8SGW
 
 | | Pendrin in complex with chloride | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHLORIDE ION, CHOLESTEROL, ... | | 著者 | Wang, L, Hoang, A, Zhou, M. | | 登録日 | 2023-04-13 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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8SHC
 | | Pendrin in complex with Niflumic acid | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, ... | | 著者 | Wang, L, Hoang, A, Zhou, M. | | 登録日 | 2023-04-13 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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8SIE
 | | Pendrin in complex with bicarbonate | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, BICARBONATE ION, CHOLESTEROL, ... | | 著者 | Wang, L, Hoang, A, Zhou, M. | | 登録日 | 2023-04-16 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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4YOQ
 | | Crystal Structure of MutY bound to its anti-substrate | | 分子名称: | A/G-specific adenine glycosylase, DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3'), DNA (5'-D(*T*GP*TP*CP*CP*AP*CP*GP*TP*CP*T)-3'), ... | | 著者 | Wang, L, Lee, S, Verdine, G.L. | | 登録日 | 2015-03-11 | | 公開日 | 2015-05-27 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
J.Biol.Chem., 290, 2015
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3TK9
 | | Crystal structure of human granzyme H | | 分子名称: | Granzyme H, SULFATE ION | | 著者 | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | | 登録日 | 2011-08-25 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
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3TJV
 | | Crystal structure of human granzyme H with a peptidyl substrate | | 分子名称: | Granzyme H, PTSYAGDDSG, SULFATE ION | | 著者 | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | | 登録日 | 2011-08-25 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
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3TJU
 | | Crystal structure of human granzyme H with an inhibitor | | 分子名称: | Ac-PTSY-CMK inhibitor, Granzyme H, SULFATE ION | | 著者 | Wang, L, Zhang, K, Wu, L, Tong, L, Sun, F, Fan, Z. | | 登録日 | 2011-08-25 | | 公開日 | 2011-12-28 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural insights into the substrate specificity of human granzyme H: the functional roles of a novel RKR motif
J.Immunol., 188, 2012
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1BLR
 | | NMR SOLUTION STRUCTURE OF HUMAN CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II, 22 STRUCTURES | | 分子名称: | CELLULAR RETINOIC ACID BINDING PROTEIN-TYPE II | | 著者 | Wang, L, Li, Y, Abilddard, F, Yan, H, Markely, J. | | 登録日 | 1998-07-20 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of type II human cellular retinoic acid binding protein: implications for ligand binding.
Biochemistry, 37, 1998
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8WWC
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6BFN
 | | Crystal structure of human IRAK1 | | 分子名称: | Interleukin-1 receptor-associated kinase 1, N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide | | 著者 | Wang, L, Qiao, Q, Wu, H. | | 登録日 | 2017-10-26 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | | 主引用文献 | Crystal structure of human IRAK1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6D26
 | | Crystal structure of the prostaglandin D2 receptor CRTH2 with fevipiprant | | 分子名称: | OLEIC ACID, Prostaglandin D2 receptor 2, Endolysin chimera, ... | | 著者 | Wang, L, Yao, D, Deepak, K, Liu, H, Gong, W, Fan, H, Wei, Z, Zhang, C. | | 登録日 | 2018-04-13 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.798 Å) | | 主引用文献 | Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition.
Mol. Cell, 72, 2018
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6D27
 | | Crystal structure of the prostaglandin D2 receptor CRTH2 with CAY10471 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, OLEIC ACID, ... | | 著者 | Wang, L, Yao, D, Deepak, K, Liu, H, Gong, W, Fan, H, Wei, Z, Zhang, C. | | 登録日 | 2018-04-13 | | 公開日 | 2018-10-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.738 Å) | | 主引用文献 | Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition.
Mol. Cell, 72, 2018
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6EGA
 | | IRAK4 in complex with a type II inhibitor | | 分子名称: | 3-{2-[(cyclopropanecarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}-N-{4-[(piperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide, COBALT (II) ION, Interleukin-1 receptor-associated kinase 4, ... | | 著者 | Wang, L, Wu, H. | | 登録日 | 2018-08-19 | | 公開日 | 2019-02-20 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.512 Å) | | 主引用文献 | Conformational flexibility and inhibitor binding to unphosphorylated interleukin-1 receptor-associated kinase 4 (IRAK4).
J.Biol.Chem., 294, 2019
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7Y0O
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7Y0N
 | | SARS-CoV-2 WT Spike in complex with R15 Fab and P14 Nanobody | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of R15-F7, ... | | 著者 | Wang, L. | | 登録日 | 2022-06-05 | | 公開日 | 2023-09-13 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | SARS-CoV-2 WT Spike in complex with R15 Fab and P14 Nanobody
To Be Published
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7VHM
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7YR4
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5YR2
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7E1A
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7ZYU
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7DV5
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2LKU
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2LKT
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8UUK
 | | Pendrin in apo | | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, Lauryl Maltose Neopentyl Glycol, ... | | 著者 | Wang, L, Hoang, A, Zhou, M. | | 登録日 | 2023-11-01 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Mechanism of anion exchange and small-molecule inhibition of pendrin.
Nat Commun, 15, 2024
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7UPT
 | | Human mitochondrial AAA protein ATAD1 (with a catalytic dead mutation) in complex with a peptide substrate (open conformation) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Wang, L, Toutkoushian, H, Belyy, V, Kokontis, C, Walter, P. | | 登録日 | 2022-04-16 | | 公開日 | 2022-06-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Conserved structural elements specialize ATAD1 as a membrane protein extraction machine.
Elife, 11, 2022
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