2ZKE
| Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA | 分子名称: | DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3'), DNA (5'-D(*DGP*DCP*DAP*DAP*DTP*DCP*(5CM)P*DGP*DGP*DTP*DAP*DG)-3'), E3 ubiquitin-protein ligase UHRF1 | 著者 | Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. | 登録日 | 2008-03-19 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
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2RR9
| The solution structure of the K63-Ub2:tUIMs complex | 分子名称: | Putative uncharacterized protein UIMC1, ubiquitin | 著者 | Sekiyama, N, Jee, J, Isogai, S, Akagi, K, Huang, T, Ariyoshi, M, Tochio, H, Shirakawa, M. | 登録日 | 2010-06-16 | 公開日 | 2011-07-06 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | The solution structure of the K63-Ub2:tUIMs complex To be Published
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2ZKG
| Crystal structure of unliganded SRA domain of mouse Np95 | 分子名称: | 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase UHRF1 | 著者 | Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. | 登録日 | 2008-03-19 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
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2RRU
| Solution structure of the UBA omain of p62 and its interaction with ubiquitin | 分子名称: | Sequestosome-1 | 著者 | Isogai, S, Morimoto, D, Arita, K, Unzai, S, Tenno, T, Hasegawa, J, Sou, Y, Komatsu, M, Tanaka, K, Shirakawa, M, Tochio, H. | 登録日 | 2011-06-09 | 公開日 | 2011-06-29 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Crystal structure of the UBA omain of p62 and its interaction with ubiquitin To be Published
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2ZKF
| Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA | 分子名称: | DNA (5'-D(*DCP*DTP*DAP*DTP*DCP*(5CM)P*DGP*DGP*DTP*DGP*DA)-3'), DNA (5'-D(P*DCP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DAP*DGP*DA)-3'), E3 ubiquitin-protein ligase UHRF1 | 著者 | Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. | 登録日 | 2008-03-19 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
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2ZKD
| Crystal structure of the SRA domain of mouse Np95 in complex with hemi-methylated CpG DNA | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(*DCP*DTP*DAP*DCP*DCP*DGP*DGP*DAP*DTP*DTP*DGP*DC)-3'), ... | 著者 | Arita, K, Ariyoshi, M, Tochio, H, Nakamura, Y, Shirakawa, M. | 登録日 | 2008-03-19 | 公開日 | 2008-09-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism Nature, 455, 2008
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3A4S
| The crystal structure of the SLD2:Ubc9 complex | 分子名称: | NFATC2-interacting protein, SUMO-conjugating enzyme UBC9 | 著者 | Sekiyama, N, Arita, K, Ikeda, Y, Ariyoshi, M, Tochio, H, Saitoh, H, Shirakawa, M. | 登録日 | 2009-07-14 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for regulation of poly-SUMO chain by a SUMO-like domain of Nip45 Proteins, 78, 2009
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3W6I
| Crystal structure of 19F probe-labeled hCAI | 分子名称: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, Carbonic anhydrase 1, ZINC ION | 著者 | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | 登録日 | 2013-02-14 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.693 Å) | 主引用文献 | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR To be published
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3W6H
| Crystal structure of 19F probe-labeled hCAI in complex with acetazolamide | 分子名称: | 1-(2-ethoxyethoxy)-3,5-bis(trifluoromethyl)benzene, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase 1, ... | 著者 | Takaoka, Y, Kioi, Y, Morito, A, Otani, J, Arita, K, Ashihara, E, Ariyoshi, M, Tochio, H, Shirakawa, M, Hamachi, I. | 登録日 | 2013-02-14 | 公開日 | 2013-03-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.964 Å) | 主引用文献 | Quantitative Comparison of Protein Dynamics in Live Cells and In Vitro by In-Cell 19F-NMR To be published
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3WO2
| Crystal structure of human interleukin-18 | 分子名称: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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3WO4
| Crystal structure of the IL-18 signaling ternary complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H. | 登録日 | 2013-12-19 | 公開日 | 2014-12-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | The structural basis for receptor recognition of human interleukin-18 Nat Commun, 5, 2014
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1J0S
| Solution structure of the human interleukin-18 | 分子名称: | Interleukin-18 | 著者 | Kato, Z, Jee, J, Shikano, H, Mishima, M, Ohki, I, Yoneda, T, Hara, T, Torigoe, K, Kondo, N, Shirakawa, M. | 登録日 | 2002-11-21 | 公開日 | 2003-11-11 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | The structure and binding mode of interleukin-18 Nat.Struct.Biol., 10, 2003
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1GEA
| RECEPTOR-BOUND CONFORMATION OF PACAP21 | 分子名称: | PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE | 著者 | Inooka, H, Ohtaki, T, Kitahara, O, Ikegami, T, Endo, S, Kitada, C, Ogi, K, Onda, H, Fujino, M, Shirakawa, M. | 登録日 | 2000-10-20 | 公開日 | 2001-04-20 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Conformation of a peptide ligand bound to its G-protein coupled receptor. Nat.Struct.Biol., 8, 2001
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2RRI
| NMR structure of vasoactive intestinal peptide in DPC Micelle | 分子名称: | Vasoactive intestinal peptide | 著者 | Umetsu, Y, Tenno, T, Goda, N, Shirakawa, M, Ikegami, T, Hiroaki, H. | 登録日 | 2010-12-21 | 公開日 | 2011-04-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments Biochim.Biophys.Acta, 1814, 2011
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2RQQ
| Structure of C-terminal region of Cdt1 | 分子名称: | DNA replication factor Cdt1 | 著者 | Jee, J.G, Mizuno, T, Kamada, K, Tochio, H, Hiroaki, H, Hanaoka, F, Shirakawa, M. | 登録日 | 2009-10-14 | 公開日 | 2010-03-23 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and mutagenesis studies of the C-terminal region of licensing factor Cdt1 enable the identification of key residues for binding to replicative helicase Mcm proteins J.Biol.Chem., 285, 2010
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2RPA
| The solution structure of N-terminal domain of microtubule severing enzyme | 分子名称: | Katanin p60 ATPase-containing subunit A1 | 著者 | Iwaya, N, Kuwahara, Y, Unzai, S, Nagata, T, Tomii, K, Goda, N, Tochio, H, Shirakawa, M, Hiroaki, H. | 登録日 | 2008-05-13 | 公開日 | 2009-05-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A common substrate recognition mode conserved between katanin P60 and VPS4 governs microtubule severing and membrane skeleton reorganization J.Biol.Chem., 285, 2010
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2Z5V
| Solution structure of the TIR domain of human MyD88 | 分子名称: | Myeloid differentiation primary response protein MyD88 | 著者 | Ohnishi, H, Tochio, H, Hiroaki, H, Kondo, N, Kato, Z, Shirakawa, M. | 登録日 | 2007-07-19 | 公開日 | 2008-08-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc.Natl.Acad.Sci.USA, 2009
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3WA0
| Crystal structure of merlin complexed with DCAF1/VprBP | 分子名称: | Merlin, Protein VPRBP | 著者 | Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T. | 登録日 | 2013-04-20 | 公開日 | 2014-05-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function. Genes Cells, 19, 2014
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1FR0
| SOLUTION STRUCTURE OF THE HISTIDINE-CONTAINING PHOSPHOTRANSFER DOMAIN OF ANAEROBIC SENSOR KINASE ARCB FROM ESCHERICHIA COLI. | 分子名称: | ARCB | 著者 | Ikegami, T, Okada, T, Ohki, I, Hirayama, J, Mizuno, T, Shirakawa, M. | 登録日 | 2000-09-07 | 公開日 | 2001-03-14 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure and dynamic character of the histidine-containing phosphotransfer domain of anaerobic sensor kinase ArcB from Escherichia coli. Biochemistry, 40, 2001
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8IM5
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5BCA
| BETA-AMYLASE FROM BACILLUS CEREUS VAR. MYCOIDES | 分子名称: | CALCIUM ION, PROTEIN (1,4-ALPHA-D-GLUCAN MALTOHYDROLASE.) | 著者 | Oyama, T, Kusunoki, M, Kishimoto, Y, Takasaki, Y, Nitta, Y. | 登録日 | 1999-03-12 | 公開日 | 2000-03-15 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structure of beta-amylase from Bacillus cereus var. mycoides at 2.2 A resolution. J.Biochem.(Tokyo), 125, 1999
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5WVO
| Crystal structure of DNMT1 RFTS domain in complex with K18/K23 mono-ubiquitylated histone H3 | 分子名称: | DNA (cytosine-5)-methyltransferase 1, Histone H3.1, Ubiquitin, ... | 著者 | Ishiyama, S, Nishiyama, A, Nakanishi, M, Arita, K. | 登録日 | 2016-12-28 | 公開日 | 2017-11-15 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance Mol. Cell, 68, 2017
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5B3G
| The crystal structure of the heterodimer of SHORT-ROOT and SCARECROW GRAS domains | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Hirano, Y, Nakagawa, M, Hakoshima, T. | 登録日 | 2016-02-29 | 公開日 | 2017-03-01 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD Nat Plants, 3, 2017
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5B3H
| The crystal structure of the JACKDAW/IDD10 bound to the heterodimeric SHR-SCR complex | 分子名称: | Protein SCARECROW, Protein SHORT-ROOT, ZINC ION, ... | 著者 | Hirano, Y, Suyama, T, Nakagawa, M, Hakoshima, T. | 登録日 | 2016-02-29 | 公開日 | 2017-03-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of the SHR-SCR heterodimer bound to the BIRD/IDD transcriptional factor JKD Nat Plants, 3, 2017
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6M5W
| Co-crystal structure of human serine hydroxymethyltransferase 1 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Ota, T, Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K, Sando, S. | 登録日 | 2020-03-11 | 公開日 | 2021-01-20 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate. Iscience, 24, 2021
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