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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7QO6

26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1a, ABJ4_G0020160.mRNA.1.CDS.1polymer25228033.82UniProt (A0A6A5PYC9)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)HLJ1_G0019920.mRNA.1.CDS.1,Proteasome subunit alpha type-1
2b, BHLJ1_G0039880.mRNA.1.CDS.1polymer25027191.82UniProt (A0A6L1BIF8)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome subunit alpha type-2
3c, CBJ4_G0021480.mRNA.1.CDS.1polymer25828748.22UniProt (A0A6A5PXC6)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome subunit alpha type-3
4d, DHLJ1_G0048980.mRNA.1.CDS.1polymer25428478.12UniProt (A0A6A5Q273)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome subunit alpha type-4
5e, EEM14S01-3B_G0035190.mRNA.1.CDS.1polymer26028649.12UniProt (A0A6A5PXN2)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)HLJ1_G0035780.mRNA.1.CDS.1,Proteasome subunit alpha type-5,SX2_G0040870.mRNA.1.CDS.1,XXYS1_4_G0037780.mRNA.1.CDS.1,Y55_G0035760.mRNA.1.CDS.1
6f, FBJ4_G0043800.mRNA.1.CDS.1polymer23425634.02UniProt (A0A6A5PTH4)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome subunit alpha type-6
7g, GProbable proteasome subunit alpha type-7polymer28831575.12UniProt (A0A6A5Q4M4)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)
8h, 1Proteasome subunit beta type-1polymer21523573.62UniProt (P38624)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3
9i, 2Proteasome endopeptidase complexpolymer26128299.92UniProt (A0A6A5Q449)
Pfam (PF00227)
Pfam (PF12465)
In PDB		Saccharomyces cerevisiae (baker's yeast)
10j, 3Proteasome endopeptidase complexpolymer20522627.82UniProt (A0A6L0YA22)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)
11k, 4Proteasome subunit betapolymer19822545.72UniProt (A0A6A5Q0W2)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)
12l, 5Proteasome subunit beta type-5polymer28731670.52UniProt (A0A6A5Q5W3)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)
13m, 6HLJ1_G0013750.mRNA.1.CDS.1polymer24126905.12UniProt (A0A6A5Q0P3)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome subunit beta type-6,SX2_G0013730.mRNA.1.CDS.1,Y55_G0013890.mRNA.1.CDS.1
14n, 7Proteasome subunit beta type-7polymer26629471.32UniProt (P30657)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4
15W26S proteasome regulatory subunit RPN10polymer26829776.11UniProt (A0A6A5PUA1)
Pfam (PF13519)
In PDB		Saccharomyces cerevisiae (baker's yeast)
16V26S proteasome regulatory subunit RPN11polymer30634442.31UniProt (A0A6A5PWR8)
Pfam (PF01398)
In PDB		Saccharomyces cerevisiae (baker's yeast)
17TEM14S01-3B_G0050020.mRNA.1.CDS.1polymer27431952.11UniProt (A0A7I9BXZ7)
Pfam (PF10075)
In PDB		Saccharomyces cerevisiae (baker's yeast)Y55_G0050750.mRNA.1.CDS.1
18XHLJ1_G0030700.mRNA.1.CDS.1polymer15617919.01UniProt (A0A6A5PTW0)
Pfam (PF04683)
In PDB		Saccharomyces cerevisiae (baker's yeast)HN1_G0030480.mRNA.1.CDS.1,SX2_G0030420.mRNA.1.CDS.1
19Y26S proteasome complex subunit SEM1polymer8910397.11UniProt (O94742)
Pfam (PF05160)
In PDB		Saccharomyces cerevisiae (baker's yeast)
20Z26S proteasome regulatory subunit RPN1polymer993109601.91UniProt (P38764)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
In PDB		Saccharomyces cerevisiae (baker's yeast)HMG-CoA reductase degradation protein 2,Proteasome non-ATPase subunit 1
21N26S proteasome regulatory subunit RPN2polymer945104351.91UniProt (P32565)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
In PDB		Saccharomyces cerevisiae (baker's yeast)
22S26S proteasome regulatory subunit RPN3polymer52360464.61UniProt (A0A6L1AUZ6)
Pfam (PF01399)
Pfam (PF08375)
In PDB		Saccharomyces cerevisiae (baker's yeast)SX2_G0000950.mRNA.1.CDS.1
23P26S proteasome regulatory subunit RPN5polymer44551840.41UniProt (A0A6A5PYX7)
Pfam (PF22241)
Pfam (PF01399)
Pfam (PF18098)
In PDB		Saccharomyces cerevisiae (baker's yeast)HLJ1_G0042390.mRNA.1.CDS.1,SX2_G0042290.mRNA.1.CDS.1
24Q26S proteasome regulatory subunit RPN6polymer43449839.81UniProt (A0A6L0YP93)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
In PDB		Saccharomyces cerevisiae (baker's yeast)EM14S01-3B_G0042150.mRNA.1.CDS.1,HLJ1_G0042890.mRNA.1.CDS.1,HN1_G0042730.mRNA.1.CDS.1,Y55_G0042740.mRNA.1.CDS.1
25R26S proteasome regulatory subunit RPN7polymer42949016.41UniProt (A0A6A5Q2N6)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
In PDB		Saccharomyces cerevisiae (baker's yeast)
26U26S proteasome regulatory subunit RPN8polymer33838365.51UniProt (Q08723)
Pfam (PF01398)
Pfam (PF13012)
In PDB		Saccharomyces cerevisiae (baker's yeast)
27O26S proteasome regulatory subunit RPN9polymer39345839.31UniProt (Q04062)
Pfam (PF22037)
Pfam (PF01399)
Pfam (PF18261)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome non-ATPase subunit 7
28H26S proteasome regulatory subunit 7 homologpolymer46752153.11UniProt (A0A6A5PV22)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)HLJ1_G0003420.mRNA.1.CDS.1,HN1_G0003390.mRNA.1.CDS.1,SX2_G0003430.mRNA.1.CDS.1,Y55_G0003630.mRNA.1.CDS.1
29I26S proteasome regulatory subunit 4 homologpolymer43748898.21UniProt (A0A6A5Q382)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)EM14S01-3B_G0043310.mRNA.1.CDS.1,HLJ1_G0043690.mRNA.1.CDS.1,HN1_G0043500.mRNA.1.CDS.1,SX2_G0043570.mRNA.1.CDS.1,Y55_G0043530.mRNA.1.CDS.1
30K26S proteasome regulatory subunit 6B homologpolymer42847953.71UniProt (A0A6A5PYF7)
Pfam (PF16450)
Pfam (PF00004)
In PDB		Saccharomyces cerevisiae (baker's yeast)EM14S01-3B_G0046630.mRNA.1.CDS.1,HLJ1_G0047490.mRNA.1.CDS.1,HN1_G0047230.mRNA.1.CDS.1,SX2_G0047320.mRNA.1.CDS.1,XXYS1_4_G0049230.mRNA.1.CDS.1,Y55_G0047290.mRNA.1.CDS.1
31L26S proteasome subunit RPT4polymer43749480.11UniProt (A0A6A5Q8D3)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)HLJ1_G0040220.mRNA.1.CDS.1,HN1_G0040040.mRNA.1.CDS.1,SX2_G0034800.mRNA.1.CDS.1,Y55_G0040060.mRNA.1.CDS.1
32M26S proteasome regulatory subunit 6Apolymer43448315.71UniProt (A0A6A5Q672)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)HLJ1_G0038940.mRNA.1.CDS.1,HN1_G0038760.mRNA.1.CDS.1,SX2_G0033520.mRNA.1.CDS.1,Y55_G0038760.mRNA.1.CDS.1
33J26S proteasome regulatory subunit 8 homologpolymer40545342.71UniProt (A0A6A5PWS2)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)EM14S01-3B_G0032480.mRNA.1.CDS.1,HLJ1_G0032990.mRNA.1.CDS.1,HN1_G0032830.mRNA.1.CDS.1,SX2_G0038120.mRNA.1.CDS.1,XXYS1_4_G0035060.mRNA.1.CDS.1,Y55_G0032950.mRNA.1.CDS.1
348Ubiquitin carboxyl-terminal hydrolasepolymer49957188.61UniProt (A0A6A5PXS0)
Pfam (PF00443)
In PDB		Saccharomyces cerevisiae (baker's yeast)
359Polyubiquitin-Bpolymer768560.81UniProt (J3QS39)
Pfam (PF00240)
In PDB		Homo sapiens (human)
36K, L, M, H, IADENOSINE-5'-TRIPHOSPHATEnon-polymer507.25Chemie (ATP)
37I, K, L, M, J...MAGNESIUM IONnon-polymer24.36Chemie (MG)
38JADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence modifications
H: 1 - 467 (UniProt: A0A6A5PV22)
PDBExternal DatabaseDetails
Arg 164Ser 164variant
Lys 166Thr 166variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains49
Total formula weight1758507.5
Non-Polymers*Number of molecules12
Total formula weight3108.9
All*Total formula weight1761616.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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