4EP9
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![BU of 4ep9 by Molmil](/molmil-images/mine/4ep9) | CRYSTAL STRUCTURE OF RAT CARNITINE PALMITOYLTRANSFERASE 2 IN COMPLEX WITH CoA-site inhibitor | 分子名称: | 4-[({1-[(5-chloro-2-methoxyphenyl)sulfonyl]-4-methyl-2,3-dihydro-1H-indol-6-yl}carbonyl)amino]benzoic acid, Carnitine O-palmitoyltransferase 2, mitochondrial, ... | 著者 | Rufer, A.C, Thoma, R, Benz, J, Stihle, M, Gsell, B, De Roo, E, Banner, D.W, Mueller, F, Chomienne, O, Hennig, M. | 登録日 | 2012-04-17 | 公開日 | 2013-04-17 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Isothermal titration calorimetry with micelles: Thermodynamics of inhibitor binding to carnitine palmitoyltransferase 2 membrane protein. FEBS Open Bio, 3, 2013
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6DM7
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![BU of 6dm7 by Molmil](/molmil-images/mine/6dm7) | |
6DXM
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![BU of 6dxm by Molmil](/molmil-images/mine/6dxm) | |
6DVT
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![BU of 6dvt by Molmil](/molmil-images/mine/6dvt) | |
6ED9
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![BU of 6ed9 by Molmil](/molmil-images/mine/6ed9) | |
4AFZ
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![BU of 4afz by Molmil](/molmil-images/mine/4afz) | Human Chymase - Fynomer Complex | 分子名称: | CHYMASE, D(-)-TARTARIC ACID, FYNOMER | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | 登録日 | 2012-01-23 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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4AFQ
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![BU of 4afq by Molmil](/molmil-images/mine/4afq) | Human Chymase - Fynomer Complex | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, CHYMASE, CITRATE ANION, ... | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | 登録日 | 2012-01-23 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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4AFS
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![BU of 4afs by Molmil](/molmil-images/mine/4afs) | Human Chymase - Fynomer Complex | 分子名称: | CHYMASE, FYNOMER, GLYCEROL, ... | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | 登録日 | 2012-01-23 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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4AG1
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![BU of 4ag1 by Molmil](/molmil-images/mine/4ag1) | Human Chymase - Fynomer Complex | 分子名称: | CHYMASE, FYNOMER, SULFATE ION | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | 登録日 | 2012-01-23 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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4AG2
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![BU of 4ag2 by Molmil](/molmil-images/mine/4ag2) | Human Chymase - Fynomer Complex | 分子名称: | (2S)-2-hydroxybutanedioic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHYMASE, ... | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | 登録日 | 2012-01-23 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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4AFU
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![BU of 4afu by Molmil](/molmil-images/mine/4afu) | Human Chymase - Fynomer Complex | 分子名称: | CHYMASE, FYNOMER | 著者 | Schlatter, D, Brack, S, Banner, D.W, Batey, S, Benz, J, Bertschinger, J, Huber, W, Joseph, C, Rufer, A, Van Der Kloosters, A, Weber, M, Grabulovski, D, Hennig, M. | 登録日 | 2012-01-23 | 公開日 | 2012-07-11 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain. Mabs, 4, 2012
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3HHD
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![BU of 3hhd by Molmil](/molmil-images/mine/3hhd) | Structure of the Human Fatty Acid Synthase KS-MAT Didomain as a Framework for Inhibitor Design. | 分子名称: | CHLORIDE ION, Fatty acid synthase | 著者 | Pappenberger, G.M, Benz, J, Thoma, R, Rudolph, M.G. | 登録日 | 2009-05-15 | 公開日 | 2010-02-09 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Structure of the human fatty acid synthase KS-MAT didomain as a framework for inhibitor design. J.Mol.Biol., 397, 2010
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1OAT
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5NQU
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![BU of 5nqu by Molmil](/molmil-images/mine/5nqu) | Tubulin Darpin cryo structure | 分子名称: | Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Weinert, T, Olieric, N, James, D, Gashi, D, Nogly, P, Jaeger, K, Steinmetz, M.O, Standfuss, J. | 登録日 | 2017-04-21 | 公開日 | 2017-09-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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5NM5
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![BU of 5nm5 by Molmil](/molmil-images/mine/5nm5) | Tubulin Darpin room-temperature structure in complex with Colchicine determined by serial millisecond crystallography | 分子名称: | Designed Ankyrin Repeat Protein (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Weinert, T, Olieric, N, James, D, Gashi, D, Nogly, P, Jaeger, K, Steinmetz, M.O, Standfuss, J. | 登録日 | 2017-04-05 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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4LKO
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![BU of 4lko by Molmil](/molmil-images/mine/4lko) | Crystal structure of human DPP-IV in complex with BMS-744891 | 分子名称: | 3-(aminomethyl)-4-(2,4-dichlorophenyl)-6-(2-methoxyethyl)-2-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one, Dipeptidyl peptidase 4 | 著者 | Klei, H.E. | 登録日 | 2013-07-08 | 公開日 | 2013-09-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Optimization of Activity, Selectivity, and Liability Profiles in 5-Oxopyrrolopyridine DPP4 Inhibitors Leading to Clinical Candidate (Sa)-2-(3-(Aminomethyl)-4-(2,4-dichlorophenyl)-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)-N,N-dimethylacetamide (BMS-767778). J.Med.Chem., 56, 2013
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2OAT
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![BU of 2oat by Molmil](/molmil-images/mine/2oat) | ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE | 分子名称: | 1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE, ORNITHINE AMINOTRANSFERASE | 著者 | Storici, P, Schirmer, T. | 登録日 | 1998-05-07 | 公開日 | 1998-12-09 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine. J.Mol.Biol., 285, 1999
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6GPX
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![BU of 6gpx by Molmil](/molmil-images/mine/6gpx) | CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812 | 分子名称: | C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2, OLEIC ACID, ZINC ION, ... | 著者 | Pautsch, A, Schnapp, G, Cheng, R, Apel, A. | 登録日 | 2018-06-07 | 公開日 | 2019-01-02 | 最終更新日 | 2019-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists. Structure, 27, 2019
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6GPS
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![BU of 6gps by Molmil](/molmil-images/mine/6gps) | CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812 | 分子名称: | C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2, ZINC ION, [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium | 著者 | Pautsch, A, Schnapp, G. | 登録日 | 2018-06-07 | 公開日 | 2019-01-02 | 最終更新日 | 2019-03-13 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists. Structure, 27, 2019
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8CIC
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![BU of 8cic by Molmil](/molmil-images/mine/8cic) | Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with clinical candidate Etrumadenant | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[2-azanyl-6-[1-[[6-(2-oxidanylpropan-2-yl)pyridin-2-yl]methyl]-1,2,3-triazol-4-yl]pyrimidin-4-yl]-2-methyl-benzenecarbonitrile, ... | 著者 | Cheng, R.K.Y, Markovic-Mueller, S, Hennig, M. | 登録日 | 2023-02-09 | 公開日 | 2023-05-31 | 最終更新日 | 2023-06-14 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Crystal structure of adenosine A 2A receptor in complex with clinical candidate Etrumadenant reveals unprecedented antagonist interaction. Commun Chem, 6, 2023
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5NJM
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![BU of 5njm by Molmil](/molmil-images/mine/5njm) | Lysozyme room-temperature structure determined by serial millisecond crystallography | 分子名称: | Lysozyme C | 著者 | Weinert, T, Vera, L, Marsh, M, James, D, Gashi, D, Nogly, P, Jaeger, K, Standfuss, J. | 登録日 | 2017-03-29 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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5NQT
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![BU of 5nqt by Molmil](/molmil-images/mine/5nqt) | Tubulin Darpin room-temperature structure determined by serial millisecond crystallography | 分子名称: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Weinert, T, Olieric, N, James, D, Gashi, D, Nogly, P, Jaeger, K, Steinmetz, M.O, Standfuss, J. | 登録日 | 2017-04-21 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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5O5W
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![BU of 5o5w by Molmil](/molmil-images/mine/5o5w) | Molybdenum storage protein room-temperature structure determined by serial millisecond crystallography | 分子名称: | (mu3-oxo)-tris(mu2-oxo)-nonakisoxo-trimolybdenum (VI), ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Steffen, B, Weinert, T, Ermler, U, Standfuss, J. | 登録日 | 2017-06-02 | 公開日 | 2017-09-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons. Nat Commun, 8, 2017
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4BEL
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![BU of 4bel by Molmil](/molmil-images/mine/4bel) | BACE2 XAPERONE COMPLEX | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-SECRETASE 2, CHLORIDE ION, ... | 著者 | Banner, D.W, Kuglstatter, A, Benz, J, Stihle, M, Ruf, A. | 登録日 | 2013-03-11 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69, 2013
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4BFB
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![BU of 4bfb by Molmil](/molmil-images/mine/4bfb) | BACE2 XAPERONE COMPLEX | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BETA-SECRETASE 2, XA4813 | 著者 | Banner, D.W, Kuglstatter, A, Benz, J, Stihle, M, Ruf, A. | 登録日 | 2013-03-18 | 公開日 | 2013-05-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69, 2013
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