6VMX
 
 | | Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope | | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Farenc, C, Rossjohn, J, Gras, S. | | 登録日 | 2020-01-28 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals.
J Immunol., 205, 2020
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6VJJ
 | | Crystal Structure of wild-type KRAS4b (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Tran, T.H, Dharmaiah, S, Simanshu, D.K. | | 登録日 | 2020-01-16 | | 公開日 | 2020-11-25 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation.
Nat Commun, 12, 2021
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6WL7
 | | Cryo-EM of Form 2 like peptide filament, 29-20-2 | | 分子名称: | peptide 29-20-2 | | 著者 | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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6WKX
 | | Cryo-EM of Form 1 related peptide filament, 15-10-3 | | 分子名称: | peptide 15-10-3 | | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-17 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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6WL1
 | | Cryo-EM of Form 1 related peptide filament, 36-31-3 | | 分子名称: | peptide 36-31-3 | | 著者 | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-17 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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6WL8
 | | Cryo-EM of Form 2 peptide filament | | 分子名称: | Form 2 peptide | | 著者 | Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. | | 登録日 | 2020-04-18 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials.
Nat Commun, 12, 2021
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8EGZ
 | | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate | | 分子名称: | 1,2-ETHANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, POTASSIUM ION, ... | | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
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8EH0
 | | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with quinoline N-oxide | | 分子名称: | 1,2-ETHANEDIOL, 1-oxo-1lambda~5~-quinoline, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, ... | | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
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8EH1
 | | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline | | 分子名称: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Engineered tyrosine synthase (TmTyrS1), POTASSIUM ION, ... | | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
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8EGY
 | | Engineered holo tyrosine synthase (TmTyrS1) derived from T. maritima TrpB | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | | 登録日 | 2022-09-13 | | 公開日 | 2023-10-04 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase.
Nat.Chem.Biol., 20, 2024
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4QKO
 | | The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms | | 分子名称: | BROMIDE ION, MAGNESIUM ION, Pyocin-S2, ... | | 著者 | Grinter, R, Josts, I, Roszak, A.W, Cogdell, C.J, Walker, D. | | 登録日 | 2014-06-07 | | 公開日 | 2015-06-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Insights into pyocin S2
To be Published
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6EX5
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6EX3
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6EYE
 | | Crystal structure of murine neuroglobin under 150 bar krypton | | 分子名称: | KRYPTON, Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Prange, T, Colloc'h, N, Carpentier, P. | | 登録日 | 2017-11-12 | | 公開日 | 2017-11-29 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Mapping Hydrophobic Tunnels and Cavities in Neuroglobin with Noble Gas under Pressure.
Biophys. J., 113, 2017
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8G1N
 | | Structure of Campylobacter concisus PglC I57M/Q175M Variant with modeled C-terminus | | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MAGNESIUM ION, N,N'-diacetylbacilliosaminyl-1-phosphate transferase, ... | | 著者 | Dodge, G.J, Ray, L.C, Das, D, Imperiali, B, Allen, K.N. | | 登録日 | 2023-02-02 | | 公開日 | 2023-05-31 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Co-conserved sequence motifs are predictive of substrate specificity in a family of monotopic phosphoglycosyl transferases.
Protein Sci., 32, 2023
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6EX4
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4RHP
 | | Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043 | | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, mitochondrial | | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Lee, D, Kogan, S, Maglaqui, M, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) | | 登録日 | 2014-10-02 | | 公開日 | 2014-10-22 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | | 主引用文献 | Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4PP9
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6G4Z
 | | Crystal structure of murine NF-kappaB inducing kinase (NIK) in complex with compound 2f | | 分子名称: | 5-fluoranyl-1-[4-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrol-3-yl]ethynyl]pyridin-2-yl]indazole-3-carboxamide, Mitogen-activated protein kinase kinase kinase 14 | | 著者 | Leonardo-Silvestre, H, McEwan, P.A, Hymowitz, S.G. | | 登録日 | 2018-03-28 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-kappa B Inducing Kinase.
J. Med. Chem., 61, 2018
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6GYI
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6G4Y
 | | Crystal structure of murine NF-kappaB inducing kinase (NIK) in complex with compound 1a | | 分子名称: | 10-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrolidin-3-yl]ethynyl]-~{N}3-(oxan-4-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2,3-dicarboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION | | 著者 | Hole, A.J, Hymowitz, S.G, McEwan, P.A. | | 登録日 | 2018-03-28 | | 公開日 | 2018-07-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-kappa B Inducing Kinase.
J. Med. Chem., 61, 2018
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4PPB
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4PPC
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4PPA
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4P27
 | | Structure of Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Venom allergen-like (VAL) 4 protein | | 著者 | Asojo, O.A. | | 登録日 | 2014-03-02 | | 公開日 | 2014-08-06 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs.
Acta Crystallogr.,Sect.D, 70, 2014
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