7QO6
26S proteasome Rpt1-RK -Ubp6-UbVS complex in the s2 state
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, O (a, A) | BJ4_G0020160.mRNA.1.CDS.1 | polymer | 252 | 28033.8 | 2 | UniProt (A0A6A5PYC9) | Saccharomyces cerevisiae (baker's yeast) | HLJ1_G0019920.mRNA.1.CDS.1,Proteasome subunit alpha type-1 |
| 2 | B, P (b, B) | HLJ1_G0039880.mRNA.1.CDS.1 | polymer | 250 | 27191.8 | 2 | UniProt (A0A6L1BIF8) | Saccharomyces cerevisiae (baker's yeast) | Proteasome subunit alpha type-2 |
| 3 | C, Q (c, C) | BJ4_G0021480.mRNA.1.CDS.1 | polymer | 258 | 28748.2 | 2 | UniProt (A0A6A5PXC6) | Saccharomyces cerevisiae (baker's yeast) | Proteasome subunit alpha type-3 |
| 4 | D, R (d, D) | HLJ1_G0048980.mRNA.1.CDS.1 | polymer | 254 | 28478.1 | 2 | UniProt (A0A6A5Q273) | Saccharomyces cerevisiae (baker's yeast) | Proteasome subunit alpha type-4 |
| 5 | E, S (e, E) | EM14S01-3B_G0035190.mRNA.1.CDS.1 | polymer | 260 | 28649.1 | 2 | UniProt (A0A6A5PXN2) | Saccharomyces cerevisiae (baker's yeast) | HLJ1_G0035780.mRNA.1.CDS.1,Proteasome subunit alpha type-5,SX2_G0040870.mRNA.1.CDS.1,XXYS1_4_G0037780.mRNA.1.CDS.1,Y55_G0035760.mRNA.1.CDS.1 |
| 6 | F, T (f, F) | BJ4_G0043800.mRNA.1.CDS.1 | polymer | 234 | 25634.0 | 2 | UniProt (A0A6A5PTH4) | Saccharomyces cerevisiae (baker's yeast) | Proteasome subunit alpha type-6 |
| 7 | G, U (g, G) | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (A0A6A5Q4M4) | Saccharomyces cerevisiae (baker's yeast) | |
| 8 | H, V (h, 1) | Proteasome subunit beta type-1 | polymer | 215 | 23573.6 | 2 | UniProt (P38624) Pfam (PF00227) | Saccharomyces cerevisiae (baker's yeast) | Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
| 9 | I, W (i, 2) | Proteasome endopeptidase complex | polymer | 261 | 28299.9 | 2 | UniProt (A0A6A5Q449) | Saccharomyces cerevisiae (baker's yeast) | |
| 10 | J, X (j, 3) | Proteasome endopeptidase complex | polymer | 205 | 22627.8 | 2 | UniProt (A0A6L0YA22) | Saccharomyces cerevisiae (baker's yeast) | |
| 11 | K, Y (k, 4) | Proteasome subunit beta | polymer | 198 | 22545.7 | 2 | UniProt (A0A6A5Q0W2) | Saccharomyces cerevisiae (baker's yeast) | |
| 12 | L, Z (l, 5) | Proteasome subunit beta type-5 | polymer | 287 | 31670.5 | 2 | UniProt (A0A6A5Q5W3) | Saccharomyces cerevisiae (baker's yeast) | |
| 13 | AA, M (m, 6) | HLJ1_G0013750.mRNA.1.CDS.1 | polymer | 241 | 26905.1 | 2 | UniProt (A0A6A5Q0P3) | Saccharomyces cerevisiae (baker's yeast) | Proteasome subunit beta type-6,SX2_G0013730.mRNA.1.CDS.1,Y55_G0013890.mRNA.1.CDS.1 |
| 14 | BA, N (n, 7) | Proteasome subunit beta type-7 | polymer | 266 | 29471.3 | 2 | UniProt (P30657) Pfam (PF00227) | Saccharomyces cerevisiae (baker's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
| 15 | CA (W) | 26S proteasome regulatory subunit RPN10 | polymer | 268 | 29776.1 | 1 | UniProt (A0A6A5PUA1) | Saccharomyces cerevisiae (baker's yeast) | |
| 16 | DA (V) | 26S proteasome regulatory subunit RPN11 | polymer | 306 | 34442.3 | 1 | UniProt (A0A6A5PWR8) | Saccharomyces cerevisiae (baker's yeast) | |
| 17 | EA (T) | EM14S01-3B_G0050020.mRNA.1.CDS.1 | polymer | 274 | 31952.1 | 1 | UniProt (A0A7I9BXZ7) | Saccharomyces cerevisiae (baker's yeast) | Y55_G0050750.mRNA.1.CDS.1 |
| 18 | FA (X) | HLJ1_G0030700.mRNA.1.CDS.1 | polymer | 156 | 17919.0 | 1 | UniProt (A0A6A5PTW0) | Saccharomyces cerevisiae (baker's yeast) | HN1_G0030480.mRNA.1.CDS.1,SX2_G0030420.mRNA.1.CDS.1 |
| 19 | GA (Y) | 26S proteasome complex subunit SEM1 | polymer | 89 | 10397.1 | 1 | UniProt (O94742) Pfam (PF05160) | Saccharomyces cerevisiae (baker's yeast) | |
| 20 | HA (Z) | 26S proteasome regulatory subunit RPN1 | polymer | 993 | 109601.9 | 1 | UniProt (P38764) Pfam (PF17781) Pfam (PF01851) Pfam (PF18051) | Saccharomyces cerevisiae (baker's yeast) | HMG-CoA reductase degradation protein 2,Proteasome non-ATPase subunit 1 |
| 21 | IA (N) | 26S proteasome regulatory subunit RPN2 | polymer | 945 | 104351.9 | 1 | UniProt (P32565) Pfam (PF21505) Pfam (PF01851) Pfam (PF13646) Pfam (PF18004) | Saccharomyces cerevisiae (baker's yeast) | |
| 22 | JA (S) | 26S proteasome regulatory subunit RPN3 | polymer | 523 | 60464.6 | 1 | UniProt (A0A6L1AUZ6) | Saccharomyces cerevisiae (baker's yeast) | SX2_G0000950.mRNA.1.CDS.1 |
| 23 | KA (P) | 26S proteasome regulatory subunit RPN5 | polymer | 445 | 51840.4 | 1 | UniProt (A0A6A5PYX7) | Saccharomyces cerevisiae (baker's yeast) | HLJ1_G0042390.mRNA.1.CDS.1,SX2_G0042290.mRNA.1.CDS.1 |
| 24 | LA (Q) | 26S proteasome regulatory subunit RPN6 | polymer | 434 | 49839.8 | 1 | UniProt (A0A6L0YP93) | Saccharomyces cerevisiae (baker's yeast) | EM14S01-3B_G0042150.mRNA.1.CDS.1,HLJ1_G0042890.mRNA.1.CDS.1,HN1_G0042730.mRNA.1.CDS.1,Y55_G0042740.mRNA.1.CDS.1 |
| 25 | MA (R) | 26S proteasome regulatory subunit RPN7 | polymer | 429 | 49016.4 | 1 | UniProt (A0A6A5Q2N6) | Saccharomyces cerevisiae (baker's yeast) | |
| 26 | NA (U) | 26S proteasome regulatory subunit RPN8 | polymer | 338 | 38365.5 | 1 | UniProt (Q08723) Pfam (PF01398) Pfam (PF13012) | Saccharomyces cerevisiae (baker's yeast) | |
| 27 | OA (O) | 26S proteasome regulatory subunit RPN9 | polymer | 393 | 45839.3 | 1 | UniProt (Q04062) Pfam (PF22037) Pfam (PF01399) Pfam (PF18261) | Saccharomyces cerevisiae (baker's yeast) | Proteasome non-ATPase subunit 7 |
| 28 | PA (H) | 26S proteasome regulatory subunit 7 homolog | polymer | 467 | 52153.1 | 1 | UniProt (A0A6A5PV22) | Saccharomyces cerevisiae (baker's yeast) | HLJ1_G0003420.mRNA.1.CDS.1,HN1_G0003390.mRNA.1.CDS.1,SX2_G0003430.mRNA.1.CDS.1,Y55_G0003630.mRNA.1.CDS.1 |
| 29 | QA (I) | 26S proteasome regulatory subunit 4 homolog | polymer | 437 | 48898.2 | 1 | UniProt (A0A6A5Q382) | Saccharomyces cerevisiae (baker's yeast) | EM14S01-3B_G0043310.mRNA.1.CDS.1,HLJ1_G0043690.mRNA.1.CDS.1,HN1_G0043500.mRNA.1.CDS.1,SX2_G0043570.mRNA.1.CDS.1,Y55_G0043530.mRNA.1.CDS.1 |
| 30 | RA (K) | 26S proteasome regulatory subunit 6B homolog | polymer | 428 | 47953.7 | 1 | UniProt (A0A6A5PYF7) | Saccharomyces cerevisiae (baker's yeast) | EM14S01-3B_G0046630.mRNA.1.CDS.1,HLJ1_G0047490.mRNA.1.CDS.1,HN1_G0047230.mRNA.1.CDS.1,SX2_G0047320.mRNA.1.CDS.1,XXYS1_4_G0049230.mRNA.1.CDS.1,Y55_G0047290.mRNA.1.CDS.1 |
| 31 | SA (L) | 26S proteasome subunit RPT4 | polymer | 437 | 49480.1 | 1 | UniProt (A0A6A5Q8D3) | Saccharomyces cerevisiae (baker's yeast) | HLJ1_G0040220.mRNA.1.CDS.1,HN1_G0040040.mRNA.1.CDS.1,SX2_G0034800.mRNA.1.CDS.1,Y55_G0040060.mRNA.1.CDS.1 |
| 32 | TA (M) | 26S proteasome regulatory subunit 6A | polymer | 434 | 48315.7 | 1 | UniProt (A0A6A5Q672) | Saccharomyces cerevisiae (baker's yeast) | HLJ1_G0038940.mRNA.1.CDS.1,HN1_G0038760.mRNA.1.CDS.1,SX2_G0033520.mRNA.1.CDS.1,Y55_G0038760.mRNA.1.CDS.1 |
| 33 | UA (J) | 26S proteasome regulatory subunit 8 homolog | polymer | 405 | 45342.7 | 1 | UniProt (A0A6A5PWS2) | Saccharomyces cerevisiae (baker's yeast) | EM14S01-3B_G0032480.mRNA.1.CDS.1,HLJ1_G0032990.mRNA.1.CDS.1,HN1_G0032830.mRNA.1.CDS.1,SX2_G0038120.mRNA.1.CDS.1,XXYS1_4_G0035060.mRNA.1.CDS.1,Y55_G0032950.mRNA.1.CDS.1 |
| 34 | VA (8) | Ubiquitin carboxyl-terminal hydrolase | polymer | 499 | 57188.6 | 1 | UniProt (A0A6A5PXS0) | Saccharomyces cerevisiae (baker's yeast) | |
| 35 | WA (9) | Polyubiquitin-B | polymer | 76 | 8560.8 | 1 | UniProt (J3QS39) Pfam (PF00240) | Homo sapiens (human) | |
| 36 | BB, DB, FB, XA, ZA (K, L, M, H, I) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
| 37 | AB, CB, EB, GB, IB... (I, K, L, M, J...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
| 38 | HB (J) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
H: 1 - 467 (UniProt: A0A6A5PV22)
| PDB | External Database | Details |
|---|---|---|
| Arg 164 | Ser 164 | variant |
| Lys 166 | Thr 166 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 49 |
| Total formula weight | 1758507.5 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3108.9 | |
| All* | Total formula weight | 1761616.5 |
