2JZW
How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription
Summary for 2JZW
| Entry DOI | 10.2210/pdb2jzw/pdb |
| Descriptor | HIV-1 nucleocapsid protein NCp7(12-55), DNA (5'-D(*DGP*DTP*DCP*DCP*DCP*DTP*DGP*DTP*DTP*DCP*DGP*DGP*DGP*DC)-3'), ZINC ION (3 entities in total) |
| Functional Keywords | human immunodeficiency virus type 1 (hiv-1), nuclear magnetic resonance (nmr), nucleocapsid protein (ncp7), primer binding site (pbs), exchange, viral protein-dna complex, viral protein/dna |
| Total number of polymer chains | 2 |
| Total formula weight | 9417.39 |
| Authors | Bourbigot, S.,Ramalanjaona, N.,Salgado, G.F.J.,Mely, Y.,Roques, B.P.,Bouaziz, S.,Morellet, N. (deposition date: 2008-01-21, release date: 2009-01-13, Last modification date: 2022-03-16) |
| Primary citation | Bourbigot, S.,Ramalanjaona, N.,Boudier, C.,Salgado, G.F.,Roques, B.P.,Mely, Y.,Bouaziz, S.,Morellet, N. How the HIV-1 nucleocapsid protein binds and destabilises the (-)primer binding site during reverse transcription. J.Mol.Biol., 383:1112-1128, 2008 Cited by PubMed: 18773912DOI: 10.1016/j.jmb.2008.08.046 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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