5FIA
 
 | | Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LpiR1 | | 著者 | Beyrakhova, K, van Straaten, K, Cygler, M. | | 登録日 | 2015-12-22 | | 公開日 | 2016-01-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila.
J.Biol.Chem., 291, 2016
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1CRL
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1AC5
 | | CRYSTAL STRUCTURE OF KEX1(DELTA)P, A PROHORMONE-PROCESSING CARBOXYPEPTIDASE FROM SACCHAROMYCES CEREVISIAE | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, KEX1(DELTA)P | | 著者 | Shilton, B.H, Thomas, D.Y, Cygler, M. | | 登録日 | 1997-02-13 | | 公開日 | 1997-05-15 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of Kex1deltap, a prohormone-processing carboxypeptidase from Saccharomyces cerevisiae.
Biochemistry, 36, 1997
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1DEU
 | | CRYSTAL STRUCTURE OF HUMAN PROCATHEPSIN X: A CYSTEINE PROTEASE WITH THE PROREGION COVALENTLY LINKED TO THE ACTIVE SITE CYSTEINE | | 分子名称: | PROCATHEPSIN X | | 著者 | Sivaraman, J, Nagler, D.K, Zhang, R, Menard, R, Cygler, M. | | 登録日 | 1999-11-15 | | 公開日 | 2000-02-18 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
J.Mol.Biol., 295, 2000
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1DBO
 | | CRYSTAL STRUCTURE OF CHONDROITINASE B | | 分子名称: | 4-deoxy-alpha-D-glucopyranose-(1-3)-[beta-D-glucopyranose-(1-4)]2-O-methyl-beta-L-fucopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-2)-[alpha-L-rhamnopyranose-(1-4)]alpha-D-mannopyranose, 4-deoxy-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose, CHONDROITINASE B | | 著者 | Huang, W, Matte, A, Li, Y, Kim, Y.S, Linhardt, R.J, Su, H, Cygler, M. | | 登録日 | 1999-11-03 | | 公開日 | 2000-01-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of chondroitinase B from Flavobacterium heparinum and its complex with a disaccharide product at 1.7 A resolution.
J.Mol.Biol., 294, 1999
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4FZW
 | | Crystal Structure of the PaaF-PaaG Hydratase-Isomerase Complex from E.coli | | 分子名称: | 1,2-epoxyphenylacetyl-CoA isomerase, 2,3-dehydroadipyl-CoA hydratase, GLYCEROL | | 著者 | Grishin, A.M, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2012-07-08 | | 公開日 | 2012-09-19 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Protein-Protein Interactions in the beta-Oxidation Part of the Phenylacetate
Utilization Pathway. Crystal Structure of the PaaF-PaaG Hydratase-Isomerase Complex
J.Biol.Chem., 287, 2012
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6W1D
 | | Structure of human mitochondrial complex Nfs1-ISCU2 (WT)-ISD11 with E.coli ACP1 at 1.8 A resolution (NIAU)2 | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | | 著者 | Boniecki, M.T, Cygler, M. | | 登録日 | 2020-03-04 | | 公開日 | 2020-03-18 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | | 主引用文献 | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
To Be Published
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6WI2
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6WIH
 | | N-terminal mutation of ISCU2 (L35H36) traps Nfs1 Cys loop in the active site of ISCU2 without metal present. Structure of human mitochondrial complex Nfs1-ISCU2(L35H36)-ISD11 with E.coli ACP1 at 1.9 A resolution (NIAU)2. | | 分子名称: | 1,2-ETHANEDIOL, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, Acyl carrier protein, ... | | 著者 | Boniecki, M.T, Cygler, M. | | 登録日 | 2020-04-09 | | 公開日 | 2020-05-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
To Be Published
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5JMF
 | | Heparinase III-BT4657 gene product | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, Heparinase III protein, ... | | 著者 | Ulaganathan, T.S, Shi, R, Yao, D, Garron, M.-L, Cherney, M, Cygler, M. | | 登録日 | 2016-04-28 | | 公開日 | 2016-05-25 | | 最終更新日 | 2018-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | | 主引用文献 | Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657).
Glycobiology, 27, 2017
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5JMD
 | | Heparinase III-BT4657 gene product, Methylated Lysines | | 分子名称: | Heparinase III protein, MAGNESIUM ION | | 著者 | Ulaganathan, T.S, Shi, R, Yao, D, Garron, M.-L, Cherney, M, Cygler, M. | | 登録日 | 2016-04-28 | | 公開日 | 2016-05-25 | | 最終更新日 | 2018-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657).
Glycobiology, 27, 2017
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7RTK
 | | Structure of the (NIAU)2 complex with N-terminal mutation of ISCU2 Y35D at 2.5 A resolution | | 分子名称: | 1,2-ETHANEDIOL, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ... | | 著者 | Boniecki, M.T, Cygler, M. | | 登録日 | 2021-08-13 | | 公開日 | 2021-08-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The essential function of ISCU2 and its conserved N-terminus in Fe/S cluster biogenesis
To Be Published
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6MCQ
 | | L. pneumophila effector kinase LegK7 in complex with human MOB1A | | 分子名称: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | | 著者 | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | | 登録日 | 2018-09-01 | | 公開日 | 2019-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6MCP
 | | L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A | | 分子名称: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, LegK7, ... | | 著者 | Beyrakhova, K.A, Xu, C, Boniecki, M.T, Cygler, M. | | 登録日 | 2018-09-01 | | 公開日 | 2019-09-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5WKP
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4MU6
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5WLW
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5WGB
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2ZL1
 | | MP1-p14 Scaffolding complex | | 分子名称: | Mitogen-activated protein kinase kinase 1-interacting protein 1, Mitogen-activated protein-binding protein-interacting protein | | 著者 | Schrag, J.D, Cygler, M, Munger, C, Magloire, A. | | 登録日 | 2008-04-02 | | 公開日 | 2008-06-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular dynamics-solvated interaction energy studies of protein-protein interactions: the MP1-p14 scaffolding complex.
J.Mol.Biol., 379, 2008
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3B8N
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3B8O
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3B8M
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3B8P
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5JG4
 | | Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila | | 分子名称: | CITRATE ANION, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Beyrakhova, K, van Straaten, K, Cygler, M. | | 登録日 | 2016-04-19 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila.
J.Biol.Chem., 291, 2016
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5KDG
 | | Crystal Structure of Salmonella Typhimurium Effector GtgE | | 分子名称: | GLYCEROL, Gifsy-2 prophage protein, SULFATE ION | | 著者 | Kozlov, G, Xu, C, Wong, K, Gehring, K, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | | 登録日 | 2016-06-08 | | 公開日 | 2016-11-16 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Crystal Structure of the Salmonella Typhimurium Effector GtgE.
PLoS ONE, 11, 2016
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