5U6P

Structure of the human HCN1 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11	polymer	660	74643.7	4	UniProt (O60741) Pfam (PF08412) Pfam (PF00520) Pfam (PF00027) In PDB	Homo sapiens (Human)	Brain cyclic nucleotide-gated channel 1, BCNG-1
2	E, F, G, H	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 11	polymer	19	1635.0	4		Homo sapiens (Human)	Brain cyclic nucleotide-gated channel 1
3	A, B, C, D	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)

Sequence modifications

A, B, C, D: 1 - 635 (UniProt: O60741)
A, B, C, D: 636 - 660 (UniProt: O60741)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	305115.0
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	306431.8

*Water molecules are not included.