6FDY

Unc-51-Like Kinase 3 (ULK3) In Complex With Bosutinib

Summary for 6FDY

• Entry DOI: 10.2210/pdb6fdy/pdb
• Descriptor: Serine/threonine-protein kinase ULK3, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile (3 entities in total)
• Functional Keywords: kinase inhibitor dfg-in, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 33000.87

Authors

Mathea, S.,Salah, E.,Moroglu, M.,Scorah, A.,Krojer, T.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Knapp, S. (deposition date: 2017-12-27, release date: 2018-08-01, Last modification date: 2024-01-17)

• Primary citation: Mathea, S.,Salah, E.,Moroglu, M.,Scorah, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Knapp, S.; Unc-51-Like Kinase 3 (ULK3) In Complex With Bosutinib; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.7 Å)