4PI8
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![BU of 4pi8 by Molmil](/molmil-images/mine/4pi8) | Crystal structure of catalytic mutant E138A of S. Aureus Autolysin E in complex with disaccharide NAG-NAM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-N-acetyl-beta-muramic acid, Autolysin E, CHLORIDE ION, ... | 著者 | Mihelic, M, Renko, M, Jakas, A, Turk, D. | 登録日 | 2014-05-08 | 公開日 | 2015-10-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | The mechanism behind the selection of two different cleavage sites in NAG-NAM polymers Iucrj, 4, 2017
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6ELP
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![BU of 6elp by Molmil](/molmil-images/mine/6elp) | |
6ELX
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![BU of 6elx by Molmil](/molmil-images/mine/6elx) | Oryza sativa DWARF14 | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, GLYCEROL, ... | 著者 | Andersson, I, Carlsson, G.H, Hasse, D. | 登録日 | 2017-09-29 | 公開日 | 2018-05-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The elusive ligand complexes of the DWARF14 strigolactone receptor. J. Exp. Bot., 69, 2018
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6EQU
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![BU of 6equ by Molmil](/molmil-images/mine/6equ) | X-Ray crystal structure of the human carbonic anhydrase II adduct with a membrane-impermeant inhibitor | 分子名称: | 4-[2-(2,4,6-triphenylpyridin-1-ium-1-yl)ethyl]benzenesulfonamide, Carbonic anhydrase 2, ZINC ION | 著者 | Alterio, V, De Simone, G, Esposito, D. | 登録日 | 2017-10-15 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of the human carbonic anhydrase II adduct with 1-(4-sulfamoylphenyl-ethyl)-2,4,6-triphenylpyridinium perchlorate, a membrane-impermeant, isoform selective inhibitor. J Enzyme Inhib Med Chem, 33, 2018
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6E59
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![BU of 6e59 by Molmil](/molmil-images/mine/6e59) | Crystal structure of the human NK1 tachykinin receptor | 分子名称: | 1-(4-{[(2R,3S)-2-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)morpholin-4-yl]methyl}-1H-1,2,3-triazol-5-yl)-N,N-dimethylmethanamine, Substance-P receptor, GlgA glycogen synthase, ... | 著者 | Yin, J, Clark, L, Chapman, K, Shao, Z, Borek, D, Xu, Q, Wang, J, Rosenbaum, D.M. | 登録日 | 2018-07-19 | 公開日 | 2018-12-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal structure of the human NK1tachykinin receptor. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4PED
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![BU of 4ped by Molmil](/molmil-images/mine/4ped) | Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthes | 分子名称: | Chaperone activity of bc1 complex-like, mitochondrial, SULFATE ION | 著者 | Bingman, C.A, Smith, R, Joshi, S, Stefely, J.A, Reidenbach, A.G, Ulbrich, A, Oruganty, O, Floyd, B.J, Jochem, A, Saunders, J.M, Johnson, I.E, Wrobel, R.L, Barber, G.E, Lee, D, Li, S, Kannan, N, Coon, J.J, Pagliarini, D.J, Mitochondrial Protein Partnership (MPP) | 登録日 | 2014-04-22 | 公開日 | 2014-11-19 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Mitochondrial ADCK3 Employs an Atypical Protein Kinase-like Fold to Enable Coenzyme Q Biosynthesis. Mol.Cell, 57, 2015
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4PEL
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![BU of 4pel by Molmil](/molmil-images/mine/4pel) | S1C mutant of Penicillin G acylase from Kluyvera citrophila | 分子名称: | CALCIUM ION, Penicillin G acylase subunit alpha, Penicillin G acylase subunit beta | 著者 | Ramasamy, S, Chand, D, Varshney, N.K, Brannigan, J.A, Wilkinson, A.J, Suresh, C.G. | 登録日 | 2014-04-24 | 公開日 | 2015-07-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Penicillin G acylase To Be Published
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4PFZ
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4PTK
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![BU of 4ptk by Molmil](/molmil-images/mine/4ptk) | Crystal structure of Staphylococcal IMPase-I complex with 3Mg2+ and Phosphate | 分子名称: | GLYCEROL, Inositol monophosphatase family protein, MAGNESIUM ION, ... | 著者 | Dutta, A, Bhattacharyya, S, Dutta, D, Das, A.K. | 登録日 | 2014-03-11 | 公開日 | 2014-10-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.503 Å) | 主引用文献 | Structural elucidation of the binding site and mode of inhibition of Li(+) and Mg(2+) in inositol monophosphatase. Febs J., 281, 2014
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4PTX
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![BU of 4ptx by Molmil](/molmil-images/mine/4ptx) | Halothermothrix orenii beta-glucosidase A, glucose complex | 分子名称: | CACODYLATE ION, Glycoside hydrolase family 1, beta-D-glucopyranose | 著者 | Hassan, N, Nguyen, T.H, Kori, L.D, Patel, B.K.C, Haltrich, D, Divne, C, Tan, T.C. | 登録日 | 2014-03-11 | 公開日 | 2014-09-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biochemical and structural characterization of a thermostable beta-glucosidase from Halothermothrix orenii for galacto-oligosaccharide synthesis. Appl.Microbiol.Biotechnol., 99, 2015
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6E9Z
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![BU of 6e9z by Molmil](/molmil-images/mine/6e9z) | DHF119 filament | 分子名称: | DHF119 filament | 著者 | Lynch, E.M, Shen, H, Fallas, J.A, Kollman, J.M, Baker, D. | 登録日 | 2018-08-01 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | De novo design of self-assembling helical protein filaments. Science, 362, 2018
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6EBA
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![BU of 6eba by Molmil](/molmil-images/mine/6eba) | Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Unoccupied Conformation | 分子名称: | Major facilitator family transporter | 著者 | Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y. | 登録日 | 2018-08-06 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.812 Å) | 主引用文献 | Crystal structure of a bacterial homolog to human lysosomal transporter, spinster Sci Bull (Beijing), 64, 2019
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6EBM
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![BU of 6ebm by Molmil](/molmil-images/mine/6ebm) | The voltage-activated Kv1.2-2.1 paddle chimera channel in lipid nanodiscs, transmembrane domain of subunit alpha | 分子名称: | Potassium voltage-gated channel subfamily A member 2,Potassium voltage-gated channel subfamily B member 2 chimera | 著者 | Matthies, D, Bae, C, Fox, T, Bartesaghi, A, Subramaniam, S, Swartz, K.J. | 登録日 | 2018-08-06 | 公開日 | 2018-08-22 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs. Elife, 7, 2018
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6EER
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![BU of 6eer by Molmil](/molmil-images/mine/6eer) | Structure of glycine-bound GoxA from Pseudoalteromonas luteoviolacea | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GoxA, ... | 著者 | Yukl, E.T, Avalos, D. | 登録日 | 2018-08-15 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural and Spectroscopic Characterization of a Product Schiff Base Intermediate in the Reaction of the Quinoprotein Glycine Oxidase, GoxA. Biochemistry, 58, 2019
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4W1W
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![BU of 4w1w by Molmil](/molmil-images/mine/4w1w) | Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with 7-(diethylamino)-3-(thiophene-2-carbonyl)-2H-chromen-2-one | 分子名称: | 1,2-ETHANEDIOL, 7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, ... | 著者 | Finzel, B.C, Ran, D. | 登録日 | 2014-08-13 | 公開日 | 2015-02-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Target-Based Identification of Whole-Cell Active Inhibitors of Biotin Biosynthesis in Mycobacterium tuberculosis. Chem.Biol., 22, 2015
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6EL5
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![BU of 6el5 by Molmil](/molmil-images/mine/6el5) | Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation | 分子名称: | 8-(2-CHLORO-3,4,5-TRIMETHOXY-BENZYL)-2-FLUORO-9-PENT-4-YLNYL-9H-PURIN-6-YLAMINE, Heat shock protein HSP 90-alpha | 著者 | Musil, D, Lehmann, M, Eggenweiler, H.-M. | 登録日 | 2017-09-27 | 公開日 | 2018-05-30 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations. J Chem Theory Comput, 14, 2018
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6ENY
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![BU of 6eny by Molmil](/molmil-images/mine/6eny) | Structure of the human PLC editing module | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, Calreticulin, ... | 著者 | Trowitzsch, S, Januliene, D, Blees, A, Moeller, A, Tampe, R. | 登録日 | 2017-10-07 | 公開日 | 2017-11-29 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (5.8 Å) | 主引用文献 | Structure of the human MHC-I peptide-loading complex. Nature, 551, 2017
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6EOE
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![BU of 6eoe by Molmil](/molmil-images/mine/6eoe) | Crystal structure of AMPylated GRP78 with nucleotide | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ... | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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6EP3
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![BU of 6ep3 by Molmil](/molmil-images/mine/6ep3) | Lar controls the expression of the Listeria monocytogenes agr system and mediates virulence. | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Lmo0651 protein, ... | 著者 | Pinheiro, J, Lisboa, J, Carvalho, F, Carreaux, A, Santos, N, Cabral, J, Sousa, S, Cabanes, D. | 登録日 | 2017-10-10 | 公開日 | 2018-07-25 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | MouR controls the expression of the Listeria monocytogenes Agr system and mediates virulence. Nucleic Acids Res., 46, 2018
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6EOB
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![BU of 6eob by Molmil](/molmil-images/mine/6eob) | Crystal structure of AMPylated GRP78 in apo form (Crystal form 1) | 分子名称: | 78 kDa glucose-regulated protein, PHOSPHATE ION | 著者 | Yan, Y, Preissler, S, Ron, D, Read, R.J. | 登録日 | 2017-10-09 | 公開日 | 2017-11-01 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | AMPylation targets the rate-limiting step of BiP's ATPase cycle for its functional inactivation. Elife, 6, 2017
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6ERI
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![BU of 6eri by Molmil](/molmil-images/mine/6eri) | Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10 alpha, ... | 著者 | Perez Borema, A, Aibara, S, Paul, B, Tobiasson, V, Kimanius, D, Forsberg, B.O, Wallden, K, Lindahl, E, Amunts, A. | 登録日 | 2017-10-18 | 公開日 | 2018-04-18 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the chloroplast ribosome with chl-RRF and hibernation-promoting factor. Nat Plants, 4, 2018
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6ER6
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![BU of 6er6 by Molmil](/molmil-images/mine/6er6) | Crystal structure of a computationally designed colicin endonuclease and immunity pair colEdes7/Imdes7 | 分子名称: | Endonuclease colEdes7, immunity Imdes7 | 著者 | Netzer, R, Listov, D, Dym, O, Albeck, S, Knop, O, Fleishman, S.J. | 登録日 | 2017-10-17 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Ultrahigh specificity in a network of computationally designed protein-interaction pairs. Nat Commun, 9, 2018
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4PR9
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![BU of 4pr9 by Molmil](/molmil-images/mine/4pr9) | Human Vinculin (residues 891-1066) in complex with PIP | 分子名称: | GLYCEROL, Vinculin, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Chinthalapudi, K, Rangarajan, E.S, Patil, D, Izard, T. | 登録日 | 2014-03-05 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Mechanism and function of lipid-directed oligomerization of vinculin To be Published
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4PY0
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![BU of 4py0 by Molmil](/molmil-images/mine/4py0) | Crystal structure of P2Y12 receptor in complex with 2MeSATP | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(methylsulfanyl)adenosine 5'-(tetrahydrogen triphosphate), P2Y purinoceptor 12, ... | 著者 | Zhang, J, Zhang, K, Gao, Z.G, Paoletta, S, Zhang, D, Han, G.W, Li, T, Ma, L, Zhang, W, Muller, C.E, Yang, H, Jiang, H, Cherezov, V, Katritch, V, Jacobson, K.A, Stevens, R.C, Wu, B, Zhao, Q, GPCR Network (GPCR) | 登録日 | 2014-03-25 | 公開日 | 2014-04-30 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Agonist-bound structure of the human P2Y12 receptor Nature, 509, 2014
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4PYJ
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![BU of 4pyj by Molmil](/molmil-images/mine/4pyj) | human apo-COMT, single domain swap | 分子名称: | CHLORIDE ION, Catechol O-methyltransferase, MAGNESIUM ION, ... | 著者 | Ehler, A, Benz, J, Schlatter, D, Rudolph, M.G. | 登録日 | 2014-03-27 | 公開日 | 2014-06-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mapping the conformational space accessible to catechol-O-methyltransferase. Acta Crystallogr.,Sect.D, 70, 2014
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