7AYJ

Metallo beta-lactamse Vim-1 with a sulfamoyl inhibitor.

Summary for 7AYJ

Entry DOI	10.2210/pdb7ayj/pdb
Descriptor	Beta-lactamase VIM-1, ZINC ION, 3-(4-fluorophenyl)-1-sulfamoyl-pyrrole-2-carboxylic acid, ... (4 entities in total)
Functional Keywords	vim1, metallo beta lactamse, inhibition, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	27345.84
Authors	Farley, A.J.M.,Ermolovich, I.,Calvopina, K.,Rabe, P.,Brem, J.,Schofield, C.J. (deposition date: 2020-11-12, release date: 2021-05-12, Last modification date: 2024-01-31)
Primary citation	Farley, A.J.M.,Ermolovich, Y.,Calvopina, K.,Rabe, P.,Panduwawala, T.,Brem, J.,Bjorkling, F.,Schofield, C.J. Structural Basis of Metallo-beta-lactamase Inhibition by N -Sulfamoylpyrrole-2-carboxylates. Acs Infect Dis., 7:1809-1817, 2021 Cited by PubMed: 34003651 DOI: 10.1021/acsinfecdis.1c00104 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.21 Å)

Structure validation