7QO3

Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid)

Summary for 7QO3

Entry DOI	10.2210/pdb7qo3/pdb
EMDB information	14082
Descriptor	Proteasome subunit alpha type-1, Proteasome subunit beta type-3, Proteasome subunit beta type-4, ... (27 entities in total)
Functional Keywords	proteasome ubp6 ubiquitin allostery, motor protein
Biological source	Saccharomyces cerevisiae (baker's yeast) More
Total number of polymer chains	41
Total formula weight	1400614.52
Authors	Hung, K.Y.S.,Klumpe, S.,Eisele, M.R.,Elsasser, S.,Geng, T.T.,Cheng, T.C.,Joshi, T.,Rudack, T.,Sakata, E.,Finley, D. (deposition date: 2021-12-23, release date: 2022-04-13)
Primary citation	Hung, K.Y.S.,Klumpe, S.,Eisele, M.R.,Elsasser, S.,Tian, G.,Sun, S.,Moroco, J.A.,Cheng, T.C.,Joshi, T.,Seibel, T.,Van Dalen, D.,Feng, X.H.,Lu, Y.,Ovaa, H.,Engen, J.R.,Lee, B.H.,Rudack, T.,Sakata, E.,Finley, D. Allosteric control of Ubp6 and the proteasome via a bidirectional switch. Nat Commun, 13:838-838, 2022 Cited by PubMed: 35149681 DOI: 10.1038/s41467-022-28186-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (6.1 Å)

Structure validation