3S95

Crystal structure of the human LIMK1 kinase domain in complex with staurosporine

Summary for 3S95

• Entry DOI: 10.2210/pdb3s95/pdb
• Descriptor: LIM domain kinase 1, STAUROSPORINE, SODIUM ION, ... (8 entities in total)
• Functional Keywords: structural genomics, structural genomics consortium, sgc, protein kinase, lim domain kinase, transferase-antibiotic complex, transferase/antibiotic
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P53667
• Total number of polymer chains: 2
• Total formula weight: 74414.99

Authors

Beltrami, A.,Chaikuad, A.,Daga, N.,Elkins, J.M.,Mahajan, P.,Savitsky, P.,Vollmar, M.,Krojer, T.,Muniz, J.R.C.,Fedorov, O.,Allerston, C.K.,Yue, W.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2011-05-31, release date: 2011-07-06, Last modification date: 2023-09-13)

• Primary citation: Beltrami, A.,Chaikuad, A.,Daga, N.,Elkins, J.M.,Mahajan, P.,Savitsky, P.,Vollmar, M.,Krojer, T.,Muniz, J.R.C.,Fedorov, O.,Allerston, C.K.,Yue, W.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.; Crystal structure of the human LIMK1 kinase domain in complex with staurosporine; To be Published,

Experimental method

X-RAY DIFFRACTION (1.65 Å)