7QO6

26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state

This is a non-PDB format compatible entry.

Summary for 7QO6

• Entry DOI: 10.2210/pdb7qo6/pdb
• EMDB information: 14085
• Descriptor: BJ4_G0020160.mRNA.1.CDS.1, Proteasome endopeptidase complex, Proteasome subunit beta, ... (38 entities in total)
• Functional Keywords: proteasome, ubiquitin, ubp6, allostery, deubiquitination, motor protein
• Biological source: Saccharomyces cerevisiae (baker's yeast); More
• Total number of polymer chains: 49
• Total formula weight: 1761616.46

Authors

Hung, K.Y.S.,Klumpe, S.,Eisele, M.R.,Elsasser, S.,Geng, T.T.,Cheng, T.C.,Joshi, T.,Rudack, T.,Sakata, E.,Finley, D. (deposition date: 2021-12-23, release date: 2022-03-16, Last modification date: 2022-07-20)

• Primary citation: Hung, K.Y.S.,Klumpe, S.,Eisele, M.R.,Elsasser, S.,Tian, G.,Sun, S.,Moroco, J.A.,Cheng, T.C.,Joshi, T.,Seibel, T.,Van Dalen, D.,Feng, X.H.,Lu, Y.,Ovaa, H.,Engen, J.R.,Lee, B.H.,Rudack, T.,Sakata, E.,Finley, D.; Allosteric control of Ubp6 and the proteasome via a bidirectional switch.; Nat Commun, 13:838-838, 2022; PubMed: 35149681; DOI: 10.1038/s41467-022-28186-y

Experimental method

ELECTRON MICROSCOPY (6.3 Å)