Search by PDB author

Cryo-EM structure of human urea transporter A2.
分子名称:	1-(3-methoxyphenyl)methanamine, 8-hydroxyquinoline-2-carboxylic acid, Urea transporter 2
著者	Huang, S, Liu, L, Sun, J.
登録日	2023-12-10
公開日	2024-12-04
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters. Nat Commun, 15, 2024

2J5F

Crystal structure of EGFR kinase domain in complex with an irreversible inhibitor 34-jab
分子名称:	EPIDERMAL GROWTH FACTOR RECEPTOR, N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE
著者	Yun, C.-H, Eck, M.J.
登録日	2006-09-14
公開日	2007-02-27
最終更新日	2024-11-13
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Structure-Guided Development of Affinity Probes for Tyrosine Kinases Using Chemical Genetics. Nat.Chem.Biol., 3, 2007

7WUJ

Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4
分子名称:	Adhesion G-protein coupled receptor G4,Uncharacterized protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Guo, S.C, Huang, S.M, He, Q.T, Xiao, P, Sun, J.P, Yu, X.
登録日	2022-02-08
公開日	2022-04-27
最終更新日	2024-11-13
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604, 2022

7M8W

XFEL crystal structure of the prostaglandin D2 receptor CRTH2 in complex with 15R-methyl-PGD2
分子名称:	15R-methyl-prostaglandin D2, CITRATE ANION, Prostaglandin D2 receptor 2, ...
著者	Shiriaeva, A, Han, G.W, Cherezov, V.
登録日	2021-03-30
公開日	2021-08-25
最終更新日	2023-10-18
実験手法	X-RAY DIFFRACTION (2.61 Å)
主引用文献	Molecular basis for lipid recognition by the prostaglandin D 2 receptor CRTH2. Proc.Natl.Acad.Sci.USA, 118, 2021

2J5E

Crystal structure of EGFR kinase domain in complex with an irreversible inhibitor 13-jab
分子名称:	CHLORIDE ION, EPIDERMAL GROWTH FACTOR RECEPTOR
著者	Yun, C.-H, Eck, M.J.
登録日	2006-09-14
公開日	2007-02-27
最終更新日	2023-12-13
実験手法	X-RAY DIFFRACTION (3.1 Å)
主引用文献	Structure-Guided Development of Affinity Probes for Tyrosine Kinases Using Chemical Genetics. Nat.Chem.Biol., 3, 2007

7VKK

Crystal structure of D. melanogaster SAMTOR V66W/E67P mutant
分子名称:	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-adenosylmethionine sensor upstream of mTORC1, SULFATE ION
著者	Zhang, T, Ding, J.
登録日	2021-09-30
公開日	2022-07-20
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (3.55 Å)
主引用文献	Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling. Sci Adv, 8, 2022

7VKR

Crystal structure of D. melanogaster SAMTOR in complex with SAM
分子名称:	CITRIC ACID, S-ADENOSYLMETHIONINE, S-adenosylmethionine sensor upstream of mTORC1
著者	Tang, X, Zhang, T, Ding, J.
登録日	2021-09-30
公開日	2022-07-20
最終更新日	2024-11-13
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling. Sci Adv, 8, 2022

7VKQ

Crystal structure of D. melanogaster SAMTOR in the SAH bound form
分子名称:	S-ADENOSYL-L-HOMOCYSTEINE, S-adenosylmethionine sensor upstream of mTORC1
著者	Tang, X, Zhang, T, Ding, J.
登録日	2021-09-30
公開日	2022-07-20
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.094 Å)
主引用文献	Molecular mechanism of S -adenosylmethionine sensing by SAMTOR in mTORC1 signaling. Sci Adv, 8, 2022

5TUH

Archaellum periplasmic stator protein FlaG from Sulfolobus acidocaldarius
分子名称:	Flagellar biosynthesis protein FlaG, GLYCEROL
著者	Tsai, C.-L, Tainer, J.A.
登録日	2016-11-06
公開日	2018-01-10
最終更新日	2024-03-06
実験手法	X-RAY DIFFRACTION (1.929 Å)
主引用文献	The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility. Nat Microbiol, 5, 2020

7WUI

Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4
分子名称:	Adhesion G-protein coupled receptor G2,mCherry, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ...
著者	Guo, S.C, He, Q.T, Xiao, P, Sun, J.P, Yu, X.
登録日	2022-02-08
公開日	2022-04-27
最終更新日	2024-11-13
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4. Nature, 604, 2022

5TUG

Archaellum periplasmic stator protein complex FlaF and FlaG from Sulfolobus acidocaldarius
分子名称:	1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Flagellar biosynthesis protein FlaF, ...
著者	Tsai, C.-L, Tainer, J.A.
登録日	2016-11-06
公開日	2018-01-10
最終更新日	2023-10-04
実験手法	X-RAY DIFFRACTION (2.47 Å)
主引用文献	The structure of the periplasmic FlaG-FlaF complex and its essential role for archaellar swimming motility. Nat Microbiol, 5, 2020

6IPP

Non-native ferritin 8-mer mutant-C90A/C102A/C130A/D144C
分子名称:	FE (III) ION, Ferritin heavy chain
著者	Zang, J, Chen, H, Zhou, K, Zhao, G.
登録日	2018-11-03
公開日	2019-03-13
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.699 Å)
主引用文献	Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages. Nat Commun, 10, 2019

6JC7

Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Ala
分子名称:	(E)-N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-alanine, ACETIC ACID, CrmG, ...
著者	Xu, J, Su, K, Liu, J.
登録日	2019-01-28
公開日	2020-02-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition. Commun Biol, 3, 2020

8XKN

Cryo-EM structure of tail tube protein
分子名称:	a protein
著者	Zhang, H, Li, Z, Li, X.Z.
登録日	2023-12-23
公開日	2024-05-01
最終更新日	2024-05-08
実験手法	ELECTRON MICROSCOPY (3.11 Å)
主引用文献	Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024

6JC9

Crystal structure of aminotransferase CrmG from Actinoalloteichus sp. WH1-2216-6 in complex with amino donor L-Gln
分子名称:	ACETIC ACID, CrmG, GLUTAMINE, ...
著者	Xu, J, Liu, J.
登録日	2019-01-28
公開日	2020-02-05
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Structural studies reveal flexible roof of active site responsible for omega-transaminase CrmG overcoming by-product inhibition. Commun Biol, 3, 2020

6JLC

Structure determination of CAMP factor of Mobiluncus curtisii and insight into structural dynamics
分子名称:	ACETATE ION, CAMP factor
著者	Jin, T.C, Zeng, W.H.
登録日	2019-03-04
公開日	2019-12-04
最終更新日	2023-11-22
実験手法	X-RAY DIFFRACTION (1.847 Å)
主引用文献	Structure determination of CAMP factor of Mobiluncus curtisii and insights into structural dynamics. Int.J.Biol.Macromol., 150, 2020

7DGB

The co-crystal structure of SARS-CoV-2 main protease with (S)-2-cinnamamido-4-methyl-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pentanamide
分子名称:	(2~{S})-4-methyl-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pentanamide, 3C-like proteinase
著者	Shang, L.Q, Wang, H.
登録日	2020-11-11
公開日	2021-11-24
最終更新日	2024-10-30
実験手法	X-RAY DIFFRACTION (1.678 Å)
主引用文献	The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022

7DGH

The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor N-((S)-3-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)amino)pentan-2-yl)amino)-1-oxobutan-2-yl)-2-naphthamide
分子名称:	3C-like proteinase, ~{N}-[(2~{S})-3-methyl-1-[[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]naphthalene-2-carboxamide
著者	Shang, L.Q, Wang, H.
登録日	2020-11-11
公開日	2021-11-24
最終更新日	2024-11-06
実験手法	X-RAY DIFFRACTION (1.968 Å)
主引用文献	The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022

7DGF

The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)hexanamide
分子名称:	(2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]hexanamide, 3C-like proteinase
著者	Shang, L.Q, Wang, H.
登録日	2020-11-11
公開日	2021-11-24
最終更新日	2024-11-13
実験手法	X-RAY DIFFRACTION (1.639 Å)
主引用文献	The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022

7DGG

The co-crystal structure of SARS-CoV-2 main protease with (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)hexanamide
分子名称:	(2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]hexanamide, 3C-like proteinase
著者	Shang, L.Q, Wang, H.
登録日	2020-11-11
公開日	2021-11-24
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (2.004 Å)
主引用文献	The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022

7DGI

The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor N-((S)-3-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)amino)pentan-2-yl)amino)-1-oxobutan-2-yl)-4-nitrobenzamide
分子名称:	3C-like proteinase, ~{N}-[(2~{S})-3-methyl-1-[[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-4-nitro-benzamide
著者	Shang, L.Q, Wang, H.
登録日	2020-11-11
公開日	2021-11-24
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (1.898 Å)
主引用文献	The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022

7DHJ

The co-crystal structure of SARS-CoV-2 main protease with the peptidomimetic inhibitor (S)-2-cinnamamido-N-((S)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)pent-4-ynamide
分子名称:	(2~{S})-~{N}-[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[(~{E})-3-phenylprop-2-enoyl]amino]pent-4-ynamide, 3C-like proteinase
著者	Shang, L.Q, Wang, H, Deng, W.L, Xing, S, Wang, Y.X.
登録日	2020-11-15
公開日	2021-11-24
最終更新日	2024-11-06
実験手法	X-RAY DIFFRACTION (1.962 Å)
主引用文献	The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022

6IPQ

Non-native ferritin 8-mer mutant-C90A/C102A/C130A
分子名称:	Ferritin heavy chain, MAGNESIUM ION
著者	Zang, J, Chen, H, Wang, Y, Zhao, G.
登録日	2018-11-03
公開日	2019-03-13
最終更新日	2024-03-27
実験手法	X-RAY DIFFRACTION (3.103 Å)
主引用文献	Disulfide-mediated conversion of 8-mer bowl-like protein architecture into three different nanocages. Nat Commun, 10, 2019

8EWG

Cryo-EM structure of a riboendonclease
分子名称:	CRISPR-associated endonuclease Cas9, RNA (56-MER)
著者	Li, Z, Wang, F.
登録日	2022-10-23
公開日	2023-08-30
最終更新日	2025-05-21
実験手法	ELECTRON MICROSCOPY (2.9 Å)
主引用文献	Structural Basis for the Ribonuclease Activity of a Thermostable CRISPR-Cas13a from Thermoclostridium caenicola. J.Mol.Biol., 435, 2023

5F9P

Crystal structure study of anthrone oxidase-like protein
分子名称:	Anthrone oxidase-like protein, GLYCEROL
著者	Gao, X, Wu, D, Fan, K, Liu, Z.-J.
登録日	2015-12-10
公開日	2016-12-14
最終更新日	2024-10-23
実験手法	X-RAY DIFFRACTION (2.078 Å)
主引用文献	Structure and Function of a C-C Bond Cleaving Oxygenase in Atypical Angucycline Biosynthesis ACS Chem. Biol., 12, 2017

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