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8A10

Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143

Summary for 8A10
Entry DOI10.2210/pdb8a10/pdb
DescriptorT-box transcription factor T, UNKNOWN LIGAND (3 entities in total)
Functional Keywordschordoma, brachyury, transcription factor, transcription
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight19655.62
Authors
Newman, J.A.,Gavard, A.,Aitkenhead, H.,Imprachim, N.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Bountra, C.,Gileadi, O. (deposition date: 2022-05-30, release date: 2022-07-13, Last modification date: 2024-06-19)
Primary citationNewman, J.A.,Gavard, A.,Aitkenhead, H.,Imprachim, N.,Sherestha, L.,Burgess-Brown, N.A.,von Delft, F.,Bountra, C.,Gileadi, O.
Crystal Structure of human Brachyury G177D variant in complex with Molpolrt-020-049-143
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.88 Å)
Structure validation

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