3SN5
Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one
Summary for 3SN5
Entry DOI | 10.2210/pdb3sn5/pdb |
Descriptor | Cholesterol 7-alpha-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE, (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ... (5 entities in total) |
Functional Keywords | cytochrome p450, cholesterol 7-alpha hydroxylase, cyp7a1, cholest-4-en-3-one, bile acid biosynthesis, structural genomics, structural genomics consortium, sgc, oxidoreductase |
Biological source | Homo sapiens (human) |
Cellular location | Endoplasmic reticulum membrane; Peripheral membrane protein: P22680 |
Total number of polymer chains | 2 |
Total formula weight | 114965.92 |
Authors | Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2011-06-28, release date: 2011-07-13, Last modification date: 2023-09-13) |
Primary citation | Strushkevich, N.,Tempel, W.,MacKenzie, F.,Wernimont, A.K.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Park, H. Crystal structure of human CYP7A1 in complex with cholest-4-en-3-one To be Published, |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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