8G6T
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![BU of 8g6t by Molmil](/molmil-images/mine/8g6t) | Bromodomain of CBP liganded with inhibitor iCBP2 | 分子名称: | (6S)-1-(3,4-dibromophenyl)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}piperidin-2-one, CREB-binding protein, NICKEL (II) ION | 著者 | Schonbrunn, E, Bikowitz, M. | 登録日 | 2023-02-15 | 公開日 | 2024-02-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nat Commun, 15, 2024
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5C4S
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7XIC
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![BU of 7xic by Molmil](/molmil-images/mine/7xic) | S-ECD (Omicron) in complex with STS165 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | 登録日 | 2022-04-12 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. Iscience, 25, 2022
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7XID
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![BU of 7xid by Molmil](/molmil-images/mine/7xid) | S-ECD (Omicron) in complex with PD of ACE2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | 著者 | Li, Y.N, Shen, Y.P, Zhang, Y.Y, Yan, R.H. | 登録日 | 2022-04-12 | 公開日 | 2022-06-15 | 最終更新日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. Iscience, 25, 2022
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7WWF
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![BU of 7wwf by Molmil](/molmil-images/mine/7wwf) | Crystal structure of BioH3 from Mycolicibacterium smegmatis | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Esterase | 著者 | Yang, J, Xu, Y.C, Gan, J.H, Feng, Y.J. | 登録日 | 2022-02-12 | 公開日 | 2022-07-06 | 最終更新日 | 2023-01-18 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Three enigmatic BioH isoenzymes are programmed in the early stage of mycobacterial biotin synthesis, an attractive anti-TB drug target. Plos Pathog., 18, 2022
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8GA2
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![BU of 8ga2 by Molmil](/molmil-images/mine/8ga2) | Bromodomain of CBP liganded with inhibitor iCBP5 | 分子名称: | (6S)-6-{(5M)-5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1s,4R)-4-methoxycyclohexyl]-1H-benzimidazol-2-yl}-1-phenylpiperidin-2-one, 1,2-ETHANEDIOL, CREB-binding protein | 著者 | Schonbrunn, E, Bikowitz, M. | 登録日 | 2023-02-22 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition. Nat Commun, 15, 2024
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7XY9
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![BU of 7xy9 by Molmil](/molmil-images/mine/7xy9) | Cryo-EM structure of secondary alcohol dehydrogenases TbSADH after carrier-free immobilization based on weak intermolecular interactions | 分子名称: | MAGNESIUM ION, NADP-dependent isopropanol dehydrogenase, ZINC ION | 著者 | Chen, Q, Li, X, Yang, F, Qu, G, Sun, Z.T, Wang, Y.J. | 登録日 | 2022-06-01 | 公開日 | 2023-06-07 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Active and stable alcohol dehydrogenase-assembled hydrogels via synergistic bridging of triazoles and metal ions. Nat Commun, 14, 2023
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6XLV
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7WS2
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![BU of 7ws2 by Molmil](/molmil-images/mine/7ws2) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 510A5 heavy chain, 510A5 light chain, Spike protein S1 | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS8
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![BU of 7ws8 by Molmil](/molmil-images/mine/7ws8) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS0
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![BU of 7ws0 by Molmil](/molmil-images/mine/7ws0) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS6
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![BU of 7ws6 by Molmil](/molmil-images/mine/7ws6) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 510A5 heavy chain, 510A5 light chain, Spike protein S1 | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WSA
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![BU of 7wsa by Molmil](/molmil-images/mine/7wsa) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike protein S1 | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS7
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![BU of 7ws7 by Molmil](/molmil-images/mine/7ws7) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, 510A5 light chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS3
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![BU of 7ws3 by Molmil](/molmil-images/mine/7ws3) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS9
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![BU of 7ws9 by Molmil](/molmil-images/mine/7ws9) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS4
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![BU of 7ws4 by Molmil](/molmil-images/mine/7ws4) | Ultrapotent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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7WS5
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![BU of 7ws5 by Molmil](/molmil-images/mine/7ws5) | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 510A5 heavy chain, ... | 著者 | Guo, H, Gao, Y, Ji, X, Yang, H. | 登録日 | 2022-01-28 | 公開日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structures of Omicron spike complexes and implications for neutralizing antibody development. Cell Rep, 39, 2022
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6RZH
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![BU of 6rzh by Molmil](/molmil-images/mine/6rzh) | Galectin-3C in complex with para-fluoroaryltriazole galactopyranosyl 1-thio-D-glucopyranoside derivative | 分子名称: | (2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(4-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, CHLORIDE ION, Galectin-3 | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | 登録日 | 2019-06-13 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (0.947 Å) | 主引用文献 | Entropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C. Jacs Au, 1, 2021
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6RZG
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![BU of 6rzg by Molmil](/molmil-images/mine/6rzg) | Galectin-3C in complex with meta-fluoroaryltriazole galactopyranosyl 1-thio-D-glucopyranoside derivative | 分子名称: | (2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(3-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, CHLORIDE ION, Galectin-3 | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | 登録日 | 2019-06-13 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.015 Å) | 主引用文献 | Entropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C. Jacs Au, 1, 2021
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6RZF
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![BU of 6rzf by Molmil](/molmil-images/mine/6rzf) | Galectin-3C in complex with ortho-fluoroaryltriazole galactopyranosyl 1-thio-D-glucopyranoside derivative | 分子名称: | (2~{S},3~{R},4~{S},5~{S},6~{R})-2-[(2~{S},3~{R},4~{S},5~{R},6~{R})-4-[4-(2-fluorophenyl)-1,2,3-triazol-1-yl]-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]sulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol, Galectin-3 | 著者 | Kumar, R, Peterson, K, Nilsson, U.J, Logan, D.T. | 登録日 | 2019-06-13 | 公開日 | 2020-07-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.016 Å) | 主引用文献 | Entropy-Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C. Jacs Au, 1, 2021
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3ZUO
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![BU of 3zuo by Molmil](/molmil-images/mine/3zuo) | OMCI in complex with leukotriene B4 | 分子名称: | COMPLEMENT INHIBITOR, LEUKOTRIENE B4 | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | 登録日 | 2011-07-19 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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3BNA
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![BU of 3bna by Molmil](/molmil-images/mine/3bna) | |
3ZUI
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![BU of 3zui by Molmil](/molmil-images/mine/3zui) | OMCI in complex with palmitoleic acid | 分子名称: | COMPLEMENT INHIBITOR, PALMITOLEIC ACID | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | 登録日 | 2011-07-19 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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6PP9
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![BU of 6pp9 by Molmil](/molmil-images/mine/6pp9) | Crystal structure of BRAF:MEK1 complex | 分子名称: | 5-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, CHLORIDE ION, Dual specificity mitogen-activated protein kinase kinase 1, ... | 著者 | Li, K, Gonzalez Del-Pino, G, Park, E, Eck, M.J. | 登録日 | 2019-07-05 | 公開日 | 2019-10-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Architecture of autoinhibited and active BRAF-MEK1-14-3-3 complexes. Nature, 575, 2019
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