7ZKR
Human GABARAP in complex with stapled peptide Pen3-ortho
Summary for 7ZKR
Entry DOI | 10.2210/pdb7zkr/pdb |
Descriptor | Gamma-aminobutyric acid receptor-associated protein, Pen3-ortho, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | autophagy-related protein, stapled peptide, gabarap, inhibitor, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 16022.43 |
Authors | Ueffing, A.,Brown, H.,Willbold, D.,Kritzer, J.A.,Weiergraeber, O.H. (deposition date: 2022-04-13, release date: 2022-08-31, Last modification date: 2024-01-31) |
Primary citation | Brown, H.,Chung, M.,Uffing, A.,Batistatou, N.,Tsang, T.,Doskocil, S.,Mao, W.,Willbold, D.,Bast Jr., R.C.,Lu, Z.,Weiergraber, O.H.,Kritzer, J.A. Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy. J.Am.Chem.Soc., 144:14687-14697, 2022 Cited by PubMed: 35917476DOI: 10.1021/jacs.2c04699 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.1 Å) |
Structure validation
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