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5Z6Z
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BU of 5z6z by Molmil
Crystal structure of human DUX4 homeodomains bound to DNA
分子名称: DNA (5'-D(*CP*CP*AP*CP*TP*AP*AP*CP*CP*TP*AP*AP*TP*CP*AP*CP*AP*CP*C)-3'), DNA (5'-D(*GP*GP*TP*GP*TP*GP*AP*TP*TP*AP*GP*GP*TP*TP*AP*GP*TP*GP*G)-3'), Double homeobox protein 4
著者Li, Y.Y, Wu, B.X, Gan, J.H.
登録日2018-01-26
公開日2018-10-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.301 Å)
主引用文献Structural basis for multiple gene regulation by human DUX4.
Biochem. Biophys. Res. Commun., 505, 2018
8HM0
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BU of 8hm0 by Molmil
F8-A22-E4 complex of MPXV in trimeric form
分子名称: DNA polymerase, DNA polymerase processivity factor component A20, E4R
著者Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H.
登録日2022-12-02
公開日2023-05-31
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant.
Sci Adv, 9, 2023
8HLZ
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BU of 8hlz by Molmil
F8-A22-E4 complex of MPXV in hexameric form
分子名称: DNA polymerase, DNA polymerase processivity factor component A20, E4R
著者Li, Y.N, Shen, Y.P, Hu, Z.W, Yan, R.H.
登録日2022-12-02
公開日2023-05-31
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant.
Sci Adv, 9, 2023
7E8O
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BU of 7e8o by Molmil
Crystal structure of proteinaceous RNase P(PRORP) from Planctomycetes bacterium GWF2_40_8 complexed with Escherichia coli histidine pre-tRNA
分子名称: CALCIUM ION, RNA-free ribonuclease P, histidine pre-tRNA
著者Li, Y.Y, Gan, J.H.
登録日2021-03-02
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P.
Nat Commun, 13, 2022
7E8K
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BU of 7e8k by Molmil
Crystal structure of Proteinaceous RNase P (PRORP) from Planctomycetes bacterium GWF2_40_8
分子名称: RNA-free ribonuclease P, SULFATE ION
著者Li, Y.Y, Gan, J.H.
登録日2021-03-02
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P.
Nat Commun, 13, 2022
7E8J
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BU of 7e8j by Molmil
Crystal structure of Proteinaceous RNase P (PRORP) from Thermococcus celer
分子名称: RNA-free ribonuclease P
著者Li, Y.Y, Gan, J.H.
登録日2021-03-02
公開日2022-03-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P.
Nat Commun, 13, 2022
1BM6
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BU of 1bm6 by Molmil
SOLUTION STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN STROMELYSIN-1 COMPLEXED TO A POTENT NON-PEPTIDIC INHIBITOR, NMR, 20 STRUCTURES
分子名称: 1-METHYLOXY-4-SULFONE-BENZENE, 3-METHYLPYRIDINE, CALCIUM ION, ...
著者Li, Y, Zhang, X, Melton, R, Ganu, V, Gonnella, N.C.
登録日1998-07-29
公開日1999-07-29
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor.
Biochemistry, 37, 1998
5ICT
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BU of 5ict by Molmil
Crystal structure of the Drosophila GluR1A ligand binding domain Y792T mutant complex with glutamate
分子名称: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 1
著者Dharkar, P, Mayer, M.L.
登録日2016-02-23
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
4HRO
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BU of 4hro by Molmil
Crystal structure of H. volcanii small archaeal modifier protein 1
分子名称: CALCIUM ION, Small archaeal modifier protein 1
著者Hao, B.
登録日2012-10-28
公開日2013-10-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystal structure of H. volcanii small archaeal modifier protein 1
To be Published
4HRS
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BU of 4hrs by Molmil
Crystal structure of H. volcanii small archaeal modifier protein 2
分子名称: Small archaeal modifier protein 2
著者Hao, B.
登録日2012-10-28
公開日2013-08-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.
Protein Sci., 22, 2013
7EXC
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BU of 7exc by Molmil
Crystal structure of T2R-TTL-1129A2 complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ...
著者Yang, J.H, Yan, W.
登録日2021-05-26
公開日2022-06-01
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-Based Design and Synthesis of N-Substituted 3-Amino-beta-Carboline Derivatives as Potent alpha beta-Tubulin Degradation Agents
J.Med.Chem., 65, 2022
6UUQ
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BU of 6uuq by Molmil
Structure of Calcineurin bound to RCAN1
分子名称: Calcipressin-1, FE (III) ION, PHOSPHATE ION, ...
著者Sheftic, S, Page, R, Peti, W.
登録日2019-10-31
公開日2020-09-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献The structure of the RCAN1:CN complex explains the inhibition of and substrate recruitment by calcineurin.
Sci Adv, 6, 2020
7C6C
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BU of 7c6c by Molmil
Crystal structure of native chitosanase from Bacillus subtilis MY002
分子名称: (2S)-2-hydroxybutanedioic acid, Chitosanase
著者Gou, Y, Liu, Z.C, Xie, T, Wang, G.G.
登録日2020-05-21
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.258 Å)
主引用文献Structure-based rational design of chitosanase CsnMY002 for high yields of chitobiose.
Colloids Surf B Biointerfaces, 202, 2021
7C6D
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BU of 7c6d by Molmil
Crystal structure of E19A mutant chitosanase from Bacillus subtilis MY002 complexed with 6 GlcN.
分子名称: 2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose-(1-4)-2-amino-2-deoxy-beta-D-glucopyranose, Chitosanase
著者Gou, Y, Liu, Z.C, Xie, T, Wang, G.G.
登録日2020-05-21
公開日2021-03-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.451 Å)
主引用文献Structure-based rational design of chitosanase CsnMY002 for high yields of chitobiose.
Colloids Surf B Biointerfaces, 202, 2021
6K9V
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BU of 6k9v by Molmil
Crystal structure of tubulin in complex with inhibitor D64
分子名称: (5-methoxy-1H-indol-2-yl)-phenyl-methanone, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Yu, Y, Chen, Q.
登録日2019-06-18
公開日2019-08-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.543 Å)
主引用文献Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
Febs Lett., 594, 2020
6KIH
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BU of 6kih by Molmil
Sucrose-phosphate synthase (tll1590) from Thermosynechococcus elongatus
分子名称: 6-O-phosphono-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, Tll1590 protein, URIDINE-5'-DIPHOSPHATE
著者Su, J.
登録日2019-07-18
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Co-crystal Structure ofThermosynechococcus elongatusSucrose Phosphate Synthase With UDP and Sucrose-6-Phosphate Provides Insight Into Its Mechanism of Action Involving an Oxocarbenium Ion and the Glycosidic Bond.
Front Microbiol, 11, 2020
6LDQ
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BU of 6ldq by Molmil
Sucrose-phosphate synthase (tll1590)_27_220_406_426_from Thermosynechococcus elongatus (twinned)
分子名称: THIOCYANATE ION, Tll1590 protein
著者Su, J.
登録日2019-11-22
公開日2020-05-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Co-crystal Structure ofThermosynechococcus elongatusSucrose Phosphate Synthase With UDP and Sucrose-6-Phosphate Provides Insight Into Its Mechanism of Action Involving an Oxocarbenium Ion and the Glycosidic Bond.
Front Microbiol, 11, 2020
8JYV
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BU of 8jyv by Molmil
Crystal structure of the gasdermin from Trichoplax adhaerens
分子名称: Gasdermin pore forming domain-containing protein
著者Zeng, H, Hou, Y.J, Ding, J.
登録日2023-07-04
公開日2024-05-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYW
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BU of 8jyw by Molmil
Cryo-EM structure of the gasdermin pore from Trichoplax adhaerens
分子名称: Gasdermin pore forming domain-containing protein
著者Hou, Y.J, Sun, Q, Zeng, H, Ding, J.
登録日2023-07-04
公開日2024-05-01
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
4F55
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BU of 4f55 by Molmil
Crystal Structure of the Catalytic Domain of the Bacillus cereus SleB Protein
分子名称: PHOSPHATE ION, Spore cortex-lytic enzyme
著者Hao, B.
登録日2012-05-11
公開日2012-07-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Catalytic Domain of the Bacillus cereus SleB Protein, Important in Cortex Peptidoglycan Degradation during Spore Germination.
J.Bacteriol., 194, 2012
3K8S
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BU of 3k8s by Molmil
Crystal Structure of PPARg in complex with T2384
分子名称: 2-chloro-N-{3-chloro-4-[(5-chloro-1,3-benzothiazol-2-yl)sulfanyl]phenyl}-4-(trifluoromethyl)benzenesulfonamide, Peroxisome proliferator-activated receptor gamma
著者Wang, Z.
登録日2009-10-14
公開日2009-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献T2384, a novel antidiabetic agent with unique peroxisome proliferator-activated receptor gamma binding properties
J.Biol.Chem., 283, 2008
5DT6
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BU of 5dt6 by Molmil
Crystal structure of the Drosophila GluR1A ligand binding domain complex with glutamate
分子名称: GLUTAMIC ACID, GLYCEROL, Glutamate receptor 1
著者Dharkar, P, Mayer, M.L.
登録日2015-09-17
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Novel Functional Properties of Drosophila CNS Glutamate Receptors.
Neuron, 92, 2016
6A6B
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BU of 6a6b by Molmil
cryo-em structure of alpha-synuclein fiber
分子名称: Alpha-synuclein
著者Li, Y.W, Zhao, C.Y, Luo, F, Liu, Z, Gui, X, Luo, Z, Zhang, X, Li, D, Liu, C, Li, X.
登録日2018-06-27
公開日2018-07-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Amyloid fibril structure of alpha-synuclein determined by cryo-electron microscopy
Cell Res., 28, 2018
4FAA
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BU of 4faa by Molmil
Structure of Recombinant Cytochrome ba3 Oxidase mutant A120F+A204F from Thermus thermophilus
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ...
著者Li, Y, Chen, Y, Stout, C.D.
登録日2012-05-21
公開日2012-10-31
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献

4FA7
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BU of 4fa7 by Molmil
Structure of Recombinant Cytochrome ba3 Oxidase mutant A204F from Thermus thermophilus
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, COPPER (II) ION, Cytochrome c oxidase polypeptide 2A, ...
著者Li, Y, Chen, Y, Stout, C.D.
登録日2012-05-21
公開日2012-05-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献

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