8FHT
| Cryo-EM structure of human NCC | 分子名称: | CHLORIDE ION, SODIUM ION, Solute carrier family 12 member 3 | 著者 | Zhang, J, Fan, M, Feng, L. | 登録日 | 2022-12-15 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature, 614, 2023
|
|
8FHP
| Cryo-EM structure of human NCC (class 3-1) | 分子名称: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | 著者 | Zhang, J, Fan, M, Feng, L. | 登録日 | 2022-12-14 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature, 614, 2023
|
|
8FHR
| Cryo-EM structure of human NCC (class 3-3) | 分子名称: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | 著者 | Zhang, J, Fan, M, Feng, L. | 登録日 | 2022-12-14 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature, 614, 2023
|
|
8FHO
| Cryo-EM structure of human NCC (class 1) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, SODIUM ION, ... | 著者 | Zhang, J, Fan, M, Feng, L. | 登録日 | 2022-12-14 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature, 614, 2023
|
|
8FHQ
| Cryo-EM structure of human NCC (class 3-2) | 分子名称: | Polythiazide, SODIUM ION, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | 著者 | Zhang, J, Fan, M, Feng, L. | 登録日 | 2022-12-14 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature, 614, 2023
|
|
8FHN
| Cryo-EM structure of human NCC (class 2) | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Polythiazide, Solute carrier family 12 member 2,Solute carrier family 12 member 3 chimera | 著者 | Zhang, J, Fan, M, Feng, L. | 登録日 | 2022-12-14 | 公開日 | 2023-02-15 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure and thiazide inhibition mechanism of the human Na-Cl cotransporter. Nature, 614, 2023
|
|
8JJT
| |
7YLQ
| Crystal structure of Microcystinase C from Sphingomonas sp. ACM-3962 at 2.6 A resolution | 分子名称: | CALCIUM ION, Microcystinase C, ZINC ION | 著者 | Guo, X, Li, Z, Ding, W, Yin, P, Feng, L. | 登録日 | 2022-07-26 | 公開日 | 2023-08-09 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Crystal structure of Microcystin C from Sphingomonas sp. ACM-3962 at 2.6 A resolution To Be Published
|
|
7DYN
| Phosphorylation of MHC I peptide | 分子名称: | ARG-ARG-PHE-SEP-ARG-SEP-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | 著者 | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J. | 登録日 | 2021-01-22 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
|
|
7CIR
| Peptide phosphorylation modification of MHC class I molecules | 分子名称: | ARG-ARG-PHE-SEP-ARG-SER-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | 著者 | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J, Gao, G.F. | 登録日 | 2020-07-08 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
|
|
7CIS
| Peptide modification of MHC class I molecules | 分子名称: | ARG-ARG-PHE-SEP-ARG-SEP-PRO-ILE-ARG, Beta-2-microglobulin, MHC class I antigen | 著者 | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J, Gao, G.F. | 登録日 | 2020-07-08 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
|
|
7CIQ
| Phosphorylation modification of MHC I polypeptide | 分子名称: | ARG-ARG-PHE-SER-ARG-SER-PRO-ILE-ARG-ARG, Beta-2-microglobulin, MHC class I antigen | 著者 | Sun, M.W, Feng, L, Qi, J.X, Liu, W.J, Gao, G.F. | 登録日 | 2020-07-08 | 公開日 | 2022-03-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Phosphosite-dependent presentation of dual phosphorylated peptides by MHC class I molecules. Iscience, 25, 2022
|
|
5JL4
| |
3PUP
| Structure of Glycogen Synthase Kinase 3 beta (GSK3B) in complex with a ruthenium octasporine ligand (OS1) | 分子名称: | Glycogen synthase kinase-3 beta, Ruthenium octasporine | 著者 | Filippakopoulos, P, Kraling, K, Essen, L.O, Meggers, E, Knapp, S. | 登録日 | 2010-12-06 | 公開日 | 2010-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors. J.Am.Chem.Soc., 133, 2011
|
|
8IN7
| |
8WRM
| XBB.1.5 spike protein in complex with ACE2 | 分子名称: | Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Feng, L.L, Feng, L.L. | 登録日 | 2023-10-15 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.34 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19, 2023
|
|
8WRH
| SARS-CoV-2 XBB.1.5.70 in complex with ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S2' | 著者 | Feng, L.L, Feng, L.L. | 登録日 | 2023-10-14 | 公開日 | 2023-11-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19, 2023
|
|
8WRO
| XBB.1.5.10 spike protein in complex with ACE2 | 分子名称: | Processed angiotensin-converting enzyme 2, Spike glycoprotein,Spike glycoprotein,Spike glycoprotein,Fusion protein | 著者 | Feng, L.L, Feng, L.L. | 登録日 | 2023-10-15 | 公開日 | 2023-12-06 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19, 2023
|
|
8WTJ
| XBB.1.5.70 spike protein in complex with ACE2 | 分子名称: | Processed angiotensin-converting enzyme 2, Spike glycoprotein | 著者 | Feng, L.L, Feng, L.L. | 登録日 | 2023-10-18 | 公開日 | 2023-12-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.64 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19, 2023
|
|
8WTD
| XBB.1.5.10 RBD in complex with ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, Spike protein S2' | 著者 | Feng, L.L, Feng, L.L. | 登録日 | 2023-10-18 | 公開日 | 2023-12-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455-456 synergistically enhances antibody evasion and ACE2 binding. Plos Pathog., 19, 2023
|
|
4WYU
| |
4WYT
| |
3A9U
| |
3A9V
| |
5H19
| EED in complex with PRC2 allosteric inhibitor EED162 | 分子名称: | 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | 著者 | Zhao, K, Zhao, M, Luo, X, Zhang, H. | 登録日 | 2016-10-08 | 公開日 | 2017-01-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017
|
|