2FIM

Structure of the C-terminal domain of Human Tubby-like protein 1

Summary for 2FIM

DescriptorTubby related protein 1, 3-(N,N-DIMETHYLOCTYLAMMONIO)PROPANESULFONATE, SULFATE ION, ... (4 entities in total)
Functional Keywordstubby filled-barrel, beta-barrel, filled-beta-roll, 12-stranded-beta-barrel, helix-filled-barrel, retinitis pigmentosa, blindness, structural genomics, signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm O00294
Total number of polymer chains2
Total molecular weight63365
Authors
Primary citation
Persson, C.,Ogg, D.,Thorsell, A.G.,Arrowsmith, C.,Berglund, H.,Edwards, A.,Ehn, M.,Flodin, S.,Graslund, S.,Hammarstrom, M.,Hogbom, M.,Holmberg-Schiavone, L.,Kotenyova, T.,Kursula, P.,Nilsson-Ehle, P.,Nordlund, P.,Nyman, T.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Van Den Berg, S.,Weigelt, J.,Hallberg, B.M.
Structure of the C-terminal domain of Human Tubby-like protein 1
To be published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.240605.5%22.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2fim
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Molmil generated image of 2fim
rotated about x axis by 90°
Molmil generated image of 2fim
rotated about y axis by 90°