 | | 公開日 | 2013-05-01 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | | 主引用文献 | Structural basis for substrate transport in the GLUT-homology family of monosaccharide transporters.
Nat.Struct.Mol.Biol., 20, 2013
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4JZL
 | | Crystal structure of BAP31 vDED at alkaline pH | | 分子名称: | B-cell receptor-associated protein 31, GLYCEROL | | 著者 | Quistgaard, E.M, Low, C, Moberg, P, Guettou, F, Maddi, K, Nordlund, P. | | 登録日 | 2013-04-03 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural and Biophysical Characterization of the Cytoplasmic Domains of Human BAP29 and BAP31.
Plos One, 8, 2013
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4JZP
 | | Crystal structure of BAP31 vDED at acidic pH | | 分子名称: | B-cell receptor-associated protein 31, SULFATE ION, TETRAETHYLENE GLYCOL | | 著者 | Quistgaard, E.M, Low, C, Moberg, P, Guettou, F, Maddi, K, Nordlund, P. | | 登録日 | 2013-04-03 | | 公開日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Biophysical Characterization of the Cytoplasmic Domains of Human BAP29 and BAP31.
Plos One, 8, 2013
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3I35
 | | Human SH3 domain of protein LASP1 | | 分子名称: | LIM and SH3 domain protein 1 | | 著者 | Siponen, M.I, Roos, A.K, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Kragh Nielsen, T, Moche, M, Nyman, T, Persson, C, Sagemark, J, Schueler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-06-30 | | 公開日 | 2009-09-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Human SH3 domain of protein LASP1
TO BE PUBLISHED
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3IHJ
 | | Human alanine aminotransferase 2 in complex with PLP | | 分子名称: | Alanine aminotransferase 2, PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE | | 著者 | Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Moche, M, Nielsen, T.K, Nordlund, P, Nyman, T, Persson, C, Roos, A.K, Schutz, P, Svensson, L, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC) | | 登録日 | 2009-07-30 | | 公開日 | 2009-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Human glutamate pyruvate transaminase 2
To be Published
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5X4Y
 | | Mutant human thymidylate synthase M190K crystallized in a sulfate-containing condition | | 分子名称: | SULFATE ION, Thymidylate synthase | | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | | 登録日 | 2017-02-14 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
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5X5Q
 | | Human thymidylate synthase complexed with dUMP and raltitrexed | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, TOMUDEX, Thymidylate synthase | | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | | 登録日 | 2017-02-17 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
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3IHY
 | | Human PIK3C3 crystal structure | | 分子名称: | Phosphatidylinositol 3-kinase catalytic subunit type 3 | | 著者 | Siponen, M.I, Tresaugues, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Kragh Nielsen, T, Moche, M, Nyman, T, Persson, C, Roos, A.K, Sagemark, J, Schueler, H, Schutz, P, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-07-31 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Human PIK3C3 crystal structure
TO BE PUBLISHED
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3IHL
 | | Human CTPS2 crystal structure | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CTP synthase 2, PHOSPHATE ION | | 著者 | Moche, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Karlberg, T, Kotenyova, T, Kotzsch, A, Kragh Nielsen, T, Nyman, T, Persson, C, Roos, A.K, Sagemark, J, Schueler, H, Schutz, P, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Weigelt, J, Welin, M, Wisniewska, M, Nordlund, P, Structural Genomics Consortium (SGC) | | 登録日 | 2009-07-30 | | 公開日 | 2009-10-13 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Human CTPS2 crystal structure
To be Published
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5X5D
 | | Human thymidylate synthase bound with dUMP | | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Thymidylate synthase | | 著者 | Chen, D, Jansson, A, Larsson, A, Nordlund, P. | | 登録日 | 2017-02-15 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states
J. Biol. Chem., 292, 2017
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