7EET
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![BU of 7eet by Molmil](/molmil-images/mine/7eet) | Mannanase KMAN from Klebsiella oxytoca KUB-CW2-3 | 分子名称: | Mannanase KMAN, SULFATE ION | 著者 | Pongsapipatana, N, Charoenwattanasatien, R, Pramanpol, N, Nitisinprasert, S, Keawsompong, S. | 登録日 | 2021-03-19 | 公開日 | 2021-11-10 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Crystallization, structural characterization and kinetic analysis of a GH26 beta-mannanase from Klebsiella oxytoca KUB-CW2-3. Acta Crystallogr D Struct Biol, 77, 2021
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4AOF
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![BU of 4aof by Molmil](/molmil-images/mine/4aof) | Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma | 分子名称: | N-[6-(5-methylsulfonylpyridin-3-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]ethanamide, PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT GAMMA ISOFORM | 著者 | Bergamini, G, Bell, K, Shimamura, S, Werner, T, Cansfield, A, Muller, K, Perrin, J, Rau, C, Ellard, K, Hopf, C, Doce, C, Leggate, D, Mangano, R, Mathieson, T, OMahony, A, Plavec, I, Rharbaoui, F, Reinhard, F, Savitski, M.M, Ramsden, N, Hirsch, E, Drewes, G, Rausch, O, Bantscheff, M, Neubauer, G. | 登録日 | 2012-03-26 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | A Selective Inhibitor Reveals Pi3Kgamma Dependence of T(H)17 Cell Differentiation. Nat.Chem.Biol., 8, 2012
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7CGV
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![BU of 7cgv by Molmil](/molmil-images/mine/7cgv) | Full consensus L-threonine 3-dehydrogenase, FcTDH-IIYM (NAD+ bound form) | 分子名称: | Artificial L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Motoyama, T, Hiramatsu, N, Asano, Y, Nakano, S, Ito, S. | 登録日 | 2020-07-02 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.38 Å) | 主引用文献 | Protein Sequence Selection Method That Enables Full Consensus Design of Artificial l-Threonine 3-Dehydrogenases with Unique Enzymatic Properties. Biochemistry, 59, 2020
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2JZW
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![BU of 2jzw by Molmil](/molmil-images/mine/2jzw) | How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription | 分子名称: | DNA (5'-D(*DGP*DTP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DCP*DGP*DGP*DGP*DC)-3'), HIV-1 nucleocapsid protein NCp7(12-55), ZINC ION | 著者 | Bourbigot, S, Ramalanjaona, N, Salgado, G.F.J, Mely, Y, Roques, B.P, Bouaziz, S, Morellet, N. | 登録日 | 2008-01-21 | 公開日 | 2009-01-13 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription. J.Mol.Biol., 383, 2008
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1N3R
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![BU of 1n3r by Molmil](/molmil-images/mine/1n3r) | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-10-29 | 公開日 | 2003-10-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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1N3S
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![BU of 1n3s by Molmil](/molmil-images/mine/1n3s) | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-10-29 | 公開日 | 2004-03-02 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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1N3T
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![BU of 1n3t by Molmil](/molmil-images/mine/1n3t) | Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I | 分子名称: | GTP cyclohydrolase I, GUANOSINE-5'-TRIPHOSPHATE | 著者 | Rebelo, J, Auerbach, G, Bader, G, Bracher, A, Nar, H, Hoesl, C, Schramek, N, Kaiser, J, Bacher, A, Huber, R, Fischer, M. | 登録日 | 2002-10-29 | 公開日 | 2003-10-14 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Biosynthesis of Pteridines. Reaction Mechanism of GTP Cyclohydrolase I J.MOL.BIOL., 326, 2003
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2DH1
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![BU of 2dh1 by Molmil](/molmil-images/mine/2dh1) | Crystal structure of peanut lectin lactose-azobenzene-4,4'-dicarboxylic acid-lactose complex | 分子名称: | Galactose-binding lectin | 著者 | Natchiar, S.K, Srinivas, O, Nivedita, M, Sagarika, D, Jayaraman, N, Surolia, A, Vijayan, M. | 登録日 | 2006-03-17 | 公開日 | 2006-08-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (7.65 Å) | 主引用文献 | Multivalency in lectins - A crystallographic, modelling and light-scattering study involving peanut lectin and a bivalent ligand Curr.Sci., 90, 2006
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2DVB
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![BU of 2dvb by Molmil](/molmil-images/mine/2dvb) | Crystal structure of peanut lectin GAl-beta-1,6-GalNAc complex | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Natchiar, S.K, Srinivas, O, Mitra, N, Surolia, A, Jayaraman, N, Vijayan, M. | 登録日 | 2006-07-30 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2DVF
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![BU of 2dvf by Molmil](/molmil-images/mine/2dvf) | Crystals of peanut lectin grown in the presence of GAL-ALPHA-1,3-GAL-BETA-1,4-GAL | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Natchiar, S.K, Srinivas, O, Mitra, N, Surolia, A, Jayaraman, N, Vijayan, M. | 登録日 | 2006-07-31 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | 主引用文献 | Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2DVD
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![BU of 2dvd by Molmil](/molmil-images/mine/2dvd) | Crystal structure of peanut lectin GAL-ALPHA-1,3-GAL complex | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Natchiar, S.K, Srinivas, O, Mitra, N, Surolia, A, Jayaraman, N, Vijayan, M. | 登録日 | 2006-07-31 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2DV9
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![BU of 2dv9 by Molmil](/molmil-images/mine/2dv9) | Crystal structure of peanut lectin GAL-BETA-1,3-GAL complex | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Natchiar, S.K, Srinivas, O, Mitra, N, Surolia, A, Jayaraman, N, Vijayan, M. | 登録日 | 2006-07-30 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2DVA
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![BU of 2dva by Molmil](/molmil-images/mine/2dva) | Crystal structure of peanut lectin GAL-BETA-1,3-GALNAC-ALPHA-O-ME (Methyl-T-antigen) complex | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Natchiar, S.K, Srinivas, O, Mitra, N, Surolia, A, Jayaraman, N, Vijayan, M. | 登録日 | 2006-07-30 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2DVG
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![BU of 2dvg by Molmil](/molmil-images/mine/2dvg) | Crystal structure of peanut lectin GAL-ALPHA-1,6-GLC complex | 分子名称: | CALCIUM ION, Galactose-binding lectin, MANGANESE (II) ION, ... | 著者 | Natchiar, S.K, Srinivas, O, Mitra, N, Surolia, A, Jayaraman, N, Vijayan, M. | 登録日 | 2006-07-31 | 公開日 | 2006-11-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.78 Å) | 主引用文献 | Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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2MXX
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![BU of 2mxx by Molmil](/molmil-images/mine/2mxx) | |
1YQN
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![BU of 1yqn by Molmil](/molmil-images/mine/1yqn) | E. coli ispF double mutant | 分子名称: | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-DIPHOSPHATE, GERANYL DIPHOSPHATE, ... | 著者 | Sgraja, T, Kemp, L.E, Ramsden, N, Hunter, W.N. | 登録日 | 2005-02-02 | 公開日 | 2005-07-12 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | A double mutation of Escherichia coli2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase disrupts six hydrogen bonds with, yet fails to prevent binding of, an isoprenoid diphosphate. Acta Crystallogr.,Sect.F, 61, 2005
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1HVS
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![BU of 1hvs by Molmil](/molmil-images/mine/1hvs) | STRUCTURAL BASIS OF DRUG RESISTANCE FOR THE V82A MUTANT OF HIV-1 PROTEASE: BACKBONE FLEXIBILITY AND SUBSITE REPACKING | 分子名称: | HIV-1 PROTEASE, N-{1-BENZYL-(2R,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | 著者 | Baldwin, E.T, Bhat, T.N, Liu, B, Pattabiraman, N, Erickson, J.W. | 登録日 | 1994-11-17 | 公開日 | 1995-02-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase. Nat.Struct.Biol., 2, 1995
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6RHK
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![BU of 6rhk by Molmil](/molmil-images/mine/6rhk) | The crystal structure of human carbonic anhydrase II in complex with 4-(3-benzylimidazolidine-1-carbonyl)benzenesulfonamide | 分子名称: | 4-[3-(phenylmethyl)imidazolidin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Ferraroni, M, Angeli, A, Supuran, C.T. | 登録日 | 2019-04-22 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. Bioorg.Chem., 91, 2019
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6RG4
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![BU of 6rg4 by Molmil](/molmil-images/mine/6rg4) | Crystal structure of human Carbonic anhydrase II in complex with (R)-4-(2-benzyl-4-methylpiperazin-1-yl)benzenesulfonamide | 分子名称: | 4-[(3~{S})-4-methyl-3-(phenylmethyl)piperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Ferraroni, M, Angeli, A, Supuran, C. | 登録日 | 2019-04-16 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. Bioorg.Chem., 91, 2019
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6RG3
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![BU of 6rg3 by Molmil](/molmil-images/mine/6rg3) | Crystal structure of human Carbonic anhydrase II in complex with (R)-4-(2-benzylpiperazin-1-yl)benzenesulfonamide | 分子名称: | 4-[(2~{R})-2-(phenylmethyl)piperazin-1-yl]carbonylbenzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Ferraroni, M, Angeli, A, Supuran, C. | 登録日 | 2019-04-16 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.32 Å) | 主引用文献 | Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. Bioorg.Chem., 91, 2019
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6RHJ
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![BU of 6rhj by Molmil](/molmil-images/mine/6rhj) | Crystal structure of human carbonic anhydrase isozyme II with 4-(4-benzyl-1,4-diazepane-1-carbonyl)benzenesulfonamide | 分子名称: | 4-[[4-(phenylmethyl)-1,4-diazepan-1-yl]carbonyl]benzenesulfonamide, Carbonic anhydrase 2, GLYCEROL, ... | 著者 | Ferraroni, M, Angeli, A, Supuran, C.T. | 登録日 | 2019-04-21 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Sulfonamides incorporating piperazine bioisosteres as potent human carbonic anhydrase I, II, IV and IX inhibitors. Bioorg.Chem., 91, 2019
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8RY2
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![BU of 8ry2 by Molmil](/molmil-images/mine/8ry2) | |
7REP
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![BU of 7rep by Molmil](/molmil-images/mine/7rep) | |
7REO
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![BU of 7reo by Molmil](/molmil-images/mine/7reo) | |
4Z89
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![BU of 4z89 by Molmil](/molmil-images/mine/4z89) | SH3-II of Drosophila Rim-binding protein bound to a Cacophony derived peptide | 分子名称: | CALCIUM ION, RIM-binding protein, isoform F, ... | 著者 | Driller, J.H, Holton, N, Siebert, M, Boehme, M.A, Wahl, M.C, Sigrist, S.J, Loll, B. | 登録日 | 2015-04-08 | 公開日 | 2015-08-05 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones. Elife, 4, 2015
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