2HP5

Crystal Structure of the OXA-10 W154G mutant at pH 7.0

Summary for 2HP5

• Entry DOI: 10.2210/pdb2hp5/pdb
• Related: 1K4F 2HP6 2HP9 2HPB
• Descriptor: Beta-lactamase PSE-2, SULFATE ION, COBALT (II) ION, ... (4 entities in total)
• Functional Keywords: class d beta-lactamase, lysine carboxylation, hydrolase
• Biological source: Pseudomonas aeruginosa
• Total number of polymer chains: 4
• Total formula weight: 111529.89

Authors

Kerff, F.,Falzone, C.,Herman, R.,Sauvage, E.,Charlier, P. (deposition date: 2006-07-17, release date: 2007-07-03, Last modification date: 2023-08-30)

• Primary citation: Baurin, S.,Vercheval, L.,Bouillenne, F.,Falzone, C.,Brans, A.,Jacquamet, L.,Ferrer, J.L.,Sauvage, E.,Dehareng, D.,Frere, J.M.,Charlier, P.,Galleni, M.,Kerff, F.; Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases.; Biochemistry, 48:11252-11263, 2009; PubMed: 19860471; DOI: 10.1021/bi901548c

Experimental method

X-RAY DIFFRACTION (2.7 Å)