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6W9S
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BU of 6w9s by Molmil
Crystal structure of an OTU deubiquitinase from Escherichia albertii bound to ubiquitin
分子名称: FORMIC ACID, OTU domain-containing protein EschOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2020-08-12
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
6W9R
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BU of 6w9r by Molmil
Crystal structure of an OTU deubiquitinase from Wolbachia pipientis wMel bound to ubiquitin
分子名称: CITRATE ANION, OTU domain-containing protein wMelOTU, Ubiquitin
著者Schubert, A.F, Pruneda, J.N, Komander, D.
登録日2020-03-23
公開日2020-07-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Identification and characterization of diverse OTU deubiquitinases in bacteria.
Embo J., 39, 2020
7QO6
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BU of 7qo6 by Molmil
26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2022-07-20
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7QO3
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BU of 7qo3 by Molmil
Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid)
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit RPN1, 26S proteasome regulatory subunit RPN10, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-04-13
実験手法ELECTRON MICROSCOPY (6.1 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7QO5
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BU of 7qo5 by Molmil
26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state
分子名称: 26S proteasome complex subunit SEM1, 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, T.C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-03-16
最終更新日2023-03-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
7QO4
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BU of 7qo4 by Molmil
26S proteasome WT-Ubp6-UbVS complex in the si state (ATPases, Rpn1, Ubp6, and UbVS)
分子名称: 26S proteasome regulatory subunit RPN1, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
著者Hung, K.Y.S, Klumpe, S, Eisele, M.R, Elsasser, S, Geng, T.T, Cheng, C, Joshi, T, Rudack, T, Sakata, E, Finley, D.
登録日2021-12-23
公開日2022-06-01
実験手法ELECTRON MICROSCOPY (7 Å)
主引用文献Allosteric control of Ubp6 and the proteasome via a bidirectional switch.
Nat Commun, 13, 2022
5JP3
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BU of 5jp3 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to ubiquitin
分子名称: Polyubiquitin-B, Xanthomonas outer protein D
著者Pruneda, J.N, Komander, D.
登録日2016-05-03
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5JP1
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BU of 5jp1 by Molmil
Structure of Xanthomonas campestris effector protein XopD bound to tomato SUMO
分子名称: (4S,5S)-1,2-DITHIANE-4,5-DIOL, MALONATE ION, Small ubiquitin-related modifier, ...
著者Pruneda, J.N, Komander, D.
登録日2016-05-03
公開日2016-07-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5CHV
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BU of 5chv by Molmil
Crystal structure of USP18-ISG15 complex
分子名称: CHLORIDE ION, SULFATE ION, Ubiquitin-like protein ISG15, ...
著者Fritz, G, Basters, A.
登録日2015-07-10
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.005 Å)
主引用文献Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
5E6J
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BU of 5e6j by Molmil
Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe
分子名称: ACETATE ION, NICKEL (II) ION, Polyubiquitin-B, ...
著者Lima, C.D, Bekes, M.
登録日2015-10-09
公開日2016-05-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.
Mol. Cell, 62, 2016
5CHT
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BU of 5cht by Molmil
Crystal structure of USP18
分子名称: Ubl carboxyl-terminal hydrolase 18, ZINC ION
著者Fritz, G, Basters, A.
登録日2015-07-10
公開日2016-06-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis of the specificity of USP18 toward ISG15.
Nat. Struct. Mol. Biol., 24, 2017
3ZRH
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BU of 3zrh by Molmil
Crystal structure of the Lys29, Lys33-linkage-specific TRABID OTU deubiquitinase domain reveals an Ankyrin-repeat ubiquitin binding domain (AnkUBD)
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, UBIQUITIN THIOESTERASE ZRANB1
著者Licchesi, J.D.F, Akutsu, M, Komander, D.
登録日2011-06-16
公開日2011-12-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献An Ankyrin-Repeat Ubiquitin-Binding Domain Determines Trabid'S Specificity for Atypical Ubiquitin Chains.
Nat.Struct.Mol.Biol., 19, 2011
7B5N
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BU of 7b5n by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-UBE2L3~Ub~ARIH1.
分子名称: 5-azanylpentan-2-one, Cullin-1, E3 ubiquitin-protein ligase ARIH1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-05
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5R
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BU of 7b5r by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27
分子名称: Cullin-1, Cyclin-A2, Cyclin-dependent kinase 2, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-07
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5S
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BU of 7b5s by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-ARIH1 Ariadne. Transition State 1
分子名称: Cullin-1, E3 ubiquitin-protein ligase ARIH1, E3 ubiquitin-protein ligase RBX1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-07
公開日2021-02-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5L
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BU of 7b5l by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1
分子名称: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-04
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
7B5M
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BU of 7b5m by Molmil
Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2
分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ...
著者Horn-Ghetko, D, Prabu, J.R, Schulman, B.A.
登録日2020-12-05
公開日2021-02-17
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (3.91 Å)
主引用文献Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly.
Nature, 590, 2021
5HAG
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BU of 5hag by Molmil
Structure of Chlamydia trachomatis effector protein ChlaDUB1
分子名称: Deubiquitinase and deneddylase Dub1, GLYCEROL
著者Pruneda, J.N, Komander, D.
登録日2015-12-30
公開日2016-07-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAF
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BU of 5haf by Molmil
Structure of Salmonella enterica effector protein SseL
分子名称: Deubiquitinase SseL, POTASSIUM ION
著者Pruneda, J.N, Komander, D.
登録日2015-12-30
公開日2016-07-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
5HAM
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BU of 5ham by Molmil
Structure of Rickettsia bellii effector protein RickCE
分子名称: RickCE
著者Pruneda, J.N, Komander, D.
登録日2015-12-30
公開日2016-07-27
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Mol.Cell, 63, 2016
2YLM
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BU of 2ylm by Molmil
Mechanism of USP7 (HAUSP) activation by its C-terminal ubiquitin-like domain (HUBL) and allosteric regulation by GMP-synthetase.
分子名称: CHLORIDE ION, UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7
著者Faesen, A.C, Perrakis, A, Sixma, T.K.
登録日2011-06-03
公開日2011-10-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of Usp7/Hausp Activation by its C- Terminal Ubiquitin-Like Domain and Allosteric Regulation by Gmp-Synthetase
Mol.Cell, 44, 2011
4PG9
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BU of 4pg9 by Molmil
MHC Class I in complex with Sendai virus nucleoprotein peptide FAPGNYPAL
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
登録日2014-05-01
公開日2015-01-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PGE
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BU of 4pge by Molmil
MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAW
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
登録日2014-05-01
公開日2015-01-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
4PGC
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BU of 4pgc by Molmil
MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGN(3,5-diiodotyrosine)PAL
分子名称: Beta-2-microglobulin, GLYCEROL, H-2 class I histocompatibility antigen, ...
著者Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
登録日2014-05-01
公開日2015-01-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015
2XR9
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BU of 2xr9 by Molmil
Crystal structure of Autotaxin (ENPP2)
分子名称: CALCIUM ION, ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE FAMILY MEMBER 2, IODIDE ION, ...
著者Kamtekar, S, Hausmann, J, Day, J.E, Christodoulou, E, Perrakis, A.
登録日2010-09-13
公開日2011-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural basis of substrate discrimination and integrin binding by autotaxin.
Nat. Struct. Mol. Biol., 18, 2011

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