8DLB
| Room temperature X-ray structure of SARS-CoV-2 main protease in complex with compound Z2799209083 | 分子名称: | 1-[(5S)-5-(3,4-dimethoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethan-1-one, 3C-like proteinase | 著者 | Kovalevsky, A.Y, Coates, L, Kneller, D.W. | 登録日 | 2022-07-07 | 公開日 | 2023-05-17 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2. J.Chem.Inf.Model., 63, 2023
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8DMD
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8DL9
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3GV3
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2PVP
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3CF9
| Crystal structure of (3R)-Hydroxyacyl-Acyl Carrier Protein Dehydratase (FabZ) from Helicobacter pylori in complex with apigenin | 分子名称: | (3R)-hydroxymyristoyl-acyl carrier protein dehydratase, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one, BENZAMIDINE, ... | 著者 | Zhang, L, Wu, D, Liu, W, Shen, X, Jiang, H. | 登録日 | 2008-03-03 | 公開日 | 2008-12-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Three flavonoids targeting the beta-hydroxyacyl-acyl carrier protein dehydratase from Helicobacter pylori: crystal structure characterization with enzymatic inhibition assay Protein Sci., 17, 2008
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3VFF
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3VFH
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8P6Q
| Racemic structure of TNFR1 cysteine-rich domain | 分子名称: | D-TNFR-1 CRD2, SULFATE ION, Tumor necrosis factor-binding protein 1 | 著者 | Lander, A.J, Jin, Y, Luk, L.Y.P. | 登録日 | 2023-05-28 | 公開日 | 2024-01-24 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Deciphering the Synthetic and Refolding Strategy of a Cysteine-Rich Domain in the Tumor Necrosis Factor Receptor (TNF-R) for Racemic Crystallography Analysis and d-Peptide Ligand Discovery. Acs Bio Med Chem Au, 4, 2024
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8P36
| Neisseria meningitidis Type IV pilus SB-DATDH variant | 分子名称: | 2,4-bisacetamido-2,4,6-trideoxy-beta-D-glucopyranose, Neisseria meningitidis PilE, SB-DATDH variant, ... | 著者 | Fernandez-Martinez, D, Dumenil, G. | 登録日 | 2023-05-17 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms. Nat Commun, 15, 2024
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8PJP
| Neisseria meningitidis PilE, SB-GATDH variant, bound to the F10 nanobody | 分子名称: | (2~{R})-~{N}-[(2~{R},3~{S},4~{S},5~{R},6~{R})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide, Nanobody F10, Pilin, ... | 著者 | Fernandez-Martinez, D, Dumenil, G. | 登録日 | 2023-06-23 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms. Nat Commun, 15, 2024
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8PIZ
| Neisseria meningitidis Type IV pilus SB-DATDH variant bound to the C24 nanobody | 分子名称: | 2,4-bisacetamido-2,4,6-trideoxy-beta-D-glucopyranose, C24 nanobody, Pilin, ... | 著者 | Fernandez-Martinez, D, Dumenil, G. | 登録日 | 2023-06-22 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms. Nat Commun, 15, 2024
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8P2V
| Neisseria meningitidis Type IV pilus SB-GATDH variant | 分子名称: | (2~{R})-~{N}-[(2~{R},3~{S},4~{S},5~{R},6~{R})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide, Neisseria meningitidis PilE variant SB-GATDH, SN-GLYCEROL-3-PHOSPHATE | 著者 | Fernandez-Martinez, D, Dumenil, G. | 登録日 | 2023-05-16 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms. Nat Commun, 15, 2024
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8P3B
| Neisseria meningitidis Type IV pilus SA-GATDH variant | 分子名称: | (2~{R})-~{N}-[(2~{R},3~{S},4~{S},5~{R},6~{R})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide, Fimbrial protein, SN-GLYCEROL-3-PHOSPHATE | 著者 | Fernandez-Martinez, D, Dumenil, G. | 登録日 | 2023-05-17 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms. Nat Commun, 15, 2024
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8PIJ
| Neisseria meningitidis Type IV pilus SB-GATDH variant bound to the C24 nanobody | 分子名称: | (2~{R})-~{N}-[(2~{R},3~{S},4~{S},5~{R},6~{R})-5-acetamido-2-methyl-4,6-bis(oxidanyl)oxan-3-yl]-2,3-bis(oxidanyl)propanamide, C24 nanobody, Pilin, ... | 著者 | Fernandez-Martinez, D, Dumenil, G. | 登録日 | 2023-06-21 | 公開日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms. Nat Commun, 15, 2024
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3SBE
| Crystal structure of RAC1 P29S mutant | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2011-06-03 | 公開日 | 2012-07-18 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44, 2012
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3SBD
| Crystal structure of RAC1 P29S mutant | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2011-06-03 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44, 2012
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3TH5
| Crystal structure of wild-type RAC1 | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related C3 botulinum toxin substrate 1 | 著者 | Ha, B.H, Boggon, T.J. | 登録日 | 2011-08-18 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat.Genet., 44, 2012
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8IGZ
| Xcc NAMPT Quadruple mutant | 分子名称: | Pre-B cell enhancing factor related protein | 著者 | Xu, G.L, Ming, Z.H. | 登録日 | 2023-02-21 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | 主引用文献 | Structural insights into Xanthomonas campestris pv. campestris NAD + biosynthesis via the NAM salvage pathway. Commun Biol, 7, 2024
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8I79
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7WHI
| The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2021-12-30 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
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7WHJ
| The state 1 complex structure of Omicron spike with Bn03 (1-up RBD, 3 nanobodies) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2021-12-30 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
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7WHK
| The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Bn03_nano1, Bn03_nano2, ... | 著者 | Zhan, W.Q, Zhang, X, Chen, Z.G, Sun, L. | 登録日 | 2021-12-30 | 公開日 | 2022-05-11 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody. Cell, 185, 2022
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7VSW
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7VSU
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