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5L9U
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BU of 5l9u by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with a cross linked Ubiquitin variant-substrate-UBE2C (UBCH10) complex representing key features of multiubiquitination
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-09-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
5L9T
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BU of 5l9t by Molmil
Model of human Anaphase-promoting complex/Cyclosome (APC/C-CDH1) with E2 UBE2S poised for polyubiquitination where UBE2S, APC2, and APC11 are modeled into low resolution density
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Brown, N.G, VanderLinden, R, Dube, P, Haselbach, D, Peters, J.M, Stark, H, Schulman, B.A.
登録日2016-06-11
公開日2016-10-26
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell, 165, 2016
3ONG
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BU of 3ong by Molmil
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
分子名称: SUMO-conjugating enzyme UBC9, Ubiquitin-activating enzyme E1-like
著者Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A.
登録日2010-08-28
公開日2011-01-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
Plos One, 5, 2010
3ONH
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BU of 3onh by Molmil
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
分子名称: Ubiquitin-activating enzyme E1-like
著者Wang, J, Taherbhoy, A.M, Hunt, H.W, Seyedin, S.N, Miller, D.W, Huang, D.T, Schulman, B.A.
登録日2010-08-28
公開日2011-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.601 Å)
主引用文献Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways.
Plos One, 5, 2010
4GAX
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BU of 4gax by Molmil
Crystal Structure of an alpha-Bisabolol synthase mutant
分子名称: Amorpha-4,11-diene synthase
著者Li, J, Peng, Z.
登録日2012-07-26
公開日2013-03-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9948 Å)
主引用文献Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency.
Biochem.J., 451, 2013
4LCD
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BU of 4lcd by Molmil
Structure of an Rsp5xUbxSna3 complex: Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3
分子名称: E3 ubiquitin-protein ligase RSP5, Protein SNA3, Ubiquitin
著者Kamadurai, H.B, Miller, D, Schulman, B.A.
登録日2013-06-21
公開日2013-08-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3.
Elife, 2, 2013
6URQ
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BU of 6urq by Molmil
Complex structure of human poly-ADP-ribosyltransferase TNKS1 ARC2-ARC3 and P antigen family member 4 (PAGE4)
分子名称: GLYCEROL, P antigen family member 4, Poly [ADP-ribose] polymerase tankyrase-1, ...
著者Zheng, Y, Koirala, S, Miller, D, Potts, P.R.
登録日2019-10-24
公開日2020-07-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Tissue-Specific Regulation of the Wnt/ beta-Catenin Pathway by PAGE4 Inhibition of Tankyrase.
Cell Rep, 32, 2020
3BNX
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BU of 3bnx by Molmil
Crystal structure of Aristolochene synthase complexed with farnesyl diphosphate
分子名称: Aristolochene synthase, BETA-MERCAPTOETHANOL, FARNESYL DIPHOSPHATE, ...
著者Shishova, E.Y, Christianson, D.W.
登録日2007-12-14
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray Crystallographic Studies of Substrate Binding to Aristolochene Synthase Suggest a Metal Ion Binding Sequence for Catalysis
J.Biol.Chem., 283, 2008
2LK4
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BU of 2lk4 by Molmil
Structural and mechanistic insights into the interaction between PAT Pyk2 and Paxillin LD motif
分子名称: Protein-tyrosine kinase 2-beta
著者Vanarotti, M, Miller, D, Guibao, C, Zheng, J.
登録日2011-10-04
公開日2012-10-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural and Mechanistic Insights into the Interaction between Pyk2 and Paxillin LD Motifs.
J.Mol.Biol., 426, 2014
7LAD
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BU of 7lad by Molmil
Clobetasol propionate bound to CYP3A5
分子名称: Clobetasol propionate, Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE
著者Buchman, C.D, Miller, D, Wang, J, Jayaraman, S, Chen, T.
登録日2021-01-06
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5.
J.Am.Chem.Soc., 143, 2021
3H5N
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BU of 3h5n by Molmil
Crystal structure of E. coli MccB + ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MccB protein, ...
著者Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A.
登録日2009-04-22
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H5R
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BU of 3h5r by Molmil
Crystal structure of E. coli MccB + Succinimide
分子名称: MccB protein, Microcin C7 analog, SULFATE ION, ...
著者Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A.
登録日2009-04-22
公開日2009-06-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H5A
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BU of 3h5a by Molmil
Crystal structure of E. coli MccB
分子名称: MccB protein, ZINC ION
著者Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A.
登録日2009-04-21
公開日2009-06-16
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H9Q
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BU of 3h9q by Molmil
Crystal structure of E. coli MccB + SeMet MccA
分子名称: MccB protein, Microcin C7 ANALOG, SULFATE ION, ...
著者Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A.
登録日2009-04-30
公開日2009-06-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3H9J
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BU of 3h9j by Molmil
Crystal structure of E. coli MccB + AMPCPP + SeMeT MccA
分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MccB protein, Microcin C7 ANALOG, ...
著者Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A.
登録日2009-04-30
公開日2009-06-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
3HSV
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BU of 3hsv by Molmil
Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATHx-MacroH2ASBCpep2
分子名称: Core histone macro-H2A.1, SULFATE ION, Speckle-type POZ protein, ...
著者Zhuang, M, Schulman, B.A, Miller, D.
登録日2009-06-10
公開日2009-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases.
Mol.Cell, 36, 2009
3H9G
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BU of 3h9g by Molmil
Crystal structure of E. coli MccB + MccA-N7isoASN
分子名称: MccB protein, Microcin C7 analog, SULFATE ION, ...
著者Regni, C.A, Roush, R.F, Miller, D, Nourse, A, Walsh, C.T, Schulman, B.A.
登録日2009-04-30
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献How the MccB bacterial ancestor of ubiquitin E1 initiates biosynthesis of the microcin C7 antibiotic.
Embo J., 28, 2009
7K1M
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BU of 7k1m by Molmil
Peptide from stony coral Heliofungia actiniformis: Hact-1
分子名称: GLY-CYS-HIS-TYR-THR-PRO-PHE-GLY-LEU-ILE-CYS-PHE peptide
著者Daly, N.L, Schmidt, C.A.
登録日2020-09-08
公開日2020-11-25
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Identification and Characterization of a Peptide from the Stony Coral Heliofungia actiniformis .
J.Nat.Prod., 83, 2020
2W27
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BU of 2w27 by Molmil
CRYSTAL STRUCTURE OF THE BACILLUS SUBTILIS YKUI PROTEIN, WITH AN EAL DOMAIN, IN COMPLEX WITH SUBSTRATE C-DI-GMP AND CALCIUM
分子名称: CALCIUM ION, GUANOSINE-5'-MONOPHOSPHATE, YKUI PROTEIN
著者Padavattan, S, AndERSON, W.F, Schirmer, T.
登録日2008-10-24
公開日2009-02-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structures of Ykui and its Complex with Second Messenger C-Di-Gmp Suggests Catalytic Mechanism of Phosphodiester Bond Cleavage by Eal Domains.
J.Biol.Chem., 284, 2009
4KBL
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BU of 4kbl by Molmil
Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism
分子名称: E3 ubiquitin-protein ligase ARIH1, ZINC ION
著者Duda, D.M, Olszewski, J.L, Schulman, B.A.
登録日2013-04-23
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure of HHARI, a RING-IBR-RING Ubiquitin Ligase: Autoinhibition of an Ariadne-Family E3 and Insights into Ligation Mechanism.
Structure, 21, 2013
5V85
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BU of 5v85 by Molmil
The crystal structure of the protein of DegV family COG1307 from Ruminococcus gnavus ATCC 29149 (alternative refinement of PDB 3JR7 with Vaccenic acid)
分子名称: EDD domain protein, DegV family, PHOSPHATE ION, ...
著者Cuypers, M.G, Ericson, M, subramanian, C, White, S.W, Rock, C.O.
登録日2017-03-21
公開日2018-11-21
実験手法X-RAY DIFFRACTION (2.003 Å)
主引用文献The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution
J.Biol.Chem., 2018
5UXY
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BU of 5uxy by Molmil
The crystal structure of a DegV family protein from Eubacterium eligens loaded with heptadecanoic acid to 1.80 Angstrom resolution (ALTERNATIVE REFINEMENT OF PDB 3FDJ with HEPTADECANOIC acid)
分子名称: ACETIC ACID, DegV family protein, SODIUM ION, ...
著者Cuypers, M.G, Ericson, M, subramanian, C, White, S.W, Rock, C.O.
登録日2017-02-23
公開日2018-11-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution
J.Biol.Chem., 2018
6VLX
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BU of 6vlx by Molmil
Crystal structure of FabI from Alistipes finegoldii
分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL
著者Radka, C.D, Seetharaman, J, Rock, C.O.
登録日2020-01-27
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI).
J.Biol.Chem., 295, 2020
6VLY
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BU of 6vly by Molmil
Crystal structure of FabI-NADH complex from Alistipes finegoldii
分子名称: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ...
著者Radka, C.D, Seetharaman, J, Rock, C.O.
登録日2020-01-27
公開日2020-04-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI).
J.Biol.Chem., 295, 2020
5W18
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BU of 5w18 by Molmil
Staphylococcus aureus ClpP in complex with (S)-N-((2R,6S,8aS,14aS,20S,23aS)-2,6-dimethyl-5,8,14,19,23-pentaoxooctadecahydro-1H,5H,14H,19H-pyrido[2,1-i]dipyrrolo[2,1-c:2',1'-l][1]oxa[4,7,10,13]tetraazacyclohexadecin-20-yl)-3-phenyl-2-(3-phenylureido)propanamide
分子名称: 9V7-PHE-SER-PRO-YCP-ALA-MP8, ATP-dependent Clp protease proteolytic subunit
著者Lee, R.E, Griffith, E.C.
登録日2017-06-02
公開日2017-08-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Ureadepsipeptides as ClpP Activators.
Acs Infect Dis., 2019

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