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7DHJ
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The co-crystal structure of SARS-CoV-2 main protease with the peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pent-4-ynamide
分子名称: (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pent-4-ynamide, 3C-like proteinase
著者Shang, L.Q, Wang, H, Deng, W.L, Xing, S, Wang, Y.X.
登録日2020-11-15
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.962 Å)
主引用文献The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7DGF
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BU of 7dgf by Molmil
The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)hexanamide
分子名称: (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]hexanamide, 3C-like proteinase
著者Shang, L.Q, Wang, H.
登録日2020-11-11
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.639 Å)
主引用文献The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7DGG
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BU of 7dgg by Molmil
The co-crystal structure of SARS-CoV-2 main protease with (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)hexanamide
分子名称: (2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]hexanamide, 3C-like proteinase
著者Shang, L.Q, Wang, H.
登録日2020-11-11
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7DGI
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BU of 7dgi by Molmil
The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor N-((S)-3-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)amino)pentan-2-yl)amino)-1-oxobutan-2-yl)-4-nitrobenzamide
分子名称: 3C-like proteinase, ~{N}-[(2~{S})-3-methyl-1-[[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-4-nitro-benzamide
著者Shang, L.Q, Wang, H.
登録日2020-11-11
公開日2021-11-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.898 Å)
主引用文献The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate.
Eur.J.Med.Chem., 238, 2022
7VOP
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BU of 7vop by Molmil
Cryo-EM structure of Xenopus laevis nuclear pore complex cytoplasmic ring subunit
分子名称: GATOR complex protein SEC13, IL4I1 protein, MGC154553 protein, ...
著者Tai, L, Zhu, Y, Sun, F.
登録日2021-10-14
公開日2022-02-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献8 angstrom structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI.
Protein Cell, 13, 2022
7VCI
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Structure of Xenopus laevis NPC nuclear ring asymmetric unit
分子名称: GATOR complex protein SEC13, MGC154553 protein, MGC83295 protein, ...
著者Tai, L, Zhu, Y, Sun, F.
登録日2021-09-03
公開日2022-02-02
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (8.1 Å)
主引用文献8 angstrom structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI.
Protein Cell, 13, 2022
7Y9U
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BU of 7y9u by Molmil
Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the NPA-bound state
分子名称: 2-(naphthalen-1-ylcarbamoyl)benzoic acid, Auxin efflux carrier component 1, nanobody
著者Sun, L, Liu, X, Yang, Z, Xia, J.
登録日2022-06-26
公開日2022-09-07
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into auxin recognition and efflux by Arabidopsis PIN1.
Nature, 609, 2022
7Y9T
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Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the apo state
分子名称: Auxin efflux carrier component 1, nanobody
著者Sun, L, Liu, X, Yang, Z, Xia, J.
登録日2022-06-26
公開日2022-09-07
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into auxin recognition and efflux by Arabidopsis PIN1.
Nature, 609, 2022
3HO2
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BU of 3ho2 by Molmil
Structure of E.coli FabF(C163A) in complex with Platencin
分子名称: 2,4-dihydroxy-3-({3-[(2S,4aS,8S,8aR)-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonaphthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soisson, S.M, Parthasarathy, G.
登録日2009-06-01
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
6M3M
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BU of 6m3m by Molmil
Crystal structure of SARS-CoV-2 nucleocapsid protein N-terminal RNA binding domain
分子名称: Nucleoprotein
著者Chen, S, Kang, S.
登録日2020-03-04
公開日2020-03-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites.
Acta Pharm Sin B, 10, 2020
6JCA
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BU of 6jca by Molmil
Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in I222 space group
分子名称: CHLORIDE ION, CrmG, GLYCEROL, ...
著者Xu, J, Liu, J.
登録日2019-01-28
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition.
Commun Biol, 3, 2020
6JC8
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Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Glu
分子名称: (E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-glutamic acid, CrmG, GLYCEROL
著者Xu, J, Liu, J.
登録日2019-01-28
公開日2020-02-05
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition.
Commun Biol, 3, 2020
3I8P
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BU of 3i8p by Molmil
Crystal structure of E. coli FabF(C163A) in complex with Platensimycin A1
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, Platensimycin A1
著者Soisson, S.M, Parthsarathy, G.
登録日2009-07-09
公開日2010-07-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3HO9
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BU of 3ho9 by Molmil
Structure of E.coli FabF(C163A) in complex with Platencin A1
分子名称: 2,4-dihydroxy-3-({3-[(2R,4aR,8S,8aR,9R)-9-hydroxy-8-methyl-3-methylidene-7-oxo-1,3,4,7,8,8a-hexahydro-2H-2,4a-ethanonap hthalen-8-yl]propanoyl}amino)benzoic acid, 3-oxoacyl-[acyl-carrier-protein] synthase 2
著者Soisson, S.M, Parthasarathy, G.
登録日2009-06-01
公開日2010-02-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
3HNZ
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BU of 3hnz by Molmil
Structure of E. coli FabF(C163A) in Complex with Platensimycin
分子名称: 3-oxoacyl-[acyl-carrier-protein] synthase 2, PLATENSIMYCIN
著者Soisson, S.M, Parthasarathy, G.
登録日2009-06-01
公開日2010-02-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Isolation, enzyme-bound structure and antibacterial activity of platencin A1 from Streptomyces platensis.
Bioorg.Med.Chem.Lett., 19, 2009
2L6G
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BU of 2l6g by Molmil
FAT-LD2 Double labeled construct with free LD4 peptide
分子名称: Focal adhesion kinase 1, linker, Paxillin
著者Bertolucci, C.M, Guibao, C, Zhang, C, Zheng, J.
登録日2010-11-19
公開日2012-05-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Fat-Ld2 Double Labeled Construct with Free Ld4 Peptide
To be Published
7WK5
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BU of 7wk5 by Molmil
Cryo-EM structure of Omicron S-ACE2, C2 state
分子名称: Angiotensin-converting enzyme 2, Spike glycoprotein
著者Han, W.Y, Wang, Y.F.
登録日2022-01-08
公開日2022-02-02
最終更新日2022-03-09
実験手法ELECTRON MICROSCOPY (3.66 Å)
主引用文献Molecular basis of SARS-CoV-2 Omicron variant receptor engagement and antibody evasion and neutralization
Biorxiv, 2022
7WK3
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BU of 7wk3 by Molmil
SARS-CoV-2 Omicron S-open
分子名称: Spike glycoprotein
著者Li, J.W, Cong, Y.
登録日2022-01-08
公開日2022-01-26
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for ACE2 engagement and antibody evasion and neutralization of SARS-Co-2 Omicron varient
To Be Published
6BL9
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BU of 6bl9 by Molmil
NMR Solution structure of U-SLPTX15-Sm2a
分子名称: Sm2a toxin
著者Harvey, P.J, Craik, D.J, Durek, T, Dash, T.J.
登録日2017-11-09
公開日2018-11-14
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献A Centipede Toxin Family Defines an Ancient Class of CS alpha beta Defensins.
Structure, 27, 2019
3NPZ
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BU of 3npz by Molmil
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
分子名称: Prolactin, Prolactin receptor
著者Van Agthoven, J, England, P, Goffin, V, Broutin, I.
登録日2010-06-29
公開日2010-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone.
J.Mol.Biol., 404, 2010
4GJT
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BU of 4gjt by Molmil
complex structure of nectin-4 bound to MV-H
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4
著者Zhang, X, Lu, G, Qi, J, Li, Y, He, Y, Xu, X, Shi, J, Zhang, C, Yan, J, Gao, G.F.
登録日2012-08-10
公開日2012-10-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.1001 Å)
主引用文献Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
7XKE
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BU of 7xke by Molmil
Cryo-EM structure of DHEA-ADGRG2-FL-Gs complex
分子名称: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
登録日2022-04-19
公開日2022-08-10
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
Nat.Chem.Biol., 18, 2022
7XKF
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Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex at lower state
分子名称: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
登録日2022-04-19
公開日2022-08-10
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
Nat.Chem.Biol., 18, 2022
7XKD
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BU of 7xkd by Molmil
Cryo-EM structure of DHEA-ADGRG2-BT-Gs complex
分子名称: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, Adhesion G-protein coupled receptor G2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Guo, S.C, Xiao, P, Lin, H, Sun, J.P, Yu, X.
登録日2022-04-19
公開日2022-08-10
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structures of the ADGRG2-G s complex in apo and ligand-bound forms.
Nat.Chem.Biol., 18, 2022
3N94
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Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain
分子名称: Fusion protein of Maltose-binding periplasmic protein and pituitary adenylate cyclase 1 Receptor-short, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Kumar, S, Pioszak, A.A, Swaminathan, K, Xu, H.E.
登録日2010-05-28
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors.
Plos One, 6, 2011

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