3V8D

Crystal structure of human CYP7A1 in complex with 7-ketocholesterol

Summary for 3V8D

• Entry DOI: 10.2210/pdb3v8d/pdb
• Descriptor: Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, (3beta,8alpha,9beta)-3-hydroxycholest-5-en-7-one, ... (6 entities in total)
• Functional Keywords: cytochrome, oxidoreductase, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum membrane; Peripheral membrane protein: P22680
• Total number of polymer chains: 2
• Total formula weight: 115574.30

Authors

Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Usanov, S.A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2011-12-22, release date: 2013-01-09, Last modification date: 2023-09-13)

• Primary citation: Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Usanov, S.A.,Park, H.; Crystal structure of human CYP7A1 in complex with 7-ketocholesterol; To be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)