2FIM

Structure of the C-terminal domain of Human Tubby-like protein 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Tubby related protein 1	polymer	276	31446.7	2	UniProt (O00294) Pfam (PF01167)	Homo sapiens (human)	Tubby-like protein 1
2	C (A)	3-(N,N-DIMETHYLOCTYLAMMONIO)PROPANESULFONATE	non-polymer		279.4	1	Chemie (3DP)
3	D, E (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	F, G (A, B)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, B: 237 - 489 (UniProt: O00294)

PDB	External Database	Details
Met 214	-	expression tag
His 215	-	expression tag
His 216	-	expression tag
His 217	-	expression tag
His 218	-	expression tag
His 219	-	expression tag
His 220	-	expression tag
Ser 221	-	expression tag
Ser 222	-	expression tag
Gly 223	-	expression tag
Val 224	-	expression tag
Asp 225	-	expression tag
Leu 226	-	expression tag
Gly 227	-	expression tag
Thr 228	-	expression tag
Glu 229	-	expression tag
Asn 230	-	expression tag
Leu 231	-	expression tag
Tyr 232	-	expression tag
Phe 233	-	expression tag
Gln 234	-	expression tag
Ser 235	-	expression tag
Met 236	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	62893.4
Non-Polymers*	Number of molecules	3
	Total formula weight	471.6
All*	Total formula weight	63365.0

*Water molecules are not included.