5U6P

Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, B, C, D)	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11	polymer	660	74643.7	4	UniProt (O60741) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027)	Homo sapiens (Human)	Brain cyclic nucleotide-gated channel 1, BCNG-1
2	B, D, F, H (E, F, G, H)	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11	polymer	19	1635.0	4		Homo sapiens (Human)	Brain cyclic nucleotide-gated channel 1
3	I, J, K, L (A, B, C, D)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP) PubChem (23902375) PubChem (25322948) PubChem (176488666) PubChem (25322946) PubChem (40467852) PubChem (59350541) PubChem (44629928) PubChem (274) PubChem (6604194) PubChem (56973690) PubChem (163043517) PubChem (59909322) PubChem (59968988) PubChem (70878457) PubChem (6076) PubChem (124132380) PubChem (216878) PubChem (3080770) PubChem (3246347) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (129317551) PubChem (12071879) PubChem (12866365) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (163043518)

Sequence modifications

A, B, C, D: 1 - 635 (UniProt: O60741)
A, B, C, D: 636 - 660 (UniProt: O60741)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	305115.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	306431.8

*Water molecules are not included.