6TUH
 
 | | The PH domain of Bruton's tyrosine kinase mutant R28C | | 分子名称: | 4,5,6,7-tetrahydro-1-benzofuran-3-carboxylic acid, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... | | 著者 | Brear, P, Wagstaff, J, Hyvonen, M. | | 登録日 | 2020-01-07 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C
To Be Published
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6TVN
 | | Crystal Structure of 5-bromoindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase | | 分子名称: | 5-bromanyl-1,3-dihydroindol-2-one, MAGNESIUM ION, Tyrosine-protein kinase BTK, ... | | 著者 | Brear, P, Wagstaff, J, Hyvonen, M. | | 登録日 | 2020-01-10 | | 公開日 | 2020-11-25 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Crystal Structure of 1-methylindoline-2,3-dione covalently bound to the PH domain of Bruton's tyrosine kinase mutant R28C
To Be Published
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7AFZ
 | | L1 metallo-b-lactamase with compound EBL-1306 | | 分子名称: | 3-[3-chloranyl-4-(methylsulfonylmethyl)phenyl]-7-propan-2-yl-1~{H}-indole-2-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... | | 著者 | Hinchliffe, P, Spencer, J, Brem, J. | | 登録日 | 2020-09-21 | | 公開日 | 2021-10-06 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Imitation of beta-lactam binding enables broad-spectrum metallo-beta-lactamase inhibitors.
Nat.Chem., 14, 2022
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4Z22
 | | structure of plasmepsin II from Plasmodium Falciparum complexed with inhibitor DR718A | | 分子名称: | 2-amino-7-phenyl-3-{[(2R,5S)-5-phenyltetrahydrofuran-2-yl]methyl}quinazolin-4(3H)-one, Plasmepsin-2 | | 著者 | Recacha, R, Leitans, J, Tars, K, Jaudzems, K. | | 登録日 | 2015-03-28 | | 公開日 | 2016-01-13 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV.
J.Med.Chem., 59, 2016
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7ZNX
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7AYJ
 | | Metallo beta-lactamse Vim-1 with a sulfamoyl inhibitor. | | 分子名称: | 3-(4-fluorophenyl)-1-sulfamoyl-pyrrole-2-carboxylic acid, Beta-lactamase VIM-1, ZINC ION | | 著者 | Farley, A.J.M, Ermolovich, I, Calvopina, K, Rabe, P, Brem, J, Schofield, C.J. | | 登録日 | 2020-11-12 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | | 主引用文献 | Structural Basis of Metallo-beta-lactamase Inhibition by N -Sulfamoylpyrrole-2-carboxylates.
Acs Infect Dis., 7, 2021
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3G8A
 | | T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoHcy in space group P61 | | 分子名称: | Ribosomal RNA small subunit methyltransferase G, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | | 登録日 | 2009-02-11 | | 公開日 | 2009-06-30 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Rna, 15, 2009
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3G89
 | | T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet and AMP in space group P61 | | 分子名称: | ADENOSINE MONOPHOSPHATE, Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE | | 著者 | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | | 登録日 | 2009-02-11 | | 公開日 | 2009-06-30 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Rna, 15, 2009
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3G8B
 | | T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet in space group I222 | | 分子名称: | Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE, SULFATE ION | | 著者 | Demirci, H, Gregory, S.T, Belardinelli, R, Gualerzi, C, Dahlberg, A.E, Jogl, G. | | 登録日 | 2009-02-11 | | 公開日 | 2009-06-30 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Rna, 15, 2009
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3G88
 | | T. thermophilus 16S rRNA G527 methyltransferase in complex with AdoMet in space group P61 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Ribosomal RNA small subunit methyltransferase G, S-ADENOSYLMETHIONINE | | 著者 | Demirci, H, Belardinelli, R, Gregory, S.T, Gualerzi, C, Dahlberg, A.E, Jogl, G. | | 登録日 | 2009-02-11 | | 公開日 | 2009-06-30 | | 最終更新日 | 2019-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structural and functional studies of the Thermus thermophilus 16S rRNA methyltransferase RsmG
Rna, 15, 2009
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7MJR
 | | Vip4Da2 toxin structure | | 分子名称: | CALCIUM ION, SULFATE ION, Vip4Da1 protein | | 著者 | Rydel, T.J, Duda, D, Zheng, M, Henry, A. | | 登録日 | 2021-04-20 | | 公開日 | 2021-05-05 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | Structural and functional insights into the first Bacillus thuringiensis vegetative insecticidal protein of the Vpb4 fold, active against western corn rootworm.
Plos One, 16, 2021
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6FKG
 | | Crystal structure of the M.tuberculosis MbcT-MbcA toxin-antitoxin complex. | | 分子名称: | GLYCEROL, Rv1989c (MbcT), Rv1990c (MbcA) | | 著者 | Freire, D.M, Cianci, M, Pogenberg, V, Schneider, T.R, Wilmanns, M, Parret, A.H.A. | | 登録日 | 2018-01-24 | | 公開日 | 2019-02-27 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | An NAD+Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
Mol.Cell, 73, 2019
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5HJB
 | | AF9 YEATS in complex with histone H3 Crotonylation at K9 | | 分子名称: | Protein AF-9, peptide of Histone H3.1 | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-12 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
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5HJD
 | | AF9 YEATS in complex with histone H3 Crotonylation at K18 | | 分子名称: | COPPER (II) ION, Protein AF-9, SULFATE ION, ... | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.806 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
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5HJC
 | | BRD3 second bromodomain in complex with histone H3 acetylation at K18 | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ... | | 著者 | Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T. | | 登録日 | 2016-01-13 | | 公開日 | 2016-04-20 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
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5B76
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5B78
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5B75
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5B77
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5B79
 | | Crystal structure of DPF2 double PHD finger | | 分子名称: | ZINC ION, Zinc finger protein ubi-d4 | | 著者 | Li, H, Xiong, X. | | 登録日 | 2016-06-05 | | 公開日 | 2016-10-26 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | | 主引用文献 | Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2
Nat.Chem.Biol., 12, 2016
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7D4B
 | | Crystal structure of 4-1BB in complex with a VHH | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | | 著者 | Wang, C. | | 登録日 | 2020-09-23 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.14 Å) | | 主引用文献 | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.
J Immunother Cancer, 9, 2021
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7CZD
 | | Crystal structure of PD-L1 in complex with a VHH | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Programmed cell death 1 ligand 1, ... | | 著者 | Wang, C. | | 登録日 | 2020-09-08 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Generation of a safe and efficacious llama single-domain antibody fragment (vHH) targeting the membrane-proximal region of 4-1BB for engineering therapeutic bispecific antibodies for cancer.
J Immunother Cancer, 9, 2021
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5QUH
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5QUD
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5QUE
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