7ZKR

Human GABARAP in complex with stapled peptide Pen3-ortho

Summary for 7ZKR

• Entry DOI: 10.2210/pdb7zkr/pdb
• Descriptor: Gamma-aminobutyric acid receptor-associated protein, Pen3-ortho, PHOSPHATE ION, ... (6 entities in total)
• Functional Keywords: autophagy-related protein, stapled peptide, gabarap, inhibitor, protein binding
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 16022.43

Authors

Ueffing, A.,Brown, H.,Willbold, D.,Kritzer, J.A.,Weiergraeber, O.H. (deposition date: 2022-04-13, release date: 2022-08-31, Last modification date: 2024-01-31)

• Primary citation: Brown, H.,Chung, M.,Uffing, A.,Batistatou, N.,Tsang, T.,Doskocil, S.,Mao, W.,Willbold, D.,Bast Jr., R.C.,Lu, Z.,Weiergraber, O.H.,Kritzer, J.A.; Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.; J.Am.Chem.Soc., 144:14687-14697, 2022; PubMed: 35917476; DOI: 10.1021/jacs.2c04699

Experimental method

X-RAY DIFFRACTION (1.1 Å)