2GFJ
| Crystal structure of the zinc-beta-lactamase L1 from stenotrophomonas maltophilia (inhibitor 1) | 分子名称: | 1,3-DIPHENYL-1H-PYRAZOLE-4,5-DICARBOXYLIC ACID, Metallo-beta-lactamase L1, SULFATE ION, ... | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | 登録日 | 2006-03-22 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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2H6A
| Crystal structure of the zinc-beta-lactamase L1 from Stenotrophomonas maltophilia (mono zinc form) | 分子名称: | Metallo-beta-lactamase L1, SULFATE ION, ZINC ION | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | 登録日 | 2006-05-31 | 公開日 | 2007-04-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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3ZVT
| Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | 分子名称: | 2,6 DIMETHOXYBENZAMIDOBORONIC ACID, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, ... | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | 登録日 | 2011-07-27 | 公開日 | 2012-02-29 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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3ZVW
| Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3,3-DIMETHYLBUTAN-1-OL, ACETONE, ... | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | 登録日 | 2011-07-28 | 公開日 | 2012-02-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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5CGS
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5CGX
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F complexed with cefoxitin | 分子名称: | (2R)-2-{(1S)-1-methoxy-2-oxo-1-[(thiophen-2-ylacetyl)amino]ethyl}-5-methylidene-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase, SODIUM ION, ... | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.21 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
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5CGW
| CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | 登録日 | 2015-07-09 | 公開日 | 2016-02-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function. Antimicrob.Agents Chemother., 2015
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1BSG
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2CC1
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1XPB
| STRUCTURE OF BETA-LACTAMASE TEM1 | 分子名称: | BETA-LACTAMASE, SULFATE ION | 著者 | Fonze, E, Charlier, P. | 登録日 | 1997-01-10 | 公開日 | 1997-04-01 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant. Acta Crystallogr.,Sect.D, 51, 1995
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2GMN
| Crystal structure of BJP-1, a subclass B3 metallo-beta-lactamase of Bradyrhizobium japonicum | 分子名称: | Metallo-beta-lactamase, ZINC ION | 著者 | Calderone, V, Benvenuti, M, Stoczko, M, Docquier, J.D, Rossolini, G.M, Mangani, S. | 登録日 | 2006-04-07 | 公開日 | 2007-04-24 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Postgenomic scan of metallo-beta-lactamase homologues in rhizobacteria: identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum. Antimicrob.Agents Chemother., 50, 2006
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2J9P
| Crystal structure of the Bacillus subtilis PBP4a, and its complex with a peptidoglycan mimetic peptide. | 分子名称: | (2R)-2-AMINO-7-{[(1R)-1-CARBOXYETHYL]AMINO}-7-OXOHEPTANOIC ACID, D-ALANINE, D-alanyl-D-alanine carboxypeptidase DacC | 著者 | Sauvage, E, Herman, R, Kerff, F, Duez, C, Charlier, P. | 登録日 | 2006-11-15 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of the Bacillus subtilis penicillin-binding protein 4a, and its complex with a peptidoglycan mimetic peptide. J. Mol. Biol., 371, 2007
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1M2X
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1J9M
| K38H mutant of Streptomyces K15 DD-transpeptidase | 分子名称: | CHLORIDE ION, DD-transpeptidase, SODIUM ION | 著者 | Fonze, E, Rhazi, N, Nguyen-Disteche, M, Charlier, P. | 登録日 | 2001-05-28 | 公開日 | 2001-06-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Catalytic mechanism of the Streptomyces K15 DD-transpeptidase/penicillin-binding protein probed by site-directed mutagenesis and structural analysis. Biochemistry, 42, 2003
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2HP9
| Crystal Structure of the OXA-10 W154A mutant at pH 6.0 | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | 登録日 | 2006-07-17 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2HPB
| Crystal structure of the OXA-10 W154A mutant at pH 9.0 | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | 登録日 | 2006-07-17 | 公開日 | 2007-07-03 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2HP5
| Crystal Structure of the OXA-10 W154G mutant at pH 7.0 | 分子名称: | Beta-lactamase PSE-2, COBALT (II) ION, SULFATE ION | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | 登録日 | 2006-07-17 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2HP6
| Crystal structure of the OXA-10 W154A mutant at pH 7.5 | 分子名称: | Beta-lactamase PSE-2, SULFATE ION | 著者 | Kerff, F, Falzone, C, Herman, R, Sauvage, E, Charlier, P. | 登録日 | 2006-07-17 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases. Biochemistry, 48, 2009
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2WGW
| Crystal structure of the OXA-10 V117T mutant at pH 8.0 | 分子名称: | BETA-LACTAMASE OXA-10, GLYCEROL, SULFATE ION | 著者 | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | 登録日 | 2009-04-27 | 公開日 | 2010-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2WKI
| Crystal structure of the OXA-10 K70C mutant at pH 7.0 | 分子名称: | 1,2-ETHANEDIOL, BETA-LACTAMASE OXA-10, GLYCEROL, ... | 著者 | Vercheval, L, Bauvois, C, Kerff, F, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | 登録日 | 2009-06-11 | 公開日 | 2010-08-25 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post-Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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2WKX
| Crystal structure of the native E. coli zinc amidase AmiD | 分子名称: | CHLORIDE ION, GLYCEROL, N-ACETYLMURAMOYL-L-ALANINE AMIDASE AMID, ... | 著者 | Petrella, S, Kerff, F, Herman, R, Genereux, C, Pennartz, A, Sauvage, E, Joris, B, Charlier, P. | 登録日 | 2009-06-18 | 公開日 | 2010-01-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Specific Structural Features of the N-Acetylmuramoyl-L-Alanine Amidase Amid from Escherichia Coli and Mechanistic Implications for Enzymes of This Family. J.Mol.Biol., 397, 2010
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2WHG
| Crystal Structure of the Di-Zinc Metallo-beta-lactamase VIM-4 from Pseudomonas aeruginosa | 分子名称: | CITRATE ANION, VIM-4 METALLO-BETA-LACTAMASE, ZINC ION | 著者 | Lassaux, P, Traore, D.A.K, Galleni, M, Ferrer, J.L. | 登録日 | 2009-05-05 | 公開日 | 2010-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Biochemical and Structural Characterization of the Subclass B1 Metallo-{Beta}-Lactamase Vim-4. Antimicrob.Agents Chemother., 55, 2011
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2WGI
| Crystal structure of the acyl-enzyme OXA-10 W154A-benzylpenicillin at pH 6 | 分子名称: | BETA-LACTAMASE OXA-10, GLYCEROL, OPEN FORM - PENICILLIN G | 著者 | Vercheval, L, Falzone, C, Sauvage, E, Herman, R, Charlier, P, Galleni, M, Kerff, F. | 登録日 | 2009-04-20 | 公開日 | 2009-11-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Critical Role of Tryptophan 154 for the Activity and Stability of Class D Beta-Lactamases. Biochemistry, 48, 2009
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2Y4A
| Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein | 分子名称: | D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, MAGNESIUM ION, SULFATE ION, ... | 著者 | Sauvage, E, Zervosen, A, Herman, R, Kerff, F, Rocaboy, M, Charlier, P. | 登録日 | 2011-01-05 | 公開日 | 2011-07-27 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Unexpected Tricovalent Binding Mode of Boronic Acids within the Active Site of a Penicillin- Binding Protein. J.Am.Chem.Soc., 133, 2011
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2WGV
| Crystal structure of the OXA-10 V117T mutant at pH 6.5 inhibited by a chloride ion | 分子名称: | BETA-LACTAMASE OXA-10, CHLORIDE ION, CITRIC ACID, ... | 著者 | Vercheval, L, Kerff, F, Bauvois, C, Sauvage, E, Guiet, R, Charlier, P, Galleni, M. | 登録日 | 2009-04-27 | 公開日 | 2010-05-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Three Factors that Modulate the Activity of Class D Beta-Lactamases and Interfere with the Post- Translational Carboxylation of Lys70. Biochem.J., 432, 2010
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