7LAD

Clobetasol propionate bound to CYP3A5

Summary for 7LAD

Entry DOI	10.2210/pdb7lad/pdb
Descriptor	Cytochrome P450 3A5, PROTOPORPHYRIN IX CONTAINING FE, Clobetasol propionate, ... (4 entities in total)
Functional Keywords	cytochrome p450, cyp3a5, membrane protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	56153.22
Authors	Buchman, C.D.,Miller, D.,Wang, J.,Jayaraman, S.,Chen, T. (deposition date: 2021-01-06, release date: 2021-10-27, Last modification date: 2023-10-18)
Primary citation	Wang, J.,Buchman, C.D.,Seetharaman, J.,Miller, D.J.,Huber, A.D.,Wu, J.,Chai, S.C.,Garcia-Maldonado, E.,Wright, W.C.,Chenge, J.,Chen, T. Unraveling the Structural Basis of Selective Inhibition of Human Cytochrome P450 3A5. J.Am.Chem.Soc., 143:18467-18480, 2021 Cited by PubMed: 34648292 DOI: 10.1021/jacs.1c07066 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation