6VMX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vmx by Molmil](/molmil-images/mine/6vmx) | Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Farenc, C, Rossjohn, J, Gras, S. | 登録日 | 2020-01-28 | 公開日 | 2020-07-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals. J Immunol., 205, 2020
|
|
6VJJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vjj by Molmil](/molmil-images/mine/6vjj) | Crystal Structure of wild-type KRAS4b (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... | 著者 | Tran, T.H, Dharmaiah, S, Simanshu, D.K. | 登録日 | 2020-01-16 | 公開日 | 2020-11-25 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
|
|
6WL7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wl7 by Molmil](/molmil-images/mine/6wl7) | Cryo-EM of Form 2 like peptide filament, 29-20-2 | 分子名称: | peptide 29-20-2 | 著者 | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-18 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
|
|
6WKX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wkx by Molmil](/molmil-images/mine/6wkx) | Cryo-EM of Form 1 related peptide filament, 15-10-3 | 分子名称: | peptide 15-10-3 | 著者 | Wang, F, Gnewou, O.M, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-17 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
|
|
6WL1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wl1 by Molmil](/molmil-images/mine/6wl1) | Cryo-EM of Form 1 related peptide filament, 36-31-3 | 分子名称: | peptide 36-31-3 | 著者 | Wang, F, Gnewou, O.M, Modlin, C, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-17 | 公開日 | 2020-12-02 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
|
|
6WL8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6wl8 by Molmil](/molmil-images/mine/6wl8) | Cryo-EM of Form 2 peptide filament | 分子名称: | Form 2 peptide | 著者 | Wang, F, Gnewou, O.M, Xu, C, Su, Z, Egelman, E.H, Conticello, V.P. | 登録日 | 2020-04-18 | 公開日 | 2020-12-02 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural analysis of cross alpha-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials. Nat Commun, 12, 2021
|
|
8EGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8egz by Molmil](/molmil-images/mine/8egz) | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate | 分子名称: | 1,2-ETHANEDIOL, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, POTASSIUM ION, ... | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | 登録日 | 2022-09-13 | 公開日 | 2023-10-04 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase. Nat.Chem.Biol., 20, 2024
|
|
8EH0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eh0 by Molmil](/molmil-images/mine/8eh0) | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with quinoline N-oxide | 分子名称: | 1,2-ETHANEDIOL, 1-oxo-1lambda~5~-quinoline, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, ... | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | 登録日 | 2022-09-13 | 公開日 | 2023-10-04 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase. Nat.Chem.Biol., 20, 2024
|
|
8EH1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8eh1 by Molmil](/molmil-images/mine/8eh1) | Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline | 分子名称: | 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, Engineered tyrosine synthase (TmTyrS1), POTASSIUM ION, ... | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | 登録日 | 2022-09-13 | 公開日 | 2023-10-04 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase. Nat.Chem.Biol., 20, 2024
|
|
8EGY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8egy by Molmil](/molmil-images/mine/8egy) | Engineered holo tyrosine synthase (TmTyrS1) derived from T. maritima TrpB | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, POTASSIUM ION, ... | 著者 | Porter, N.J, Almhjell, P.J, Arnold, F.H. | 登録日 | 2022-09-13 | 公開日 | 2023-10-04 | 最終更新日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | The beta-subunit of tryptophan synthase is a latent tyrosine synthase. Nat.Chem.Biol., 20, 2024
|
|
4QKO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4qko by Molmil](/molmil-images/mine/4qko) | The Crystal Structure of the Pyocin S2 Nuclease Domain, Immunity Protein Complex at 1.8 Angstroms | 分子名称: | BROMIDE ION, MAGNESIUM ION, Pyocin-S2, ... | 著者 | Grinter, R, Josts, I, Roszak, A.W, Cogdell, C.J, Walker, D. | 登録日 | 2014-06-07 | 公開日 | 2015-06-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Insights into pyocin S2 To be Published
|
|
6EX5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ex5 by Molmil](/molmil-images/mine/6ex5) | |
6EX3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ex3 by Molmil](/molmil-images/mine/6ex3) | |
6EYE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6eye by Molmil](/molmil-images/mine/6eye) | Crystal structure of murine neuroglobin under 150 bar krypton | 分子名称: | KRYPTON, Neuroglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Prange, T, Colloc'h, N, Carpentier, P. | 登録日 | 2017-11-12 | 公開日 | 2017-11-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Mapping Hydrophobic Tunnels and Cavities in Neuroglobin with Noble Gas under Pressure. Biophys. J., 113, 2017
|
|
8G1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8g1n by Molmil](/molmil-images/mine/8g1n) | Structure of Campylobacter concisus PglC I57M/Q175M Variant with modeled C-terminus | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, MAGNESIUM ION, N,N'-diacetylbacilliosaminyl-1-phosphate transferase, ... | 著者 | Dodge, G.J, Ray, L.C, Das, D, Imperiali, B, Allen, K.N. | 登録日 | 2023-02-02 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Co-conserved sequence motifs are predictive of substrate specificity in a family of monotopic phosphoglycosyl transferases. Protein Sci., 32, 2023
|
|
6EX4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ex4 by Molmil](/molmil-images/mine/6ex4) | |
4RHP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4rhp by Molmil](/molmil-images/mine/4rhp) | Crystal structure of human COQ9 in complex with a phospholipid, Northeast Structural Genomics Consortium Target HR5043 | 分子名称: | DI-PALMITOYL-3-SN-PHOSPHATIDYLETHANOLAMINE, Ubiquinone biosynthesis protein COQ9, mitochondrial | 著者 | Forouhar, F, Lew, S, Seetharaman, J, Wang, H, Lee, D, Kogan, S, Maglaqui, M, Xiao, R, Everett, J.K, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) | 登録日 | 2014-10-02 | 公開日 | 2014-10-22 | 最終更新日 | 2019-08-14 | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | 主引用文献 | Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4PP9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pp9 by Molmil](/molmil-images/mine/4pp9) | |
6G4Z
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g4z by Molmil](/molmil-images/mine/6g4z) | Crystal structure of murine NF-kappaB inducing kinase (NIK) in complex with compound 2f | 分子名称: | 5-fluoranyl-1-[4-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrol-3-yl]ethynyl]pyridin-2-yl]indazole-3-carboxamide, Mitogen-activated protein kinase kinase kinase 14 | 著者 | Leonardo-Silvestre, H, McEwan, P.A, Hymowitz, S.G. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-kappa B Inducing Kinase. J. Med. Chem., 61, 2018
|
|
6GYI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gyi by Molmil](/molmil-images/mine/6gyi) | |
6G4Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g4y by Molmil](/molmil-images/mine/6g4y) | Crystal structure of murine NF-kappaB inducing kinase (NIK) in complex with compound 1a | 分子名称: | 10-[2-[(3~{R})-1-methyl-3-oxidanyl-2-oxidanylidene-pyrrolidin-3-yl]ethynyl]-~{N}3-(oxan-4-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine-2,3-dicarboxamide, Mitogen-activated protein kinase kinase kinase 14, SULFATE ION | 著者 | Hole, A.J, Hymowitz, S.G, McEwan, P.A. | 登録日 | 2018-03-28 | 公開日 | 2018-07-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Scaffold-Hopping Approach To Discover Potent, Selective, and Efficacious Inhibitors of NF-kappa B Inducing Kinase. J. Med. Chem., 61, 2018
|
|
4PPB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ppb by Molmil](/molmil-images/mine/4ppb) | |
4PPC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ppc by Molmil](/molmil-images/mine/4ppc) | |
4PPA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ppa by Molmil](/molmil-images/mine/4ppa) | |
4P27
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p27 by Molmil](/molmil-images/mine/4p27) | Structure of Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Venom allergen-like (VAL) 4 protein | 著者 | Asojo, O.A. | 登録日 | 2014-03-02 | 公開日 | 2014-08-06 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs. Acta Crystallogr.,Sect.D, 70, 2014
|
|