3S6B
 
 | | Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150 | | 分子名称: | FE (III) ION, GLYCEROL, Methionine aminopeptidase | | 著者 | Wernimont, A.K, Artz, J.D, Crombet, L, Lew, J, Weadge, J, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Hui, R, Hills, T, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-25 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150
To be Published
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3S92
 | | Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1 | | 分子名称: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, 1,2-ETHANEDIOL, Bromodomain-containing protein 3 | | 著者 | Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-31 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Crystal Structure of the second bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
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3SMT
 | | Crystal structure of human SET domain-containing protein3 | | 分子名称: | ACETATE ION, ARSENIC, Histone-lysine N-methyltransferase setd3, ... | | 著者 | Dong, A, Zeng, H, Walker, J.R, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-06-28 | | 公開日 | 2011-07-20 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Crystal structure of human SET domain-containing protein3
To be Published
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3SVG
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand | | 分子名称: | (1R)-1-[3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-ethoxyphenyl]ethanol, 1,2-ETHANEDIOL, Bromodomain-containing protein 4 | | 著者 | Filippakopoulos, P, Picaud, S, Felletar, I, Hewings, S.D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Conway, S.J, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-07-12 | | 公開日 | 2011-08-10 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
TO BE PUBLISHED
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3S91
 | | Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1 | | 分子名称: | (6S)-6-(2-tert-butoxy-2-oxoethyl)-4-(4-chlorophenyl)-2,3,9-trimethyl-6,7-dihydrothieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-10-ium, Bromodomain-containing protein 3, ISOPROPYL ALCOHOL | | 著者 | Filippakopoulos, P, Picaud, S, Qi, J, Keates, T, Felletar, I, Fedorov, O, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Bradner, J.E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-31 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | Crystal Structure of the first bromodomain of human BRD3 in complex with the inhibitor JQ1
To be Published
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3S4Y
 | | Crystal structure of human thiamin pyrophosphokinase 1 | | 分子名称: | CALCIUM ION, SULFATE ION, THIAMINE DIPHOSPHATE, ... | | 著者 | Shen, L, Tempel, W, Tong, Y, Li, Y, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-20 | | 公開日 | 2011-06-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of human thiamin pyrophosphokinase 1
to be published
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3SN5
 | | Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one | | 分子名称: | (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Strushkevich, N, Tempel, W, MacKenzie, F, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-06-28 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one
To be Published
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3S95
 | | Crystal structure of the human LIMK1 kinase domain in complex with staurosporine | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | | 著者 | Beltrami, A, Chaikuad, A, Daga, N, Elkins, J.M, Mahajan, P, Savitsky, P, Vollmar, M, Krojer, T, Muniz, J.R.C, Fedorov, O, Allerston, C.K, Yue, W.W, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Bullock, A, Structural Genomics Consortium (SGC) | | 登録日 | 2011-05-31 | | 公開日 | 2011-07-06 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structure of the human LIMK1 kinase domain in complex with staurosporine
To be Published
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3UOW
 | | Crystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum | | 分子名称: | CALCIUM ION, GMP synthetase, XANTHOSINE-5'-MONOPHOSPHATE | | 著者 | Wernimont, A.K, Dong, A, Hills, T, Amani, M, Perieteanu, A, Lin, Y.H, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Hui, R, Structural Genomics Consortium (SGC) | | 登録日 | 2011-11-17 | | 公開日 | 2011-12-07 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Crystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum
TO BE PUBLISHED
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3UT1
 | | Crystal structure of the 3-MBT repeat domain of L3MBTL3 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, Lethal(3)malignant brain tumor-like protein 3, ... | | 著者 | Zhong, N, Tempel, W, Wernimont, A.K, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) | | 登録日 | 2011-11-24 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of the 3-MBT repeat domain of L3MBTL3
to be published
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3V6C
 | | Crystal Structure of USP2 in complex with mutated ubiquitin | | 分子名称: | CHLORIDE ION, GLYCEROL, Ubiquitin, ... | | 著者 | Neculai, M, Ernst, A, Sidhu, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-12-19 | | 公開日 | 2012-12-19 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal Structure of USP2 in complex with mutated ubiquitin
To be Published
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3V8D
 | | Crystal structure of human CYP7A1 in complex with 7-ketocholesterol | | 分子名称: | (3beta,8alpha,9beta)-3-hydroxycholest-5-en-7-one, Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Strushkevich, N, Tempel, W, MacKenzie, F, Wernimont, A.K, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Usanov, S.A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2011-12-22 | | 公開日 | 2013-01-09 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of human CYP7A1 in complex with 7-ketocholesterol
To be Published
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3U12
 | | The pleckstrin homology (PH) domain of USP37 | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, SULFATE ION, ... | | 著者 | Dong, A, Nair, U.B, Wernimont, A, Walker, J.R, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-09-29 | | 公開日 | 2011-11-09 | | 最終更新日 | 2012-05-02 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | The pleckstrin homology (PH) domain of USP37
To be Published
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6FDY
 | | Unc-51-Like Kinase 3 (ULK3) In Complex With Bosutinib | | 分子名称: | 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile, Serine/threonine-protein kinase ULK3 | | 著者 | Mathea, S, Salah, E, Moroglu, M, Scorah, A, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K, Knapp, S. | | 登録日 | 2017-12-27 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Unc-51-Like Kinase 3 (ULK3) In Complex With Bosutinib
To Be Published
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6FDZ
 | | Unc-51-Like Kinase 3 (ULK3) In Complex With Momelotinib | | 分子名称: | Momelotinib, Serine/threonine-protein kinase ULK3 | | 著者 | Mathea, S, Salah, E, Moroglu, M, Scorah, A, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Huber, K, Knapp, S. | | 登録日 | 2017-12-27 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Unc-51-Like Kinase 3 (ULK3) In Complex With Momelotinib
To Be Published
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3C5C
 | | Crystal structure of human Ras-like, family 12 protein in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-like protein 12, ... | | 著者 | Shen, L, Tong, Y, Tempel, W, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-01-31 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of human Ras-like, family 12 protein in complex with GDP.
To be Published
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3DLJ
 | | Crystal structure of human carnosine dipeptidase 1 | | 分子名称: | Beta-Ala-His dipeptidase, SULFATE ION, UNKNOWN ATOM OR ION, ... | | 著者 | Dong, A, Dobrovetsky, E, Seitova, A, He, H, Tempel, W, Kozieradzki, I, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Bochkarev, A, Cossar, D, Structural Genomics Consortium (SGC) | | 登録日 | 2008-06-27 | | 公開日 | 2008-08-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal structure of human carnosine dipeptidase 1.
To be Published
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3DLX
 | | Crystal structure of human 3-oxoacid CoA transferase 1 | | 分子名称: | GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase 1 | | 著者 | Kavanagh, K.L, Shafqat, N, Yue, W.W, Picaud, S, Murray, J.W, Maclean, E.M, von Delft, F, Roos, A.K, Arrowsmith, C.H, Wikstrom, M, Edwards, A.M, Bountra, C, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2008-06-30 | | 公開日 | 2008-08-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of human 3-oxoacid CoA transferase 1.
To be Published
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3EDT
 | | Crystal structure of the mutated S328N hKLC2 TPR domain | | 分子名称: | Kinesin light chain 2, UNKNOWN ATOM OR ION | | 著者 | Zhu, H, Shen, Y, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-03 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of mutated S328N TPR domain of human kinesin light chain 2
To be published
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3EPP
 | | Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin | | 分子名称: | SINEFUNGIN, mRNA cap guanine-N7 methyltransferase | | 著者 | Amaya, M.F, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-29 | | 公開日 | 2008-10-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal structure of mRNA cap guanine-N7 methyltransferase (RNMT) in complex with sinefungin.
To be Published
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3E95
 | | Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a | | 分子名称: | UNKNOWN ATOM OR ION, Ubiquitin carrier protein, Ubiquitin-conjugating enzyme E2 | | 著者 | Wernimont, A.K, Lam, A, Ali, A, Brokx, S, Lin, Y.H, Zhao, Y, Lew, J, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Wilkstrom, M, BOuntra, C, Arrowsmith, C.H, Edwards, A.M, Hui, R, Qiu, W, Brand, V.B, Structural Genomics Consortium (SGC) | | 登録日 | 2008-08-21 | | 公開日 | 2008-09-30 | | 最終更新日 | 2017-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structure of the Plasmodium Falciparum ubiquitin conjugating enzyme complex, PfUBC13-PfUev1a
TO BE PUBLISHED
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3EAP
 | | Crystal structure of the RhoGAP domain of ARHGAP11A | | 分子名称: | Rho GTPase-activating protein 11A, UNKNOWN ATOM OR ION | | 著者 | Shen, Y, Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium, Structural Genomics Consortium (SGC) | | 登録日 | 2008-08-26 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the RhoGAP domain of ARHGAP11A
To be Published
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3EPY
 | | Crystal Structure of human acyl-CoA binding domain 7 complexed with palmitoyl-Coa | | 分子名称: | Acyl-CoA-binding domain-containing protein 7, COENZYME A, PALMITIC ACID | | 著者 | Kavanagh, K.L, Salah, E, Yue, W.W, Savitsky, P, Murray, J.W, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Bountra, C, von Delft, F, Oppermann, U, Structural Genomics Consortium (SGC) | | 登録日 | 2008-09-30 | | 公開日 | 2009-01-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.005 Å) | | 主引用文献 | Crystal Structure of human acyl-CoA binding domain 7 complexed with palmitoyl-Coa
To be Published
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3EBQ
 | | Crystal structure of human PPPDE1 | | 分子名称: | MERCURY (II) ION, MOLECULE: PPPDE1 (PERMUTED PAPAIN FOLD PEPTIDASES OF DSRNA VIRUSES AND EUKARYOTES 1), UPF0326 protein FAM152B | | 著者 | Walker, J.R, Akutsu, M, Qiu, L, Li, Y, Slessarev, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | 登録日 | 2008-08-28 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of Human PPPDE1
To be Published
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3CBQ
 | | Crystal structure of the human REM2 GTPase with bound GDP | | 分子名称: | 1,2-ETHANEDIOL, GTP-binding protein REM 2, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Nedyalkova, L, Shen, Y, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | | 登録日 | 2008-02-22 | | 公開日 | 2008-03-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Crystal structure of the human REM2 GTPase with bound GDP.
To be Published
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