5NM5

Tubulin Darpin room-temperature structure in complex with Colchicine determined by serial millisecond crystallography

Summary for 5NM5

• Entry DOI: 10.2210/pdb5nm5/pdb
• Descriptor: Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed Ankyrin Repeat Protein (DARPIN) D1, ... (8 entities in total)
• Functional Keywords: room-temperature, serial crystallography, structural protein
• Biological source: synthetic construct; More
• Cellular location: Cytoplasm, cytoskeleton: P81947 Q6B856
• Total number of polymer chains: 3
• Total formula weight: 119662.89

Authors

Weinert, T.,Olieric, N.,James, D.,Gashi, D.,Nogly, P.,Jaeger, K.,Steinmetz, M.O.,Standfuss, J. (deposition date: 2017-04-05, release date: 2017-09-27, Last modification date: 2024-01-17)

• Primary citation: Weinert, T.,Olieric, N.,Cheng, R.,Brunle, S.,James, D.,Ozerov, D.,Gashi, D.,Vera, L.,Marsh, M.,Jaeger, K.,Dworkowski, F.,Panepucci, E.,Basu, S.,Skopintsev, P.,Dore, A.S.,Geng, T.,Cooke, R.M.,Liang, M.,Prota, A.E.,Panneels, V.,Nogly, P.,Ermler, U.,Schertler, G.,Hennig, M.,Steinmetz, M.O.,Wang, M.,Standfuss, J.; Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.; Nat Commun, 8:542-542, 2017; PubMed: 28912485; DOI: 10.1038/s41467-017-00630-4

Experimental method

X-RAY DIFFRACTION (2.05 Å)