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7K0O
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 3
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0K
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, 3KS-bound
分子名称: 3-Dehydrosphinganine, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0N
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 2
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0J
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa protomer
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0Q
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, myriocin-bound
分子名称: Myriocin, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0L
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa, myriocin-bound
分子名称: Myriocin, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0P
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Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 4
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0I
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BU of 7k0i by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, PYRIDOXAL-5'-PHOSPHATE, Serine palmitoyltransferase 1, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
7K0M
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BU of 7k0m by Molmil
Human serine palmitoyltransferase complex SPTLC1/SPLTC2/ssSPTa/ORMDL3, class 1
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ORM1-like protein 3, PYRIDOXAL-5'-PHOSPHATE, ...
著者Wang, Y, Niu, Y, Zhang, Z, Zhao, H, Myasnikov, A, Kalathur, R, Lee, C.H.
登録日2020-09-04
公開日2021-02-24
最終更新日2021-03-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into the regulation of human serine palmitoyltransferase complexes.
Nat.Struct.Mol.Biol., 28, 2021
8WZX
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BU of 8wzx by Molmil
Cryo-EM structure of the hamster prion 23-144 fibril at pH 3.7
分子名称: Major prion protein
著者Lee, C.-H, Saw, J.-E, Chen, E, Wang, C.-H, Chen, R.
登録日2023-11-02
公開日2024-05-01
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献The Positively Charged Cluster in the N-terminal Disordered Region may Affect Prion Protein Misfolding: Cryo-EM Structure of Hamster PrP(23-144) Fibrils.
J.Mol.Biol., 436, 2024
1EFN
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BU of 1efn by Molmil
HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN
分子名称: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION
著者Lee, C.-H, Kuriyan, J.
登録日1996-06-29
公開日1997-01-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.
Cell(Cambridge,Mass.), 85, 1996
6UQF
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BU of 6uqf by Molmil
Human HCN1 channel in a hyperpolarized conformation
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, MERCURY (II) ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lee, C.-H, MacKinnon, R.
登録日2019-10-19
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
6UQG
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BU of 6uqg by Molmil
Human HCN1 channel Y289D mutant
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lee, C.-H, MacKinnon, R.
登録日2019-10-19
公開日2019-12-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Cell, 179, 2019
1AYC
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BU of 1ayc by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE PDGFR-740, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYA
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BU of 1aya by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE PDGFR-1009, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYB
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BU of 1ayb by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PEPTIDE IRS-1-895, PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
1AYD
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BU of 1ayd by Molmil
CRYSTAL STRUCTURES OF PEPTIDE COMPLEXES OF THE AMINO-TERMINAL SH2 DOMAIN OF THE SYP TYROSINE PHOSPHATASE
分子名称: PROTEIN-TYROSINE PHOSPHATASE SYP (N-TERMINAL SH2 DOMAIN)
著者Lee, C.-H, Kuriyan, J.
登録日1994-05-15
公開日1994-08-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of peptide complexes of the amino-terminal SH2 domain of the Syp tyrosine phosphatase.
Structure, 2, 1994
4TLL
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BU of 4tll by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 1
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
著者Gouaux, E, Lee, C.-H, Lu, W.
登録日2014-05-30
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
4TLM
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BU of 4tlm by Molmil
Crystal structure of GluN1/GluN2B NMDA receptor, structure 2
分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-[(1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-methylpropyl]phenol, ...
著者Gouaux, E, Lee, C.-H, Lu, W.
登録日2014-05-30
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.77 Å)
主引用文献NMDA receptor structures reveal subunit arrangement and pore architecture.
Nature, 511, 2014
5V4E
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BU of 5v4e by Molmil
Engineered human IgG Fc domain glyco801 (Fc801)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-09
公開日2017-06-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.216 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5V43
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BU of 5v43 by Molmil
Engineered human IgG Fc domain aglyco801
分子名称: Ig gamma-1 chain C region
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-08
公開日2017-06-21
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5U6O
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BU of 5u6o by Molmil
Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel
分子名称: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
著者Lee, C.-H, MacKinnon, R.
登録日2016-12-08
公開日2017-01-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
5U6P
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Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11
著者Lee, C.-H, MacKinnon, R.
登録日2016-12-08
公開日2017-01-25
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.51 Å)
主引用文献Structures of the Human HCN1 Hyperpolarization-Activated Channel.
Cell, 168, 2017
8ZMR
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Vesamicol-bound VAChT
分子名称: Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7, vesamicol
著者Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H.
登録日2024-05-23
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into VAChT neurotransmitter recognition and inhibition.
Cell Res., 34, 2024
8ZMS
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Acetylcholine-bound VAChT
分子名称: ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7
著者Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H.
登録日2024-05-23
公開日2024-06-19
最終更新日2024-09-18
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into VAChT neurotransmitter recognition and inhibition.
Cell Res., 34, 2024

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