7C6Q
 
 | | Novel natural PPARalpha agonist with a unique binding mode | | 分子名称: | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Peroxisome proliferator-activated receptor alpha | | 著者 | Tian, S.Y, Wang, R, Zheng, W.L, Li, Y. | | 登録日 | 2020-05-22 | | 公開日 | 2021-05-26 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Structural Basis for PPARs Activation by The Dual PPAR alpha / gamma Agonist Sanguinarine: A Unique Mode of Ligand Recognition.
Molecules, 26, 2021
|
|
7WIN
 | |
7BED
 | |
7BCY
 | |
1CRZ
 | | CRYSTAL STRUCTURE OF THE E. COLI TOLB PROTEIN | | 分子名称: | TOLB PROTEIN | | 著者 | Abergel, C, Bouveret, E, Claverie, J.-M, Brown, K, Rigal, A, Lazdunski, C, Benedetti, H. | | 登録日 | 1999-08-16 | | 公開日 | 2000-08-16 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structure of the Escherichia coli TolB protein determined by MAD methods at 1.95 A resolution.
Structure Fold.Des., 7, 1999
|
|
3O64
 | | Crystal structure of catalytic domain of TACE with 2-(2-Aminothiazol-4-yl)pyrrolidine-Based Tartrate Diamides | | 分子名称: | (2R,3R)-2,3-dihydroxy-4-{(2R)-2-[2-(methylamino)-5-(methylsulfonyl)-1,3-thiazol-4-yl]pyrrolidin-1-yl}-4-oxo-N-{(1R)-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}butanamide, CALCIUM ION, ISOPROPYL ALCOHOL, ... | | 著者 | Orth, P. | | 登録日 | 2010-07-28 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | 2-(2-Aminothiazol-4-yl)pyrrolidine-based tartrate diamides as potent, selective and orally bioavailable TACE inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
|
|
3LGP
 | |
3PJA
 | |
3QN7
 | | Potent and selective bicyclic peptide inhibitor (UK18) of human urokinase-type plasminogen activator(uPA) | | 分子名称: | 1,3,5-tris(bromomethyl)benzene, Bicyclic peptide inhibitor, Urokinase-type plasminogen activator | | 著者 | Angelini, A, Cendron, L, Touati, J, Winter, G, Zanotti, G, Heinis, C. | | 登録日 | 2011-02-08 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Bicyclic peptide inhibitor reveals large contact interface with a protease target
Acs Chem.Biol., 7, 2012
|
|
5F8U
 | |
7FEO
 | | Crystal structure of AtMBD5 MBD domain | | 分子名称: | Methyl-CpG-binding domain-containing protein 5, SULFATE ION | | 著者 | Zhou, M.Q, Wu, Z.B, Liu, K, Min, J.R, Structural Genomics Consortium (SGC) | | 登録日 | 2021-07-21 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs.
J.Mol.Biol., 434, 2022
|
|
7FEF
 | | Crystal structure of AtMBD6 with DNA | | 分子名称: | DNA (5'-D(*GP*CP*CP*AP*AP*(5CM)P*GP*TP*TP*GP*GP*C)-3'), Methyl-CpG-binding domain-containing protein 6 | | 著者 | Wu, Z.B, Liu, K, Min, J.R. | | 登録日 | 2021-07-19 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Family-wide Characterization of Methylated DNA Binding Ability of Arabidopsis MBDs.
J.Mol.Biol., 434, 2022
|
|
7F2D
 | |
7F2I
 | |
6T6R
 | | Human endoplasmic reticulum aminopeptidase 1 (ERAP1) in complex with (4aR,5S,6R,8S,8aR)-5-(2-(Furan-3-yl)ethyl)-8-hydroxy-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-carboxylic acid | | 分子名称: | (4~{a}~{R},5~{S},6~{R},8~{S},8~{a}~{R})-5-[2-(furan-3-yl)ethyl]-5,6,8~{a}-trimethyl-8-oxidanyl-3,4,4~{a},6,7,8-hexahydronaphthalene-1-carboxylic acid, 1,2-ETHANEDIOL, D-MALATE, ... | | 著者 | Rowland, P. | | 登録日 | 2019-10-18 | | 公開日 | 2020-03-18 | | 最終更新日 | 2020-04-08 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Targeting the Regulatory Site of ER Aminopeptidase 1 Leads to the Discovery of a Natural Product Modulator of Antigen Presentation.
J.Med.Chem., 63, 2020
|
|
2IIZ
 | |
3EQX
 | |
7X2P
 | |
1JV4
 | | Crystal structure of recombinant major mouse urinary protein (rmup) at 1.75 A resolution | | 分子名称: | 2-(SEC-BUTYL)THIAZOLE, CADMIUM ION, Major urinary protein 2 | | 著者 | Kuser, P.R, Franzoni, L, Ferrari, E, Spisni, A, Polikarpov, I. | | 登録日 | 2001-08-28 | | 公開日 | 2001-12-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | The X-ray structure of a recombinant major urinary protein at 1.75 A resolution. A comparative study of X-ray and NMR-derived structures.
Acta Crystallogr.,Sect.D, 57, 2001
|
|
1AN7
 | |
3O98
 | | Glutathionylspermidine synthetase/amidase C59A complex with ADP and Gsp | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Bifunctional glutathionylspermidine synthetase/amidase, GLUTATHIONYLSPERMIDINE, ... | | 著者 | Pai, C.H, Lin, C.H, Wang, A.H.-J. | | 登録日 | 2010-08-04 | | 公開日 | 2011-03-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure and mechanism of Escherichia coli glutathionylspermidine amidase belonging to the family of cysteine; histidine-dependent amidohydrolases/peptidases
Protein Sci., 20, 2011
|
|
1EG0
 | | FITTING OF COMPONENTS WITH KNOWN STRUCTURE INTO AN 11.5 A CRYO-EM MAP OF THE E.COLI 70S RIBOSOME | | 分子名称: | FORMYL-METHIONYL-TRNA, FRAGMENT OF 16S RRNA HELIX 23, FRAGMENT OF 23S RRNA, ... | | 著者 | Gabashvili, I.S, Agrawal, R.K, Spahn, C.M.T, Grassucci, R.A, Svergun, D.I, Frank, J, Penczek, P. | | 登録日 | 2000-02-11 | | 公開日 | 2000-03-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | | 主引用文献 | Solution structure of the E. coli 70S ribosome at 11.5 A resolution.
Cell(Cambridge,Mass.), 100, 2000
|
|
7AH3
 | | Kinase domain of cSrc in complex with a pyrazolopyrimidine | | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Dello Iacono, L, Kleinboelting, S, Fallacara, A.L, Rauh, D. | | 登録日 | 2020-09-24 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Insights into the binding of pyrazolopyrimidines to Src kinase
To Be Published
|
|
6ZIP
 | | Crystal Structure of Two-Domain Laccase mutant R240A from Streptomyces griseoflavus | | 分子名称: | COPPER (II) ION, GLYCEROL, OXYGEN MOLECULE, ... | | 著者 | Gabdulkhakov, A.G, Tishchenko, T.V, Kolyadenko, I.A. | | 登録日 | 2020-06-26 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | The role of positive charged residue in the proton-transfer mechanism of two-domain laccase from Streptomyces griseoflavus Ac-993.
J.Biomol.Struct.Dyn., 40, 2022
|
|
6ZIJ
 | | Crystal Structure of Two-Domain Laccase mutant R240H from Streptomyces griseoflavus | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, GLYCEROL, ... | | 著者 | Gabdulkhakov, A.G, Tishchenko, T.V, Kolyadenko, I.A. | | 登録日 | 2020-06-26 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The role of positive charged residue in the proton-transfer mechanism of two-domain laccase from Streptomyces griseoflavus Ac-993.
J.Biomol.Struct.Dyn., 40, 2022
|
|
