3S95
Crystal structure of the human LIMK1 kinase domain in complex with staurosporine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LIM domain kinase 1 | polymer | 310 | 35994.8 | 2 | UniProt (P53667) Pfam (PF07714) | Homo sapiens (human) | LIMK-1 |
| 2 | C, P (A, B) | STAUROSPORINE | non-polymer | 466.5 | 2 | Chemie (STU) | |||
| 3 | D, Q (A, B) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 4 | E, F, G, H, I... (A, B) | GLYCEROL | non-polymer | 92.1 | 11 | Chemie (GOL) | |||
| 5 | N, U (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | O, V (A, B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 2 | Chemie (TRS) | |||
| 7 | T (B) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) | |||
| 8 | W, X (A, B) | water | water | 18.0 | 582 | Chemie (HOH) |
Sequence modifications
A, B: 330 - 637 (UniProt: P53667)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71989.5 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2425.4 | |
| All* | Total formula weight | 74415.0 |
