3S95
Crystal structure of the human LIMK1 kinase domain in complex with staurosporine
Summary for 3S95
Entry DOI | 10.2210/pdb3s95/pdb |
Descriptor | LIM domain kinase 1, STAUROSPORINE, SODIUM ION, ... (8 entities in total) |
Functional Keywords | structural genomics, structural genomics consortium, sgc, protein kinase, lim domain kinase, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P53667 |
Total number of polymer chains | 2 |
Total formula weight | 74414.99 |
Authors | Beltrami, A.,Chaikuad, A.,Daga, N.,Elkins, J.M.,Mahajan, P.,Savitsky, P.,Vollmar, M.,Krojer, T.,Muniz, J.R.C.,Fedorov, O.,Allerston, C.K.,Yue, W.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A.,Structural Genomics Consortium (SGC) (deposition date: 2011-05-31, release date: 2011-07-06, Last modification date: 2023-09-13) |
Primary citation | Beltrami, A.,Chaikuad, A.,Daga, N.,Elkins, J.M.,Mahajan, P.,Savitsky, P.,Vollmar, M.,Krojer, T.,Muniz, J.R.C.,Fedorov, O.,Allerston, C.K.,Yue, W.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Bullock, A. Crystal structure of the human LIMK1 kinase domain in complex with staurosporine To be Published, |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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