8SHC

Pendrin in complex with Niflumic acid

Summary for 8SHC

• Entry DOI: 10.2210/pdb8shc/pdb
• EMDB information: 40483
• Descriptor: Pendrin, CHLORIDE ION, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, ... (6 entities in total)
• Functional Keywords: chloride transport, iodide transport, bicarbonate transport, transport protein
• Biological source: Sus scrofa (pig)
• Total number of polymer chains: 2
• Total formula weight: 195768.29

Authors

Wang, L.,Hoang, A.,Zhou, M. (deposition date: 2023-04-13, release date: 2024-02-07, Last modification date: 2024-02-28)

• Primary citation: Wang, L.,Hoang, A.,Gil-Iturbe, E.,Laganowsky, A.,Quick, M.,Zhou, M.; Mechanism of anion exchange and small-molecule inhibition of pendrin.; Nat Commun, 15:346-346, 2024; PubMed: 38184688; DOI: 10.1038/s41467-023-44612-1

Experimental method

ELECTRON MICROSCOPY (3 Å)