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7B1J
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BU of 7b1j by Molmil
Orthorhombic P21212 Structure of Human Mad1 C-terminal Domain in Complex with Phosphorylated Bub1 CD1 Domain
分子名称: Mitotic checkpoint serine/threonine-protein kinase BUB1, Mitotic spindle assembly checkpoint protein MAD1
著者Fischer, E, Bellini, D, Barford, D.
登録日2020-11-25
公開日2021-03-17
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Molecular mechanism of Mad1 kinetochore targeting by phosphorylated Bub1.
Embo Rep., 22, 2021
4S1K
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BU of 4s1k by Molmil
Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 100 K
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Polyhedrin
著者Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I.
登録日2015-01-14
公開日2015-03-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.
Nat Commun, 6, 2015
4S1L
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BU of 4s1l by Molmil
Structure of Uranotaenia sapphirina cypovirus (CPV17) polyhedrin at 298 K
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, polyhedrin
著者Ginn, H.M, Messerschmidt, M, Ji, X, Zhang, H, Axford, D, Gildea, R.J, Winter, G, Brewster, A.S, Hattne, J, Wagner, A, Grimes, J.M, Evans, G, Sauter, N.K, Sutton, G, Stuart, D.I.
登録日2015-01-14
公開日2015-03-25
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.752 Å)
主引用文献Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data.
Nat Commun, 6, 2015
4UI9
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BU of 4ui9 by Molmil
Atomic structure of the human Anaphase-Promoting Complex
分子名称: ANAPHASE-PROMOTING COMPLEX SUBUNIT 1, ANAPHASE-PROMOTING COMPLEX SUBUNIT 10, ANAPHASE-PROMOTING COMPLEX SUBUNIT 11, ...
著者Chang, L, Zhang, Z, Yang, J, McLaughlin, S.H, Barford, D.
登録日2015-03-27
公開日2015-06-17
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Atomic Structure of the Apc and its Mechanism of Protein Ubiquitination
Nature, 522, 2015
6YPC
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BU of 6ypc by Molmil
Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9 angstroms
分子名称: Inner kinetochore subunit CNN1, Inner kinetochore subunit CTF3, Inner kinetochore subunit MCM16, ...
著者Bellini, D, Zhang, Z, Barford, D.
登録日2020-04-15
公開日2020-09-16
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the Cenp-HIKHead-TW sub-module of the inner kinetochore CCAN complex.
Nucleic Acids Res., 48, 2020
2BGG
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BU of 2bgg by Molmil
The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex.
分子名称: 5'-R(*GP*UP*CP*GP*AP*AP*UP*UP)-3', 5'-R(*UP*UP*CP*GP*AP*CP*GP*CP)-3', MANGANESE (II) ION, ...
著者Parker, J.S, Roe, S.M, Barford, D.
登録日2004-12-22
公開日2005-03-31
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Insights Into Mrna Recognition from a Piwi Domain-Sirna Guide Complex
Nature, 434, 2005
8QV0
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BU of 8qv0 by Molmil
Structure of the native microtubule lattice nucleated from the yeast spindle pole body
分子名称: Tubulin alpha-1 chain, Tubulin beta chain
著者Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D.
登録日2023-10-17
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (6.6 Å)
主引用文献Structure of the native gamma-tubulin ring complex capping spindle microtubules.
Nat.Struct.Mol.Biol., 2024
7YWX
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BU of 7ywx by Molmil
Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein C, Centromere protein H, Centromere protein I, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-14
公開日2022-05-18
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7YYH
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BU of 7yyh by Molmil
Structure of the human CCANdeltaT CENP-A alpha-satellite complex
分子名称: Centromere protein C, Centromere protein H, Centromere protein I, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-17
公開日2022-05-18
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (8.9 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7R5S
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BU of 7r5s by Molmil
Structure of the human CCAN bound to alpha satellite DNA
分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7R5R
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BU of 7r5r by Molmil
Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein C, DNA (171-MER), Histone H2A type 1-C, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.44 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
7R5V
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BU of 7r5v by Molmil
Structure of the human CCAN CENP-A alpha-satellite complex
分子名称: Centromere protein H, Centromere protein I, Centromere protein K, ...
著者Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D.
登録日2022-02-11
公開日2022-04-27
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (4.55 Å)
主引用文献Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
8QV3
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BU of 8qv3 by Molmil
Structure of the y-Tubulin Small Complex (yTuSC) as part of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body
分子名称: GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, Spindle pole body component 110, ...
著者Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D.
登録日2023-10-17
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (8.2 Å)
主引用文献Structure of the native gamma-tubulin ring complex capping spindle microtubules.
Nat.Struct.Mol.Biol., 2024
8QV2
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BU of 8qv2 by Molmil
Structure of the native y-Tubulin Ring Complex (yTuRC) capping microtubule minus ends at the spindle pole body
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Spindle pole body component, ...
著者Dendooven, T, Yatskevich, S, Burt, A, Bellini, D, Kilmartin, J, Barford, D.
登録日2023-10-17
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (9.2 Å)
主引用文献Structure of the native gamma-tubulin ring complex capping spindle microtubules.
Nat.Struct.Mol.Biol., 2024
8QRY
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BU of 8qry by Molmil
Crystal structure of the yeast spindle body component Spc98
分子名称: Spindle pole body component
著者Bellini, D, Yatskevich, S, Barford, D.
登録日2023-10-09
公開日2024-04-03
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal structure of the yeast spindle body component Spc98
To Be Published
8PPR
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BU of 8ppr by Molmil
Structure of the human outer kinetochore KMN network complex
分子名称: Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ...
著者Yatskevich, S, Barford, D.
登録日2023-07-08
公開日2024-03-20
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the human outer kinetochore KMN network complex.
Nat.Struct.Mol.Biol., 31, 2024
1BZC
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BU of 1bzc by Molmil
HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH TPI
分子名称: 4-CARBAMOYL-4-{[6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBONYL]-AMINO}-BUTYRIC ACID, PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE)
著者Groves, M.R, Yao, Z.J, Jr Burke, T.R, Barford, D.
登録日1998-10-27
公開日1999-02-16
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
2W9N
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BU of 2w9n by Molmil
crystal structure of linear di-ubiquitin
分子名称: CHLORIDE ION, UBIQUITIN, ZINC ION
著者Komander, D, Reyes-Turcu, F, Wilkinson, K.D, Barford, D.
登録日2009-01-27
公開日2009-04-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Molecular Discrimination of Structurally Equivalent Lys 63-Linked and Linear Polyubiquitin Chains.
Embo Rep., 10, 2009
2VFJ
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BU of 2vfj by Molmil
Structure of the A20 Ovarian Tumour (OTU) domain
分子名称: MAGNESIUM ION, SULFATE ION, TUMOR NECROSIS FACTOR
著者Komander, D, Barford, D.
登録日2007-11-04
公開日2007-12-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of the A20 Otu Domain and Mechanistic Insights Into Deubiquitination
Biochem.J., 409, 2008
2V55
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BU of 2v55 by Molmil
Mechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structure
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Komander, D, Garg, R, Wan, P.T.C, Ridley, A.J, Barford, D.
登録日2008-10-01
公開日2008-11-04
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.705 Å)
主引用文献Mechanism of Multi-Site Phosphorylation from a Rock-I:Rhoe Complex Structure.
Embo J., 27, 2008
2VHF
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BU of 2vhf by Molmil
Structure of the CYLD USP domain
分子名称: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD, ZINC ION
著者Komander, D, Lord, C.J, Scheel, H, Swift, S, Hofmann, K, Ashworth, A, Barford, D.
登録日2007-11-21
公開日2008-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Cyld Usp Domain Explains its Specificity for Lys63-Linked Polyubiquitin and Reveals a B-Box Module
Mol.Cell.Biol., 29, 2008
6QLE
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BU of 6qle by Molmil
Structure of inner kinetochore CCAN complex
分子名称: Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3,Central kinetochore subunit CTF3,Inner kinetochore subunit CTF3, Central kinetochore subunit MCM16,Central kinetochore subunit MCM16,Inner kinetochore subunit MCM16,Mcm16p, Inner kinetochore subunit AME1,Inner kinetochore subunit AME1,Inner kinetochore subunit AME1,Inner kinetochore subunit AME1, ...
著者Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
登録日2019-01-31
公開日2019-10-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
6QLD
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BU of 6qld by Molmil
Structure of inner kinetochore CCAN-Cenp-A complex
分子名称: DNA (125-MER), Histone H2A.1, Histone H2B.1, ...
著者Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
登録日2019-01-31
公開日2019-10-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.15 Å)
主引用文献Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019
1BZH
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BU of 1bzh by Molmil
Cyclic peptide inhibitor of human PTP1B
分子名称: PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B)
著者Groves, M.R, Yao, Z.J, Burke Jr, T.R, Barford, D.
登録日1998-10-28
公開日1999-02-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.
Biochemistry, 37, 1998
6QLF
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BU of 6qlf by Molmil
Structure of inner kinetochore CCAN complex with mask1
分子名称: Inner kinetochore subunit AME1, Inner kinetochore subunit CHL4, Inner kinetochore subunit CTF19, ...
著者Yan, K, Yang, J, Zhang, Z, McLaughlin, S.H, Chang, L, Fasci, D, Heck, A.J.R, Barford, D.
登録日2019-01-31
公開日2019-10-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献Structure of the inner kinetochore CCAN complex assembled onto a centromeric nucleosome.
Nature, 574, 2019

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