7Z53
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7ZML
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![BU of 7zml by Molmil](/molmil-images/mine/7zml) | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G1-001 | 分子名称: | ATP-dependent DNA helicase Q5, Gluebody G1-001, SULFATE ION, ... | 著者 | Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. | 登録日 | 2022-04-19 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
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7ZMM
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![BU of 7zmm by Molmil](/molmil-images/mine/7zmm) | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2-001 | 分子名称: | ATP-dependent DNA helicase Q5, Gluebody G2-001, ZINC ION | 著者 | Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. | 登録日 | 2022-04-19 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
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7ZMN
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![BU of 7zmn by Molmil](/molmil-images/mine/7zmn) | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G3-048 | 分子名称: | ATP-dependent DNA helicase Q5, Gluebody G3-048, SULFATE ION, ... | 著者 | Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. | 登録日 | 2022-04-19 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
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7ZKR
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![BU of 7zkr by Molmil](/molmil-images/mine/7zkr) | Human GABARAP in complex with stapled peptide Pen3-ortho | 分子名称: | CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, ORTHO-XYLENE, ... | 著者 | Ueffing, A, Brown, H, Willbold, D, Kritzer, J.A, Weiergraeber, O.H. | 登録日 | 2022-04-13 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy. J.Am.Chem.Soc., 144, 2022
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7ZL7
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![BU of 7zl7 by Molmil](/molmil-images/mine/7zl7) | Human GABARAP in complex with stapled peptide Pen8-ortho | 分子名称: | CHLORIDE ION, Gamma-aminobutyric acid receptor-associated protein, ORTHO-XYLENE, ... | 著者 | Ueffing, A, Brown, H, Willbold, D, Kritzer, J.A, Weiergraeber, O.H. | 登録日 | 2022-04-14 | 公開日 | 2022-08-31 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy. J.Am.Chem.Soc., 144, 2022
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8A56
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![BU of 8a56 by Molmil](/molmil-images/mine/8a56) | Coenzyme A-persulfide reductase (CoAPR) from Enterococcus faecalis | 分子名称: | 1,2-ETHANEDIOL, 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE, Coenzyme A-persulfide reductase, ... | 著者 | Costa, S.S, Walsh, B.J, Giedroc, D.P, Brito, J.A. | 登録日 | 2022-06-14 | 公開日 | 2022-09-14 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Metabolic and Structural Insights into Hydrogen Sulfide Mis-Regulation in Enterococcus faecalis. Antioxidants, 11, 2022
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8A7N
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![BU of 8a7n by Molmil](/molmil-images/mine/8a7n) | Crystal Structure of human Brachyury G177D variant in complex with (S)-N-(3-aminopropyl)-3-((1-(2-fluorophenyl)-2-oxopyrrolidin-3-yl)amino)-N-methylbenzamide (CF-2-125) | 分子名称: | N-(3-azanylpropyl)-3-[[(3S)-1-(2-fluorophenyl)-2-oxidanylidene-pyrrolidin-3-yl]amino]-N-methyl-benzamide, PHOSPHATE ION, T-box transcription factor T | 著者 | Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. | 登録日 | 2022-06-21 | 公開日 | 2022-10-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of human Brachyury G177D variant in complex with (S)-N-(3-aminopropyl)-3-((1-(2-fluorophenyl)-2-oxopyrrolidin-3-yl)amino)-N-methylbenzamide (CF-2-125) To Be Published
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8A10
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![BU of 8a10 by Molmil](/molmil-images/mine/8a10) | Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143 | 分子名称: | T-box transcription factor T, UNKNOWN LIGAND | 著者 | Newman, J.A, Gavard, A, Aitkenhead, H, Imprachim, N, Sherestha, L, Burgess-Brown, N.A, von Delft, F, Bountra, C, Gileadi, O. | 登録日 | 2022-05-30 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143 To Be Published
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7ZMS
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![BU of 7zms by Molmil](/molmil-images/mine/7zms) | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G4-043 | 分子名称: | ATP-dependent DNA helicase Q5, Gluebody G4-043, ZINC ION | 著者 | Ye, M, Makola, M, Newman, J.A, Fairhead, M, MacLean, E, Krojer, T, Aitkenhead, H, Bountra, C, Gileadi, O, von Delft, F. | 登録日 | 2022-04-19 | 公開日 | 2022-07-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Gluebodies improve crystal reliability and diversity through transferable nanobody mutations that introduce constitutive crystal contacts To Be Published
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4CYO
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![BU of 4cyo by Molmil](/molmil-images/mine/4cyo) | Leishmania major N-myristoyltransferase in complex with a hybrid inhibitor (compound 21). | 分子名称: | GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, N-{5-[(3S,4R)-1-[(3R)-3-amino-4-(4-chlorophenyl)butanoyl]-4-(hydroxymethyl)pyrrolidin-3-yl]-2-chlorophenyl}-2-(4-fluorophenyl)acetamide, ... | 著者 | Hutton, J.A, Goncalves, V, Brannigan, J.A, Paape, D, Waugh, T, Roberts, S.M, Bell, A.S, Wilkinson, A.J, Smith, D.F, Leatherbarrow, R.J, Tate, E.W. | 登録日 | 2014-04-14 | 公開日 | 2014-10-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structure-Based Design of Potent and Selective Leishmania N- Myristoyltransferase Inhibitors. J.Med.Chem., 57, 2014
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6VRK
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![BU of 6vrk by Molmil](/molmil-images/mine/6vrk) | Cryo-EM structure of the wild-type human serotonin transporter complexed with Br-paroxetine and 8B6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-02-07 | 公開日 | 2020-03-11 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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2SOD
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![BU of 2sod by Molmil](/molmil-images/mine/2sod) | DETERMINATION AND ANALYSIS OF THE 2 ANGSTROM STRUCTURE OF COPPER, ZINC SUPEROXIDE DISMUTASE | 分子名称: | COPPER (II) ION, COPPER,ZINC SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Tainer, J.A, Getzoff, E.D, Richardson, J.S, Richardson, D.C. | 登録日 | 1980-03-25 | 公開日 | 1980-05-07 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Determination and analysis of the 2 A-structure of copper, zinc superoxide dismutase. J.Mol.Biol., 160, 1982
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6W2B
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![BU of 6w2b by Molmil](/molmil-images/mine/6w2b) | Anomalous bromine signal reveals the position of Br-paroxetine complexed with the serotonin transporter at the central site | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-03-05 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (4.7 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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7XT3
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![BU of 7xt3 by Molmil](/molmil-images/mine/7xt3) | Crystal Structure of Hepatitis virus A 2C protein 128-335 aa | 分子名称: | Genome polyprotein, PHOSPHATE ION | 著者 | Chen, P, Wojdyla, J.A, Li, Z, Wang, M, Cui, S. | 登録日 | 2022-05-16 | 公開日 | 2022-07-27 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Biochemical and structural characterization of hepatitis A virus 2C reveals an unusual ribonuclease activity on single-stranded RNA. Nucleic Acids Res., 50, 2022
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6VRH
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![BU of 6vrh by Molmil](/molmil-images/mine/6vrh) | Cryo-EM structure of the wild-type human serotonin transporter complexed with paroxetine and 8B6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-02-07 | 公開日 | 2020-03-11 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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6VRL
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![BU of 6vrl by Molmil](/molmil-images/mine/6vrl) | Cryo-EM structure of the wild-type human serotonin transporter complexed with I-paroxetine and 8B6 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8B6 antibody, heavy chain, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-02-07 | 公開日 | 2020-03-11 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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8A39
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![BU of 8a39 by Molmil](/molmil-images/mine/8a39) | Crystal Structure of PaaX from Escherichia coli W | 分子名称: | DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive, GLYCEROL, ... | 著者 | Molina, R, Alba-Perez, A, Hermoso, J.A. | 登録日 | 2022-06-07 | 公開日 | 2023-07-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural characterization of PaaX, the main repressor of the phenylacetate degradation pathway in Escherichia coli W: A novel fold of transcription regulator proteins. Int.J.Biol.Macromol., 254, 2024
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2VNI
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6W2C
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![BU of 6w2c by Molmil](/molmil-images/mine/6w2c) | Anomalous iodine signal reveals the position of I-paroxetine complexed with the serotonin transporter at the central site | 分子名称: | 8B6 heavy chain antibody fragment, 8B6 light chain antibody fragment, I-paroxetine, ... | 著者 | Coleman, J.A, Navratna, V, Yang, D. | 登録日 | 2020-03-05 | 公開日 | 2020-03-25 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (6.3 Å) | 主引用文献 | Chemical and structural investigation of the paroxetine-human serotonin transporter complex. Elife, 9, 2020
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2VNH
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8ADW
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![BU of 8adw by Molmil](/molmil-images/mine/8adw) | Lipidic alpha-synuclein fibril - polymorph L1C | 分子名称: | Alpha-synuclein | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | 登録日 | 2022-07-11 | 公開日 | 2022-10-12 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADU
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![BU of 8adu by Molmil](/molmil-images/mine/8adu) | Lipidic alpha-synuclein fibril - polymorph L1A | 分子名称: | Alpha-synuclein | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | 登録日 | 2022-07-11 | 公開日 | 2022-10-12 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (3.24 Å) | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8AEX
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![BU of 8aex by Molmil](/molmil-images/mine/8aex) | Lipidic alpha-synuclein fibril - polymorph L3A | 分子名称: | Alpha-synuclein | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | 登録日 | 2022-07-14 | 公開日 | 2022-10-12 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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8ADV
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![BU of 8adv by Molmil](/molmil-images/mine/8adv) | Lipidic alpha-synuclein fibril - polymorph L1B | 分子名称: | Alpha-synuclein | 著者 | Frieg, B, Antonschmidt, L, Dienemann, C, Geraets, J.A, Najbauer, E.E, Matthes, D, de Groot, B.L, Andreas, L.B, Becker, S, Griesinger, C, Schroeder, G.F. | 登録日 | 2022-07-11 | 公開日 | 2022-10-12 | 最終更新日 | 2022-11-23 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | The 3D structure of lipidic fibrils of alpha-synuclein. Nat Commun, 13, 2022
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