5U6P
Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Summary for 5U6P
Entry DOI | 10.2210/pdb5u6p/pdb |
Related | 5U6O |
EMDB information | 8511 8512 |
Descriptor | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total) |
Functional Keywords | pacemaker ion channel, transport protein |
Biological source | Homo sapiens (Human) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : O60741 |
Total number of polymer chains | 8 |
Total formula weight | 306431.78 |
Authors | Lee, C.-H.,MacKinnon, R. (deposition date: 2016-12-08, release date: 2017-01-25, Last modification date: 2024-03-13) |
Primary citation | Lee, C.H.,MacKinnon, R. Structures of the Human HCN1 Hyperpolarization-Activated Channel. Cell, 168:111-120.e11, 2017 Cited by PubMed: 28086084DOI: 10.1016/j.cell.2016.12.023 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.51 Å) |
Structure validation
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