8E1P
| Crystal structure of BG505 SOSIP.v4.1-GT1.2 trimer in complex with gl-PGV20 and PGT124 Fabs | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505-SOSIP.v4.1-GT1.2gp120, ... | 著者 | Sarkar, A, Kumar, S, Wilson, I.A. | 登録日 | 2022-08-11 | 公開日 | 2023-06-21 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.82 Å) | 主引用文献 | Germline-targeting HIV-1 Env vaccination induces VRC01-class antibodies with rare insertions. Cell Rep Med, 4, 2023
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7XYT
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8U1D
| Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env Local Refinement | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1285 Heavy Chain, DH1285 Light Chain, ... | 著者 | Thakur, B, Stalls, V.D, Acharya, P. | 登録日 | 2023-08-31 | 公開日 | 2024-01-03 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | 主引用文献 | Vaccine induction of CD4-mimicking HIV-1 broadly neutralizing antibody precursors in macaques. Cell, 187, 2024
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7LAB
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7LAA
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7LD1
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7LCN
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5C7M
| CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | 分子名称: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | 著者 | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2015-06-24 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
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5C7J
| CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | 分子名称: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | 著者 | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | 登録日 | 2015-06-24 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes. Mol.Cell, 62, 2016
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7XYV
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7XYW
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7XYX
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7XYS
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7XYU
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5UKP
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5UKN
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5UKR
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5UKO
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5UKQ
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7YNX
| Crystal structure of Pirh2 bound to poly-Ala peptide | 分子名称: | RING finger and CHY zinc finger domain-containing protein 1, SODIUM ION, SULFATE ION, ... | 著者 | Dong, C, Yan, X, Li, Y. | 登録日 | 2022-08-01 | 公開日 | 2023-04-26 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Recognition of an Ala-rich C-degron by the E3 ligase Pirh2. Nat Commun, 14, 2023
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7LJR
| SARS-CoV-2 Spike Protein Trimer bound to DH1043 fab | 分子名称: | Fab DH1043 heavy chain, Fab DH1043 light chain, Spike glycoprotein | 著者 | Gobeil, S, Acharya, P. | 登録日 | 2021-01-30 | 公開日 | 2021-03-31 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | 主引用文献 | The functions of SARS-CoV-2 neutralizing and infection-enhancing antibodies in vitro and in mice and nonhuman primates. Biorxiv, 2021
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6UM5
| Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Acharya, P, Henderson, R.C, Saunders, K.O, Haynes, B.F. | 登録日 | 2019-10-09 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
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6UM6
| Cryo-EM structure of HIV-1 neutralizing antibody DH270.6 in complex with CH848 10.17DT Env | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Acharya, P, Henderson, R.C, Saunder, K.O, Haynes, B.F. | 登録日 | 2019-10-09 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
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6UM7
| Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH270.mu1 Fab Heavy Chain, DH270.mu1 Fab Light chain, ... | 著者 | Acharya, P, Henderson, R.C, Saunders, K, Haynes, B.F. | 登録日 | 2019-10-09 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science, 366, 2019
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6WLF
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