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8DSV
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BU of 8dsv by Molmil
The structure of NicA2 in complex with N-methylmyosmine
分子名称: DI(HYDROXYETHYL)ETHER, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FAD-dependent oxidoreductase, ...
著者Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A.
登録日2022-07-22
公開日2023-07-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.
Nat.Chem.Biol., 19, 2023
8DQ8
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BU of 8dq8 by Molmil
The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S in complex with N-methylmyosmine
分子名称: (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE, 1,2-ETHANEDIOL, Amine oxidase, ...
著者Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A.
登録日2022-07-18
公開日2023-07-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.
Nat.Chem.Biol., 19, 2023
8DQ7
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BU of 8dq7 by Molmil
The structure of NicA2 variant F104L/A107T/S146I/G317D/H368R/L449V/N462S from Pseudomonas putida
分子名称: Amine oxidase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
著者Wu, K, Dulchavsky, M, Li, J, Bardwell, J.C.A.
登録日2022-07-18
公開日2023-07-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme.
Nat.Chem.Biol., 2023
8EKY
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BU of 8eky by Molmil
Cryo-EM structure of the human PRDX4-ErP46 complex
分子名称: Peroxiredoxin-4, Thioredoxin domain-containing protein 5
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EKW
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BU of 8ekw by Molmil
Cryo-EM structure of human PRDX4
分子名称: Peroxiredoxin-4
著者Su, C.C.
登録日2022-09-22
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8EM2
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BU of 8em2 by Molmil
Cryo-EM structure of the human GDH/6PGL endoplasmic bifunctional protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GDH/6PGL endoplasmic bifunctional protein
著者Su, C.C.
登録日2022-09-26
公開日2023-05-03
最終更新日2023-11-15
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献High-resolution structural-omics of human liver enzymes.
Cell Rep, 42, 2023
8PPR
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BU of 8ppr by Molmil
Structure of the human outer kinetochore KMN network complex
分子名称: Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ...
著者Yatskevich, S, Barford, D.
登録日2023-07-08
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the human outer kinetochore KMN network complex.
Nat.Struct.Mol.Biol., 2024
8Q85
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BU of 8q85 by Molmil
Outer kinetochore Dam1 protomer monomer Ndc80-Nuf2 coiled-coil complex
分子名称: DASH complex subunit ASK1, DASH complex subunit DAD1, DASH complex subunit DAD2, ...
著者Muir, K.W, Barford, D.
登録日2023-08-17
公開日2023-12-06
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.97 Å)
主引用文献Structural mechanism of outer kinetochore Dam1-Ndc80 complex assembly on microtubules.
Science, 382, 2023
8Q84
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BU of 8q84 by Molmil
Outer kinetochore Dam1 protomer dimer Ndc80-Nuf2 coiled-coil complex
分子名称: DASH complex subunit ASK1, DASH complex subunit DAD1, DASH complex subunit DAD2, ...
著者Muir, K.W, Barford, D.
登録日2023-08-17
公開日2023-12-06
最終更新日2023-12-20
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Structural mechanism of outer kinetochore Dam1-Ndc80 complex assembly on microtubules.
Science, 382, 2023
8FXF
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BU of 8fxf by Molmil
Crystal structure of the coiled-coil domain of TRIM56
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase TRIM56
著者Lou, X.H, Ma, B.B, Zhuang, Y, Li, X.C.
登録日2023-01-24
公開日2023-05-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献TRIM56 coiled-coil domain structure provides insights into its E3 ligase functions.
Comput Struct Biotechnol J, 21, 2023
8P82
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BU of 8p82 by Molmil
Cryo-EM structure of dimeric UBR5
分子名称: E3 ubiquitin-protein ligase UBR5, ZINC ION
著者Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-05-31
公開日2023-06-14
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
8P83
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BU of 8p83 by Molmil
Cryo-EM structure of full-length human UBR5 (homotetramer)
分子名称: E3 ubiquitin-protein ligase UBR5
著者Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-05-31
公開日2023-06-14
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
8QAU
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BU of 8qau by Molmil
Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex
分子名称: DASH complex subunit DAM1, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Muir, K.W, Barford, D.
登録日2023-08-23
公開日2024-04-03
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Mechanism of outer kinetochore assembly on microtubules and its regulation by mitotic error correction
Biorxiv, 2023
4DLP
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BU of 4dlp by Molmil
Crystal structure of methionyl-tRNA synthetase MetRS from Brucella melitensis bound to selenomethionine
分子名称: Aminoacyl-tRNA synthetase, class I:Aminoacyl-tRNA synthetase, class Ia:Methionyl-tRNA synthetase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-02-06
公開日2012-02-15
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis.
Plos One, 11, 2016
2OBR
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BU of 2obr by Molmil
Crystal Structures of P Domain of Norovirus VA387
分子名称: Capsid protein
著者Cao, S, Lou, Z, Jiang, X, Zhang, X.C, Li, X, Rao, Z.
登録日2006-12-20
公開日2007-04-24
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for the recognition of blood group trisaccharides by norovirus.
J.Virol., 81, 2007
6TNT
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BU of 6tnt by Molmil
SUMOylated apoAPC/C with repositioned APC2 WHB domain
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Barford, D, Yatskevich, S.
登録日2019-12-10
公開日2021-01-13
最終更新日2021-07-28
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Molecular mechanisms of APC/C release from spindle assembly checkpoint inhibition by APC/C SUMOylation.
Cell Rep, 34, 2021
5CHL
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BU of 5chl by Molmil
Structural basis of H2A.Z recognition by YL1 histone chaperone component of SRCAP/SWR1 chromatin remodeling complex
分子名称: Histone H2A.Z, Vacuolar protein sorting-associated protein 72 homolog
著者Shan, S, Liang, X, Pan, L, Wu, C, Zhou, Z.
登録日2015-07-10
公開日2016-03-09
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (1.892 Å)
主引用文献Structural basis of H2A.Z recognition by SRCAP chromatin-remodeling subunit YL1
Nat.Struct.Mol.Biol., 23, 2016
5WTW
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BU of 5wtw by Molmil
Hepatitis B virus core protein Y132A mutant in P 41 21 2 Space Group
分子名称: CHLORIDE ION, Core protein
著者Zhou, Z, Xu, Z.H.
登録日2016-12-15
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
4YRI
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BU of 4yri by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 1-(3-bromophenyl)methanamine (Chem 166)
分子名称: 1,2-ETHANEDIOL, 1-(3-bromophenyl)methanamine, DIMETHYL SULFOXIDE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRR
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BU of 4yrr by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with N-(quinolin-3-yl)acetamide (Chem 1691)
分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, HISTIDINE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
5WRE
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BU of 5wre by Molmil
Hepatitis B virus core protein Y132A mutant in complex with heteroaryldihydropyrimidine (HAP_R01)
分子名称: (2S)-1-[[(4R)-4-(2-chloranyl-4-fluoranyl-phenyl)-5-methoxycarbonyl-2-(1,3-thiazol-2-yl)-1,4-dihydropyrimidin-6-yl]methyl]-4,4-bis(fluoranyl)pyrrolidine-2-carboxylic acid, CHLORIDE ION, Core protein, ...
著者Zhou, Z, Xu, Z.H.
登録日2016-12-01
公開日2017-02-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms.
Sci Rep, 7, 2017
4YRP
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BU of 4yrp by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 1-(4-BROMOPHENYL)METHANAMINE (Chem 707)
分子名称: 1,2-ETHANEDIOL, 1-(4-BROMOPHENYL)METHANAMINE, DIMETHYL SULFOXIDE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRJ
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BU of 4yrj by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 4-chlorobenzene-1,2-diamine (Chem 256)
分子名称: 1,2-ETHANEDIOL, 4-chlorobenzene-1,2-diamine, DIMETHYL SULFOXIDE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRS
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BU of 4yrs by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with N-(quinolin-3-yl)propanamide (Chem 1698)
分子名称: HISTIDINE, Histidyl-tRNA synthetase, N-(quinolin-3-yl)propanamide
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4YRF
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BU of 4yrf by Molmil
Crystal structure of T. cruzi Histidyl-tRNA synthetase in complex with 5-bromopyridin-2(1H)-one (Chem 148)
分子名称: 1,2-ETHANEDIOL, 5-bromopyridin-2(1H)-one, DIMETHYL SULFOXIDE, ...
著者Koh, C.-Y, Hol, W.G.J.
登録日2015-03-15
公開日2015-08-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A binding hotspot in Trypanosoma cruzi histidyl-tRNA synthetase revealed by fragment-based crystallographic cocktail screens.
Acta Crystallogr.,Sect.D, 71, 2015

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