7M8W

XFEL crystal structure of the prostaglandin D2 receptor CRTH2 in complex with 15R-methyl-PGD2

Summary for 7M8W

Entry DOI	10.2210/pdb7m8w/pdb
Descriptor	Prostaglandin D2 receptor 2, Endolysin chimera, 15R-methyl-prostaglandin D2, SODIUM ION, ... (6 entities in total)
Functional Keywords	prostaglandin d2 receptor, crth2, 15r-methyl-pgd2, g protein-coupled receptor, gpcr, endolysin fusion, membrane protein, lcp
Biological source	Homo sapiens (Human) More
Total number of polymer chains	1
Total formula weight	53287.62
Authors	Shiriaeva, A.,Han, G.W.,Cherezov, V. (deposition date: 2021-03-30, release date: 2021-08-25, Last modification date: 2023-10-18)
Primary citation	Liu, H.,Deepak, R.N.V.K.,Shiriaeva, A.,Gati, C.,Batyuk, A.,Hu, H.,Weierstall, U.,Liu, W.,Wang, L.,Cherezov, V.,Fan, H.,Zhang, C. Molecular basis for lipid recognition by the prostaglandin D 2 receptor CRTH2. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 34341104 DOI: 10.1073/pnas.2102813118 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.61 Å)

Structure validation