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5U6P

Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, B, C, D)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11polymer66074643.74UniProt (O60741)
Pfam (PF08412)
Pfam (PF00520)
Pfam (PF00027)
Homo sapiens (Human)Brain cyclic nucleotide-gated channel 1, BCNG-1
2B, D, F, H
(E, F, G, H)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11polymer191635.04Homo sapiens (Human)Brain cyclic nucleotide-gated channel 1
3I, J, K, L
(A, B, C, D)
ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATEnon-polymer329.24Chemie (CMP)
Sequence modifications
A, B, C, D: 1 - 635 (UniProt: O60741)
A, B, C, D: 636 - 660 (UniProt: O60741)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight305115.0
Non-Polymers*Number of molecules4
Total formula weight1316.8
All*Total formula weight306431.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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