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7QO3

Structure of the 26S proteasome-Ubp6 complex in the si state (Core Particle and Lid)

Functional Information from GO Data
ChainGOidnamespacecontents
10000502cellular_componentproteasome complex
10004175molecular_functionendopeptidase activity
10004298molecular_functionthreonine-type endopeptidase activity
10005515molecular_functionprotein binding
10005634cellular_componentnucleus
10005737cellular_componentcytoplasm
10005829cellular_componentcytosol
10005839cellular_componentproteasome core complex
10006508biological_processproteolysis
10010499biological_processproteasomal ubiquitin-independent protein catabolic process
10019774cellular_componentproteasome core complex, beta-subunit complex
10034515cellular_componentproteasome storage granule
10043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
10051603biological_processproteolysis involved in protein catabolic process
20000502cellular_componentproteasome complex
20004175molecular_functionendopeptidase activity
20004298molecular_functionthreonine-type endopeptidase activity
20005515molecular_functionprotein binding
20005634cellular_componentnucleus
20005737cellular_componentcytoplasm
20005829cellular_componentcytosol
20005839cellular_componentproteasome core complex
20006508biological_processproteolysis
20010499biological_processproteasomal ubiquitin-independent protein catabolic process
20019774cellular_componentproteasome core complex, beta-subunit complex
20034515cellular_componentproteasome storage granule
20043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
20051603biological_processproteolysis involved in protein catabolic process
30000502cellular_componentproteasome complex
30005515molecular_functionprotein binding
30005634cellular_componentnucleus
30005737cellular_componentcytoplasm
30005829cellular_componentcytosol
30005839cellular_componentproteasome core complex
30010499biological_processproteasomal ubiquitin-independent protein catabolic process
30019774cellular_componentproteasome core complex, beta-subunit complex
30043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
30051603biological_processproteolysis involved in protein catabolic process
30061133molecular_functionendopeptidase activator activity
40000502cellular_componentproteasome complex
40005515molecular_functionprotein binding
40005634cellular_componentnucleus
40005737cellular_componentcytoplasm
40005789cellular_componentendoplasmic reticulum membrane
40005829cellular_componentcytosol
40005839cellular_componentproteasome core complex
40010498biological_processproteasomal protein catabolic process
40010499biological_processproteasomal ubiquitin-independent protein catabolic process
40019774cellular_componentproteasome core complex, beta-subunit complex
40043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
40051603biological_processproteolysis involved in protein catabolic process
40061133molecular_functionendopeptidase activator activity
50000502cellular_componentproteasome complex
50004175molecular_functionendopeptidase activity
50004298molecular_functionthreonine-type endopeptidase activity
50005515molecular_functionprotein binding
50005634cellular_componentnucleus
50005737cellular_componentcytoplasm
50005777cellular_componentperoxisome
50005829cellular_componentcytosol
50005839cellular_componentproteasome core complex
50006508biological_processproteolysis
50010499biological_processproteasomal ubiquitin-independent protein catabolic process
50019774cellular_componentproteasome core complex, beta-subunit complex
50043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
50051603biological_processproteolysis involved in protein catabolic process
50080129biological_processproteasome core complex assembly
60000502cellular_componentproteasome complex
60003674molecular_functionmolecular_function
60005515molecular_functionprotein binding
60005634cellular_componentnucleus
60005737cellular_componentcytoplasm
60005829cellular_componentcytosol
60005839cellular_componentproteasome core complex
60010499biological_processproteasomal ubiquitin-independent protein catabolic process
60019774cellular_componentproteasome core complex, beta-subunit complex
60043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
60051603biological_processproteolysis involved in protein catabolic process
70000502cellular_componentproteasome complex
70003674molecular_functionmolecular_function
70005515molecular_functionprotein binding
70005634cellular_componentnucleus
70005737cellular_componentcytoplasm
70005829cellular_componentcytosol
70005839cellular_componentproteasome core complex
70010499biological_processproteasomal ubiquitin-independent protein catabolic process
70019774cellular_componentproteasome core complex, beta-subunit complex
70034515cellular_componentproteasome storage granule
70043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
70043248biological_processproteasome assembly
70051603biological_processproteolysis involved in protein catabolic process
A0000502cellular_componentproteasome complex
A0003674molecular_functionmolecular_function
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005839cellular_componentproteasome core complex
A0006511biological_processubiquitin-dependent protein catabolic process
A0010499biological_processproteasomal ubiquitin-independent protein catabolic process
A0019773cellular_componentproteasome core complex, alpha-subunit complex
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0051603biological_processproteolysis involved in protein catabolic process
B0000502cellular_componentproteasome complex
B0003674molecular_functionmolecular_function
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005839cellular_componentproteasome core complex
B0006511biological_processubiquitin-dependent protein catabolic process
B0010499biological_processproteasomal ubiquitin-independent protein catabolic process
B0019773cellular_componentproteasome core complex, alpha-subunit complex
B0034515cellular_componentproteasome storage granule
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0051603biological_processproteolysis involved in protein catabolic process
C0000502cellular_componentproteasome complex
C0003674molecular_functionmolecular_function
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005839cellular_componentproteasome core complex
C0006511biological_processubiquitin-dependent protein catabolic process
C0010499biological_processproteasomal ubiquitin-independent protein catabolic process
C0019773cellular_componentproteasome core complex, alpha-subunit complex
C0034515cellular_componentproteasome storage granule
C0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
C0051603biological_processproteolysis involved in protein catabolic process
C0080129biological_processproteasome core complex assembly
D0000502cellular_componentproteasome complex
D0003674molecular_functionmolecular_function
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005839cellular_componentproteasome core complex
D0006511biological_processubiquitin-dependent protein catabolic process
D0010499biological_processproteasomal ubiquitin-independent protein catabolic process
D0019773cellular_componentproteasome core complex, alpha-subunit complex
D0034515cellular_componentproteasome storage granule
D0042175cellular_componentnuclear outer membrane-endoplasmic reticulum membrane network
D0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
D0051603biological_processproteolysis involved in protein catabolic process
E0000502cellular_componentproteasome complex
E0003674molecular_functionmolecular_function
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005839cellular_componentproteasome core complex
E0006511biological_processubiquitin-dependent protein catabolic process
E0010499biological_processproteasomal ubiquitin-independent protein catabolic process
E0019773cellular_componentproteasome core complex, alpha-subunit complex
E0034515cellular_componentproteasome storage granule
E0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
E0051603biological_processproteolysis involved in protein catabolic process
F0000502cellular_componentproteasome complex
F0003674molecular_functionmolecular_function
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005839cellular_componentproteasome core complex
F0006511biological_processubiquitin-dependent protein catabolic process
F0010499biological_processproteasomal ubiquitin-independent protein catabolic process
F0019773cellular_componentproteasome core complex, alpha-subunit complex
F0034515cellular_componentproteasome storage granule
F0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
F0051603biological_processproteolysis involved in protein catabolic process
G0000502cellular_componentproteasome complex
G0003729molecular_functionmRNA binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0005839cellular_componentproteasome core complex
G0006511biological_processubiquitin-dependent protein catabolic process
G0010499biological_processproteasomal ubiquitin-independent protein catabolic process
G0019773cellular_componentproteasome core complex, alpha-subunit complex
G0034515cellular_componentproteasome storage granule
G0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
G0051603biological_processproteolysis involved in protein catabolic process
N0000502cellular_componentproteasome complex
N0004175molecular_functionendopeptidase activity
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0006511biological_processubiquitin-dependent protein catabolic process
N0008540cellular_componentproteasome regulatory particle, base subcomplex
N0030234molecular_functionenzyme regulator activity
N0031625molecular_functionubiquitin protein ligase binding
N0034515cellular_componentproteasome storage granule
N0042176biological_processregulation of protein catabolic process
N0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
N0043248biological_processproteasome assembly
O0000502cellular_componentproteasome complex
O0005198molecular_functionstructural molecule activity
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005829cellular_componentcytosol
O0006511biological_processubiquitin-dependent protein catabolic process
O0008541cellular_componentproteasome regulatory particle, lid subcomplex
O0034515cellular_componentproteasome storage granule
O0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
O0043248biological_processproteasome assembly
P0000338biological_processprotein deneddylation
P0000502cellular_componentproteasome complex
P0005515molecular_functionprotein binding
P0005737cellular_componentcytoplasm
P0008180cellular_componentCOP9 signalosome
P0008541cellular_componentproteasome regulatory particle, lid subcomplex
P0034515cellular_componentproteasome storage granule
P0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Q0000502cellular_componentproteasome complex
Q0005198molecular_functionstructural molecule activity
Q0005515molecular_functionprotein binding
Q0006511biological_processubiquitin-dependent protein catabolic process
Q0008541cellular_componentproteasome regulatory particle, lid subcomplex
Q0034515cellular_componentproteasome storage granule
Q0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Q0043248biological_processproteasome assembly
R0000502cellular_componentproteasome complex
R0005198molecular_functionstructural molecule activity
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005838cellular_componentproteasome regulatory particle
R0006511biological_processubiquitin-dependent protein catabolic process
R0008541cellular_componentproteasome regulatory particle, lid subcomplex
R0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
S0000502cellular_componentproteasome complex
S0003674molecular_functionmolecular_function
S0005515molecular_functionprotein binding
S0006511biological_processubiquitin-dependent protein catabolic process
S0008541cellular_componentproteasome regulatory particle, lid subcomplex
S0030234molecular_functionenzyme regulator activity
S0042176biological_processregulation of protein catabolic process
S0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
T0000502cellular_componentproteasome complex
T0003674molecular_functionmolecular_function
T0005515molecular_functionprotein binding
T0005634cellular_componentnucleus
T0005838cellular_componentproteasome regulatory particle
T0006508biological_processproteolysis
T0006511biological_processubiquitin-dependent protein catabolic process
T0008541cellular_componentproteasome regulatory particle, lid subcomplex
T0034515cellular_componentproteasome storage granule
T0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
U0000502cellular_componentproteasome complex
U0005515molecular_functionprotein binding
U0005838cellular_componentproteasome regulatory particle
U0006511biological_processubiquitin-dependent protein catabolic process
U0008233molecular_functionpeptidase activity
U0008237molecular_functionmetallopeptidase activity
U0008541cellular_componentproteasome regulatory particle, lid subcomplex
U0034515cellular_componentproteasome storage granule
U0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
V0000266biological_processmitochondrial fission
V0000502cellular_componentproteasome complex
V0004843molecular_functioncysteine-type deubiquitinase activity
V0005515molecular_functionprotein binding
V0005634cellular_componentnucleus
V0005739cellular_componentmitochondrion
V0005829cellular_componentcytosol
V0006508biological_processproteolysis
V0008233molecular_functionpeptidase activity
V0008234molecular_functioncysteine-type peptidase activity
V0008237molecular_functionmetallopeptidase activity
V0008270molecular_functionzinc ion binding
V0008541cellular_componentproteasome regulatory particle, lid subcomplex
V0016559biological_processperoxisome fission
V0016579biological_processprotein deubiquitination
V0034515cellular_componentproteasome storage granule
V0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
V0043248biological_processproteasome assembly
V0046872molecular_functionmetal ion binding
V0070628molecular_functionproteasome binding
V0140492molecular_functionmetal-dependent deubiquitinase activity
V1902906biological_processproteasome storage granule assembly
W0000502cellular_componentproteasome complex
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005829cellular_componentcytosol
W0006511biological_processubiquitin-dependent protein catabolic process
W0008540cellular_componentproteasome regulatory particle, base subcomplex
W0031593molecular_functionpolyubiquitin modification-dependent protein binding
W0036435molecular_functionK48-linked polyubiquitin modification-dependent protein binding
W0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
W0043248biological_processproteasome assembly
X0000502cellular_componentproteasome complex
X0005515molecular_functionprotein binding
X0005634cellular_componentnucleus
X0005737cellular_componentcytoplasm
X0006511biological_processubiquitin-dependent protein catabolic process
X0008541cellular_componentproteasome regulatory particle, lid subcomplex
X0034515cellular_componentproteasome storage granule
X0043130molecular_functionubiquitin binding
X0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Y0000502cellular_componentproteasome complex
Y0000724biological_processdouble-strand break repair via homologous recombination
Y0003674molecular_functionmolecular_function
Y0005515molecular_functionprotein binding
Y0005829cellular_componentcytosol
Y0006406biological_processmRNA export from nucleus
Y0006457biological_processprotein folding
Y0006511biological_processubiquitin-dependent protein catabolic process
Y0008541cellular_componentproteasome regulatory particle, lid subcomplex
Y0030447biological_processfilamentous growth
Y0034515cellular_componentproteasome storage granule
Y0035753biological_processmaintenance of DNA trinucleotide repeats
Y0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
Y0043248biological_processproteasome assembly
Y0044183molecular_functionprotein folding chaperone
Y0045944biological_processpositive regulation of transcription by RNA polymerase II
Y0051726biological_processregulation of cell cycle
Y0060090molecular_functionmolecular adaptor activity
Y0070390cellular_componenttranscription export complex 2
Y0072742biological_processSAGA complex localization to transcription regulatory region
Z0000502cellular_componentproteasome complex
Z0004175molecular_functionendopeptidase activity
Z0005515molecular_functionprotein binding
Z0005634cellular_componentnucleus
Z0005737cellular_componentcytoplasm
Z0005783cellular_componentendoplasmic reticulum
Z0006511biological_processubiquitin-dependent protein catabolic process
Z0008540cellular_componentproteasome regulatory particle, base subcomplex
Z0030234molecular_functionenzyme regulator activity
Z0030674molecular_functionprotein-macromolecule adaptor activity
Z0034515cellular_componentproteasome storage granule
Z0042176biological_processregulation of protein catabolic process
Z0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
a0000502cellular_componentproteasome complex
a0003674molecular_functionmolecular_function
a0005515molecular_functionprotein binding
a0005634cellular_componentnucleus
a0005737cellular_componentcytoplasm
a0005739cellular_componentmitochondrion
a0005839cellular_componentproteasome core complex
a0006511biological_processubiquitin-dependent protein catabolic process
a0010499biological_processproteasomal ubiquitin-independent protein catabolic process
a0019773cellular_componentproteasome core complex, alpha-subunit complex
a0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
a0051603biological_processproteolysis involved in protein catabolic process
b0000502cellular_componentproteasome complex
b0003674molecular_functionmolecular_function
b0005515molecular_functionprotein binding
b0005634cellular_componentnucleus
b0005737cellular_componentcytoplasm
b0005839cellular_componentproteasome core complex
b0006511biological_processubiquitin-dependent protein catabolic process
b0010499biological_processproteasomal ubiquitin-independent protein catabolic process
b0019773cellular_componentproteasome core complex, alpha-subunit complex
b0034515cellular_componentproteasome storage granule
b0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
b0051603biological_processproteolysis involved in protein catabolic process
c0000502cellular_componentproteasome complex
c0003674molecular_functionmolecular_function
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005737cellular_componentcytoplasm
c0005829cellular_componentcytosol
c0005839cellular_componentproteasome core complex
c0006511biological_processubiquitin-dependent protein catabolic process
c0010499biological_processproteasomal ubiquitin-independent protein catabolic process
c0019773cellular_componentproteasome core complex, alpha-subunit complex
c0034515cellular_componentproteasome storage granule
c0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
c0051603biological_processproteolysis involved in protein catabolic process
c0080129biological_processproteasome core complex assembly
d0000502cellular_componentproteasome complex
d0003674molecular_functionmolecular_function
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005737cellular_componentcytoplasm
d0005739cellular_componentmitochondrion
d0005839cellular_componentproteasome core complex
d0006511biological_processubiquitin-dependent protein catabolic process
d0010499biological_processproteasomal ubiquitin-independent protein catabolic process
d0019773cellular_componentproteasome core complex, alpha-subunit complex
d0034515cellular_componentproteasome storage granule
d0042175cellular_componentnuclear outer membrane-endoplasmic reticulum membrane network
d0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
d0051603biological_processproteolysis involved in protein catabolic process
e0000502cellular_componentproteasome complex
e0003674molecular_functionmolecular_function
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005737cellular_componentcytoplasm
e0005839cellular_componentproteasome core complex
e0006511biological_processubiquitin-dependent protein catabolic process
e0010499biological_processproteasomal ubiquitin-independent protein catabolic process
e0019773cellular_componentproteasome core complex, alpha-subunit complex
e0034515cellular_componentproteasome storage granule
e0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
e0051603biological_processproteolysis involved in protein catabolic process
f0000502cellular_componentproteasome complex
f0003674molecular_functionmolecular_function
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005737cellular_componentcytoplasm
f0005839cellular_componentproteasome core complex
f0006511biological_processubiquitin-dependent protein catabolic process
f0010499biological_processproteasomal ubiquitin-independent protein catabolic process
f0019773cellular_componentproteasome core complex, alpha-subunit complex
f0034515cellular_componentproteasome storage granule
f0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
f0051603biological_processproteolysis involved in protein catabolic process
g0000502cellular_componentproteasome complex
g0003729molecular_functionmRNA binding
g0005515molecular_functionprotein binding
g0005634cellular_componentnucleus
g0005737cellular_componentcytoplasm
g0005839cellular_componentproteasome core complex
g0006511biological_processubiquitin-dependent protein catabolic process
g0010499biological_processproteasomal ubiquitin-independent protein catabolic process
g0019773cellular_componentproteasome core complex, alpha-subunit complex
g0034515cellular_componentproteasome storage granule
g0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
g0051603biological_processproteolysis involved in protein catabolic process
h0000502cellular_componentproteasome complex
h0004175molecular_functionendopeptidase activity
h0004298molecular_functionthreonine-type endopeptidase activity
h0005515molecular_functionprotein binding
h0005634cellular_componentnucleus
h0005737cellular_componentcytoplasm
h0005829cellular_componentcytosol
h0005839cellular_componentproteasome core complex
h0006508biological_processproteolysis
h0010499biological_processproteasomal ubiquitin-independent protein catabolic process
h0019774cellular_componentproteasome core complex, beta-subunit complex
h0034515cellular_componentproteasome storage granule
h0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
h0051603biological_processproteolysis involved in protein catabolic process
i0000502cellular_componentproteasome complex
i0004175molecular_functionendopeptidase activity
i0004298molecular_functionthreonine-type endopeptidase activity
i0005515molecular_functionprotein binding
i0005634cellular_componentnucleus
i0005737cellular_componentcytoplasm
i0005829cellular_componentcytosol
i0005839cellular_componentproteasome core complex
i0006508biological_processproteolysis
i0010499biological_processproteasomal ubiquitin-independent protein catabolic process
i0019774cellular_componentproteasome core complex, beta-subunit complex
i0034515cellular_componentproteasome storage granule
i0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
i0051603biological_processproteolysis involved in protein catabolic process
j0000502cellular_componentproteasome complex
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005737cellular_componentcytoplasm
j0005829cellular_componentcytosol
j0005839cellular_componentproteasome core complex
j0010499biological_processproteasomal ubiquitin-independent protein catabolic process
j0019774cellular_componentproteasome core complex, beta-subunit complex
j0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
j0051603biological_processproteolysis involved in protein catabolic process
j0061133molecular_functionendopeptidase activator activity
k0000502cellular_componentproteasome complex
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005737cellular_componentcytoplasm
k0005789cellular_componentendoplasmic reticulum membrane
k0005829cellular_componentcytosol
k0005839cellular_componentproteasome core complex
k0010498biological_processproteasomal protein catabolic process
k0010499biological_processproteasomal ubiquitin-independent protein catabolic process
k0019774cellular_componentproteasome core complex, beta-subunit complex
k0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
k0051603biological_processproteolysis involved in protein catabolic process
k0061133molecular_functionendopeptidase activator activity
l0000502cellular_componentproteasome complex
l0004175molecular_functionendopeptidase activity
l0004298molecular_functionthreonine-type endopeptidase activity
l0005515molecular_functionprotein binding
l0005634cellular_componentnucleus
l0005737cellular_componentcytoplasm
l0005777cellular_componentperoxisome
l0005829cellular_componentcytosol
l0005839cellular_componentproteasome core complex
l0006508biological_processproteolysis
l0010499biological_processproteasomal ubiquitin-independent protein catabolic process
l0019774cellular_componentproteasome core complex, beta-subunit complex
l0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
l0051603biological_processproteolysis involved in protein catabolic process
l0080129biological_processproteasome core complex assembly
m0000502cellular_componentproteasome complex
m0003674molecular_functionmolecular_function
m0005515molecular_functionprotein binding
m0005634cellular_componentnucleus
m0005737cellular_componentcytoplasm
m0005829cellular_componentcytosol
m0005839cellular_componentproteasome core complex
m0010499biological_processproteasomal ubiquitin-independent protein catabolic process
m0019774cellular_componentproteasome core complex, beta-subunit complex
m0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
m0051603biological_processproteolysis involved in protein catabolic process
n0000502cellular_componentproteasome complex
n0003674molecular_functionmolecular_function
n0005515molecular_functionprotein binding
n0005634cellular_componentnucleus
n0005737cellular_componentcytoplasm
n0005829cellular_componentcytosol
n0005839cellular_componentproteasome core complex
n0010499biological_processproteasomal ubiquitin-independent protein catabolic process
n0019774cellular_componentproteasome core complex, beta-subunit complex
n0034515cellular_componentproteasome storage granule
n0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
n0043248biological_processproteasome assembly
n0051603biological_processproteolysis involved in protein catabolic process
Functional Information from PROSITE/UniProt
site_idPS00387
Number of Residues7
DetailsPPASE Inorganic pyrophosphatase signature. DDDEIDV
ChainResidueDetails
UASP243-VAL249

site_idPS00388
Number of Residues23
DetailsPROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdgdtVtFSPtGRlfQVEYAleA
ChainResidueDetails
fTYR6-ALA28
aTYR12-ALA34
cTYR6-SER28
eTYR8-ALA30
gTYR8-ALA30
dTYR4-ALA26
bTYR5-ALA27

site_idPS00854
Number of Residues48
DetailsPROTEASOME_BETA_1 Proteasome beta-type subunits signature. ISMkYdnGVIIAADnlgsygsllrfngve.RlipvgdntvvgisGdiSD
ChainResidueDetails
7ILE45-ASP92
jVAL13-ASP59
iVAL33-ASP80
kLEU5-ASP52
6LEU21-ASP68
cILE36-ASP83
dVAL34-ASP81
lLEU79-ASP126
hMET13-ASP60

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000269|PubMed:12504901
ChainResidueDetails
USER2
RSER77
VASP122
cLYS231
CLYS100
CLYS199
CLYS231

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19779198
ChainResidueDetails
USER314
USER317
3LYS70

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:19779198
ChainResidueDetails
USER319
XSER140
ALYS232

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19779198
ChainResidueDetails
UTHR327
ZSER695

Catalytic Information from CSA
site_idMCSA1
Number of Residues8
DetailsM-CSA 177
ChainResidueDetails
iTHR30covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
iASP46activator, steric locator
iARG48activator
iLYS62activator, electrostatic stabiliser
iGLY76electrostatic stabiliser
iSER158activator, electrostatic stabiliser
iASP195activator, steric locator
iSER198activator, electrostatic stabiliser

site_idMCSA2
Number of Residues8
DetailsM-CSA 177
ChainResidueDetails
2THR30covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor
2ASP46activator, steric locator
2ARG48activator
2LYS62activator, electrostatic stabiliser
2GLY76electrostatic stabiliser
2SER158activator, electrostatic stabiliser
2ASP195activator, steric locator
2SER198activator, electrostatic stabiliser

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PDB entries from 2024-11-06

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