8A10

Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143

This is a non-PDB format compatible entry.

Summary for 8A10

• Entry DOI: 10.2210/pdb8a10/pdb
• Descriptor: T-box transcription factor T, 5-[[(3S)-1-(2-chlorophenyl)-2-oxidanylidene-pyrrolidin-3-yl]amino]-2-methyl-benzamide (3 entities in total)
• Functional Keywords: chordoma, brachyury, transcription factor, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 19999.43

Authors

Newman, J.A.,Gavard, A.,Aitkenhead, H.,Imprachim, N.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Bountra, C.,Gileadi, O. (deposition date: 2022-05-30, release date: 2022-07-13, Last modification date: 2025-01-22)

• Primary citation: Newman, J.A.,Gavard, A.,Aitkenhead, H.,Imprachim, N.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Bountra, C.,Gileadi, O.; Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.88 Å)