2OAT

ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE

Summary for 2OAT

DescriptorORNITHINE AMINOTRANSFERASE, 1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE (3 entities in total)
Functional Keywordsaminotransferase, 5-fluoromethylornithine, plp-dependent enzyme, pyridoxal phosphate
Biological sourceHomo sapiens (human)
Cellular locationMitochondrion matrix P04181
Total number of polymer chains3
Total molecular weight146903.85
Authors
Storici, P.,Schirmer, T. (deposition date: 1998-05-07, release date: 1998-12-09, Last modification date: 2011-07-13)
Primary citation
Storici, P.,Capitani, G.,Muller, R.,Schirmer, T.,Jansonius, J.N.
Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine.
J.Mol.Biol., 285:297-309, 1999
PubMed: 9878407 (PDB entries with the same primary citation)
DOI: 10.1006/jmbi.1998.2289
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.95 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers90.4%7.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2oat
no rotation
Molmil generated image of 2oat
rotated about x axis by 90°
Molmil generated image of 2oat
rotated about y axis by 90°