4MS9
| Native RNA-10mer Structure: ccggcgccgg | 分子名称: | Native RNA duplex 10mer, STRONTIUM ION | 著者 | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | 登録日 | 2013-09-18 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Structural insights into the effects of 2'-5' linkages on the RNA duplex. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MSB
| RNA 10mer duplex with two 2'-5'-linkages | 分子名称: | RNA 10mer duplex with two 2'-5'-linkages, STRONTIUM ION | 著者 | Sheng, J, Li, L, Engelhart, A.E, Gan, J, Wang, J, Szostak, J.W. | 登録日 | 2013-09-18 | 公開日 | 2014-02-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural insights into the effects of 2'-5' linkages on the RNA duplex. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
5XP8
| Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 4A5 on the guide strand | 分子名称: | DNA (5'-D(*AP*GP*T)-3'), DNA (5'-D(*CP*AP*AP*CP*C*AP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(P*TP*GP*AP*GP*AP*GP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*T)-3'), ... | 著者 | Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, J.D, Wang, Y. | 登録日 | 2017-06-01 | 公開日 | 2018-04-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Res., 45, 2017
|
|
5XQ2
| Crystal structure of T. thermophilus Argonaute protein complexed with a bulge 5A6 on the guide strand | 分子名称: | DNA (5'-D(*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*CP*G)-3'), DNA (5'-D(*AP*GP*T)-3'), DNA (5'-D(P*TP*GP*AP*AP*GP*AP*TP*AP*GP*TP*AP*GP*GP*TP*TP*GP*T)-3'), ... | 著者 | Sheng, G, Gogakos, T, Wang, J, Zhao, H, Serganov, A, Juranek, S, Tuschl, T, Patel, D, Wang, Y. | 登録日 | 2017-06-06 | 公開日 | 2017-10-04 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes Nucleic Acids Res., 45, 2017
|
|
1FXP
| AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH CADMIUM | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, PHOSPHATE ION | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | 登録日 | 2000-09-26 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
|
|
1FX6
| AQUIFEX AEOLICUS KDO8P SYNTHASE | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, PHOSPHATE ION | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | 登録日 | 2000-09-25 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
|
|
1FY6
| AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH CADMIUM AND A5P | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, CADMIUM ION, ... | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | 登録日 | 2000-09-28 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
|
|
1FXQ
| AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP AND A5P | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, ARABINOSE-5-PHOSPHATE, PHOSPHOENOLPYRUVATE | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | 登録日 | 2000-09-26 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
|
|
1FWT
| AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP, E4P AND CADMIUM | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, CADMIUM ION, ERYTHOSE-4-PHOSPHATE, ... | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | 登録日 | 2000-09-24 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
|
|
1FWN
| AQUIFEX AEOLICUS KDO8P SYNTHASE IN COMPLEX WITH PEP | 分子名称: | 2-DEHYDRO-3-DEOXYPHOSPHOOCTONATE ALDOLASE, PHOSPHATE ION, PHOSPHOENOLPYRUVATE | 著者 | Duewel, H.S, Radaev, S, Wang, J, Woodard, R.W, Gatti, D.L. | 登録日 | 2000-09-23 | 公開日 | 2001-04-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Substrate and metal complexes of 3-deoxy-D-manno-octulosonate-8-phosphate synthase from Aquifex aeolicus at 1.9-A resolution. Implications for the condensation mechanism. J.Biol.Chem., 276, 2001
|
|
5YEL
| Crystal structure of CTCF ZFs6-11-gb7CSE | 分子名称: | DNA (26-MER), Transcriptional repressor CTCF, ZINC ION | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-18 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.96 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
|
|
7F6W
| Crystal structure of Saccharomyces cerevisiae lysyl-tRNA Synthetase | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 5'-O-[(L-LYSYLAMINO)SULFONYL]ADENOSINE, Lysine--tRNA ligase | 著者 | Wu, S, Li, P, Hei, Z, Zheng, L, Wang, J, Fang, P. | 登録日 | 2021-06-26 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.607 Å) | 主引用文献 | Human lysyl-tRNA synthetase evolves a dynamic structure that can be stabilized by forming complex. Cell.Mol.Life Sci., 79, 2022
|
|
5YEH
| Crystal structure of CTCF ZFs4-8-eCBS | 分子名称: | DNA (5'-D(*AP*CP*GP*GP*TP*TP*TP*CP*CP*GP*CP*TP*AP*GP*AP*GP*GP*GP*CP*G)-3'), DNA (5'-D(*TP*CP*GP*CP*CP*CP*TP*CP*TP*AP*GP*CP*GP*GP*AP*AP*AP*CP*CP*G)-3'), Transcriptional repressor CTCF, ... | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-17 | 公開日 | 2017-11-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.328 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
|
|
5YEF
| Crystal structure of CTCF ZFs2-8-Hs5-1aE | 分子名称: | DNA (27-MER), Transcriptional repressor CTCF, ZINC ION | 著者 | Yin, M, Wang, J, Wang, M, Li, X, Wang, Y. | 登録日 | 2017-09-17 | 公開日 | 2017-11-29 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.807 Å) | 主引用文献 | Molecular mechanism of directional CTCF recognition of a diverse range of genomic sites Cell Res., 27, 2017
|
|
3PS4
| PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, Microtubule-associated serine/threonine-protein kinase 1 | 著者 | Ugochukwu, E, Wang, J, Krojer, T, Muniz, J.R.C, Sethi, R, Pike, A.C.W, Roos, A, Salah, E, Cocking, R, Savitsky, P, Doyle, D.A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-30 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 TO BE PUBLISHED
|
|
2GF9
| Crystal structure of human RAB3D in complex with GDP | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein Rab-3D, ... | 著者 | Hong, B, Wang, J, Shen, L, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-03-21 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | Crystal structure of human RAB3D in complex with GDP To be Published
|
|
5ZM7
| Crystal structure of ORP1-ORD in complex with cholesterol at 3.4 A resolution | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | 著者 | Dong, J, Wang, J, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.401 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
|
|
5ZM6
| Crystal structure of ORP1-ORD in complex with PI(4,5)P2 | 分子名称: | ACETATE ION, Oxysterol-binding protein-related protein 1, [(2~{S})-1-octadecanoyloxy-3-[oxidanyl-[(1~{R},2~{R},3~{S},4~{S},5~{S},6~{S})-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propan-2-yl] icosa-5,8,11,14-tetraenoate | 著者 | Dong, J, Wang, J, Luo, Z, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
|
|
2HEI
| Crystal structure of human RAB5B in complex with GDP | 分子名称: | (4S,5S)-1,2-DITHIANE-4,5-DIOL, GUANOSINE-5'-DIPHOSPHATE, Ras-related protein Rab-5B | 著者 | Hong, B, Shen, L, Wang, J, Tempel, W, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2006-06-21 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of human RAB5B in complex with GDP To be Published
|
|
5ZM5
| Crystal structure of human ORP1-ORD in complex with cholesterol at 2.6 A resolution | 分子名称: | CHOLESTEROL, Oxysterol-binding protein-related protein 1 | 著者 | Dong, J, Wang, J, Wu, J.W. | 登録日 | 2018-04-01 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P2/PI(3,4)P2. Nat Commun, 10, 2019
|
|
2O9Q
| The crystal structure of Bovine Trypsin complexed with a small inhibition peptide ORB2K | 分子名称: | CALCIUM ION, Cationic trypsin, ORB2K, ... | 著者 | Li, J, Zhang, C, Xu, X, Wang, J, Gong, W, Lai, R. | 登録日 | 2006-12-14 | 公開日 | 2007-12-25 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | From protease inhibitor to antibiotics: single point mutation makes tremendous functional shift To be Published
|
|
6LOX
| Crystal Structure of human glutaminase with macrocyclic inhibitor | 分子名称: | (E)-15,22-Dioxa-4,11-diaza-5(2,5)-thiadiazola-10(3,6)-pyridazina-1,14(1,3)-dibenzenacyclodocosaphan-18-ene-3,12-dione, Glutaminase kidney isoform, mitochondrial | 著者 | Bian, J, Li, Z, Xu, X, Wang, J, Li, L. | 登録日 | 2020-01-07 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site. J.Med.Chem., 64, 2021
|
|
6C6F
| |
6IFL
| Cryo-EM structure of type III-A Csm-NTR complex | 分子名称: | NTR, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-20 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.16 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|
6IFY
| Type III-A Csm complex, Cryo-EM structure of Csm-CTR1 | 分子名称: | CTR1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ... | 著者 | You, L, Ma, J, Wang, J, Zhang, X, Wang, Y. | 登録日 | 2018-09-21 | 公開日 | 2018-12-12 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference Cell, 176, 2019
|
|